Leena Sudanses local and Arab board Derma Exam Questions Telegram

Recessive and dominant forms of cutis laxa can result from mutations in multiple genes, including those that encode the elastic fiber components elastin, fibulin 4, and fibulin 5. Bolongia reference

Explanation

Fibulin-5 (FBLN5)

Answer

□ Arab board dermatology part 1 2026 □Leena Sudanses local and Arab board Derma Exam Questions Telegram A mutation in which of the following proteins is most commonly associated with the autosomal dominant form of Cutis Laxa (ADCL)? A. Fibulin-5 (FBLN5) B. Fibrillin-1 C. Desmosine D. Lysyl hydroxylase

Proliferating hair matrix cells are located below the Auber line, identified as a perpendicular line drawn through the widest part of the dermal papilla. These cells have a high mitotic rate, with a rate of cell turnover similar to bone marrow Rook reference

Explanation

Below the line

Answer

□ Arab board dermatology part 1 2026 □Leena Sudanses local and Arab board Derma Exam Questions Telegram The Line of Auber is an imaginary horizontal line drawn across the widest part of the hair bulb. Where is the highest mitotic activity of the hair matrix located in relation to this line? A. At the level of the line B. Above the line C. Below the line D. In the hair shaft

Note the site of bulge area and isthmus

The inner root sheath is composed of three layers, which are the inner root sheath cuticle, Huxley layer, Henle layer. All three layer keratinize by trichohyaline granules and disintegrate when they reach the isthmus of the hair follicle. Etas part 1 book The IRS ( inner root sheath) forms a mechanically supportive tube around the hair fiber and is degraded by proteolytic enzymes at the level of the isthmus. Isthmus of follicle: Region located between the opening of the sebaceous gland and the site of insertion of the arrector pili muscle. Display trichilemmal keratinization. Bolognia reference

Explanation

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Answer

□ Arab board dermatology part 1 2026 □Leena Sudanses local and Arab board Derma Exam Questions Telegram At which level of the hair follicle does the Inner Root Sheath (IRS) disintegrate and "end"? A. Epidermis surface B. Infundibulum C. Bulge region D. Bulb

Systemic side effects of retinoid include: ■DISH syndrome-like bone changes ■Osteophyte and bony bridge formation, especially of vertebrae (rarely clinically significant at dosages for acne) ■ Anterior > posterior spinal ligament calcification ■ Extraspinal tendon and ligament calcification ■Osteoporotic changes in long bones (rare, with possible exception of long-term etretinate) ■Premature epiphyseal closure (rare) ■Periosteal thickening ■Myopathy (rare) Bolongia reference

Explanation

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Answer