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| Date | Subscriber Growth | Mentions | Channels | |
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Channel Posts
اسئلة د.عمار
https://t.me/pharma89a/1748
اسئلة د.محمد
https://t.me/pharma89a/1750
اسئلة د.زينب
https://t.me/pharma89a/1752
ملخص محاضرات 8 - 9 - 10 د.زينب
من دفعة 88🤍
https://t.me/pharma89a/1754
عسى ان تكون ختامها مسك
all the best 🤍
| 2 |  Chloramphenicol: Broad spectrum
The main pathway of metabolism is through 3-o glucuronidation
Inactivated by chloramphenicol acetyltransferase
Use for severe infections
Has bitter taste | 329 |
| 3 |  Clindamycin: Contain chlorine group at position 7
More potent than lincomycin
Cause diarrhea
Inhibit protein synthesis
Contain sulfur
يشبه ال lincomycin بس عندة chlorine بالموقع السابع ابدال ال OH | 284 |
| 4 |  Lincomycin: Contain pyrrolidine nitrogen
Cause diarrhea
Inhibit protein synthesis
Contain sulfur | 263 |
| 5 |  Azithromycin: Contain basic tertiary amine at C9
Acid stable
Protein synthesis inhibitor
يشبه ال erythromycin بس عندة tertiary amine بالموقع 9 بدال الكيتون | 262 |
| 6 |  Clarithromycin: Is the 6-methyl ether analog of erythromycin
Have better properties than erythromycin and less GI adverse effects
Protein synthesis inhibitor
يشبه ال erythromycin بس الاختلاف بالموقع السادس عندة methyl ether بينما ال erythromycin عندة OH | 246 |
| 7 |  Erythromycin: The amino sugar at c3 is cladinose and at c5 is desosamine
Have irregular oral absorption and bitter taste
Protein synthesis inhibitor | 251 |
| 8 |  Doxycycline: Don’t have the 6-hydroxyl group
Have long half life
Have 5-alphahydroxyl group
Stable in acids and bases
يشبه ستركجر ال tetracycline بس مابيه oH بالموقع 6 | 245 |
| 9 |  Spectinomycin: Bacteriostatic
Doesn’t cause misreading mutations
حتى نفرق بالستركجرات مال ال aminoglycosides نحسب عدد الامينات
اذا 7 فحيكون streptomycin واذا 5 فيكون Amikacin واذا 6 فيكون Gentamicin واذا 2 فيكون Spectinomycin 🌚 | 250 |
| 10 | Gentamicin: Have strong activity against P.aeruginosa
Inactivated by adenylylation and acetylation | 246 |
| 11 |  Amikacin: The most resistant aminoglycoside
Can be inactivated by aminotransferase that acetylate the 6 amino and the 4-nucleotidyl transferase
Less ototoxic than kanamycin or gentamicin | 245 |
| 12 |  Streptomycin: Contain two guanidino groups and one methyl amino group
It’s problems include early resistance of bacteria strains and chronic toxicity
Can be use as adjunct to other treatments for TB | 251 |
| 13 |  New cephalosporin
Aztreonam: It’s monobactam
Have high affinity to PBP3 in gram negative bacteria only
Inactive against gram positive bacteria and anaerobes
Contain isobutyic acid oximinoacyl group | 253 |
| 14 |  New cephalsporin
Cefpirome: Fourth generation cephalosporin
Have quaternary ammonium group at 3 position
Have potency against gram positive and gram negative bacteria | 251 |
| 15 |  Ceftazidime: Third generation cephalosporin
Have antipseudomnal activity
Contain pyridinum group at position 3
Have beta lactamase resistant due to the presence of 2-methylproionicoxaminoacyl group | 249 |
| 16 |  Ceftriaxone: Third generation cephalosporin
Broad spectrum
Have long half life given once daily
Excretion in bile and urine
The unique pharmacokinetics properties due to the presence of dioxotriazine ring
Less active against B.fragilis | 270 |
| 17 |  Cefotaxime : Third generation cephalosporin
Broad spectrum | 263 |
| 18 |  Cefixime: Third generation cephalosporin
Can be given orally
Broad spectrum
Less active against S.aureus | 285 |
| 19 | ملخص محاضرات 8 - 9 - 10 د.زينب
من دفعة 88🤍 | 283 |
| 20 | Untitled document (1)_240601_215336.pdf | 369 |
