Longevity InTime: Autonomous AI Institute. Anti-Aging Digital Health Immortality Transhumanist AI Channel

Food and anti-parasitic treatment slow epigenetic aging in wild mice Scientists experimentally tested on wild woodland mice that feeding and anti‑parasite treatment slow the epigenetic clocks that measure aging via DNA methylation marks. A team from Edinburgh and Altos Labs built DNA‑methylation clocks for the woodland mouse and transferred them to a wild population near Edinburgh. In the September 16 version of the study, mice that were simultaneously fed and treated for intestinal parasites showed a significantly slower clock rate than untreated animals of the same chronological age. Wild animals’ ages are rarely known precisely because they are not caught at birth; body mass, tooth wear or telomere length give only rough estimates or require killing the animal. Epigenetic clocks solve this: with age, methylation changes at specific DNA sites predict age. Sarah Wolf and colleagues first trained the clocks on 74 laboratory woodland mice of known age using 177 such marks. The clocks predicted age with an error of 5.45 days on the training set and 14.64 days on independent validation. This is an order of magnitude more accurate than universal pan‑mammalian clocks trained on 18 🔗 Read original →