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9 986
There are no wise men or women in this world who can stop the death machine
It might conflict with their interests
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βοΈ Sheehan Syndrome π€±π§
A postpartum hypopituitarism caused by ischemic necrosis of the anterior pituitary following severe obstetric hemorrhage.
β Classic Association = Postpartum hemorrhage + Failure to lactate
π Pathophysiology
β’ Massive postpartum blood loss
β’ Enlarged pituitary during pregnancy is vulnerable to ischemia
β’ Anterior pituitary infarction
β’ Multiple pituitary hormone deficiencies
π Classic Features
β’ Failure to lactate (earliest sign)
β’ Secondary amenorrhea
β’ Loss of pubic/axillary hair
β’ Fatigue and cold intolerance
π Hormones Decreased
β’ β Prolactin
β’ β FSH/LH
β’ β TSH
β’ β ACTH
π Investigations
β’ Hyponatremia
β’ Low pituitary hormones
β’ MRI: Pituitary infarction or empty sella
π Management
β’ Hydrocortisone FIRST β οΈ
β’ Levothyroxine replacement
β’ Estrogen/progesterone replacement
β’ Other hormone replacement as needed
β‘ Rapid Exam Clue
Postpartum hemorrhage + inability to breastfeed = Sheehan Syndrome
π§ Memory Trick
βShe canβt feed the baby after she bled.β
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βοΈ- Types of Heart Block -β
β
π«Heart blocks occur when electrical signals from the atria to the ventricles are delayed or blockedβ
β
π«This leads to changes in the relationship between P waves and QRS complexesβ
Available now! Telegram Research 2025 β the year's key insights 
