Clinical Qbank(2nd year Subjects)

353 ) Ans. (c) IL 12 Ref: Jawetz 24thed Table 8-3 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

352 ) . Ans. (b) Deep Vein thrombosis Ref: Robbin’s Pathology, 9th ed. pg. 512-15; Robbins, 8th ed. pg. 517 • Buerger disease is associated with HLA B-5 and HLA-A9. • In thromboangiitis obliterans there is acute and chronic segmental inflammation of vessels with thrombosis in the lumen • Typically, the thrombus contains microabscesses with a central focus of neutrophils surrounded by inflammation 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

351 ) . Ans. (a) Controlling oxidative stress on RBC Ref: Robbin’s Pathology, 9th ed. pg. 634 • G6PD helps in neutralizing the effect of oxidative stress on the RBC. • Oxidative stress is induced by drugs like primaquine and hence in patients of G6PD there is accelerated hemolysis (intravascular during the hemolytic episode) resulting in hemoglobinuria and passage of shockingly black urine by the patient. 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

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350 ) Ans. (a) Prothrombin time Ref: Robbin’s Pathology, 9th ed. pg. 116-18 Prothrombin time ●Extrinsic pathway ●Factor 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

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349 ) Ans. (c) Tropicamide Ref: KDT, 8th ed. pg. 130 • Agents which dilate the pupillary diameter in order to facilitate fundoscopy are known as mydriatics. These are anti-muscarinic class of drugs. 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

348 ) Ans. (b) Cat scratch Necrotising noncaseating granulomas are present in cat Scratch disease caused by Bartonella Henselae. The granulomas show stellate microabscess surrounded bypalisading histiocytes. 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

347 ) Ans. (d) Lung abscess Liquefaction or colliquative necrosis also occurs commonly due to ischaemic injury and bacterial or fungal infections but hydrolytic enzymes in tissue degradation have a dominant role in causing semi-fluid material. The common examples are infarct brain and abscess cavity. 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

346) . Ans. (c) Lithium Ref: Katzung, 14th ed. pg. 527 • Lithium is DOC in manic disorder. • DOC for prophylaxis of mania: Lithium • DOC for acute attack of mania: Sedative + Atypical antipsychotics • DOC for mania in pregnancy: Atypical antipsychotics • Side effect of lithium (Mn: LITTH) ƒ L: LEUCOCYTOSIS ƒ I: Insipidus diabetes ƒ T: Tremors (MC side effect- Coarse tremor); ƒ T: Teratogenic (Ebstein anomaly) ƒ H: Hypothyroidism 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

345 ). Ans. (b) Drugs used for rare disease Ref: Katzung, 14th ed. pg. 18 • Drugs which are developed specifically for rare diseases are called orphan drugs. • These drugs are difficult to research, develop, and market due to lack of financial benefits. • Because of this a separate law known as ‘The Orphan Drug Act’ was passed in 1983. • Examples include deferipirone to treat iron overload in thalasemia patients, N-acetylcysteine to treat paracetamol poisoning etc. 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!