pharmacy all semester notes and study material previous year qus
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Pharmacovigilance handwritten notesβ‘οΈ
Did you know the main differences between broad-spectrum and narrow-spectrum antibiotics?
1. Range of Activity:
π- Broad-Spectrum Antibiotics: These antibiotics are effective against a wide variety of bacteria, including both Gram-positive and Gram-negative bacteria. They are often used when the specific bacteria causing an infection are not known.
β
- Narrow-Spectrum Antibiotics: These antibiotics are effective against a specific group of bacteria. They are used when the causative bacteria are identified, allowing for targeted treatment.
2. Impact on Microbiome:
π- Broad-Spectrum Antibiotics: Because they target a wide range of bacteria, they can disrupt the normal microbiome, potentially leading to side effects such as antibiotic-associated diarrhea or yeast infections.
β
- Narrow-Spectrum Antibiotics: These tend to have less impact on the normal microbiome since they target specific bacteria, which can help preserve beneficial bacteria.
3. Use Cases:
π- Broad-Spectrum Antibiotics: Often used in emergency situations or when a patient is severely ill and the specific pathogen is unknown.
β
- Narrow-Spectrum Antibiotics: Typically used when the specific bacteria have been identified through culture and sensitivity testing.
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