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There are no wise men or women in this world who can stop the death machine
It might conflict with their interests
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⭐️ Sheehan Syndrome 🤱🧠
A postpartum hypopituitarism caused by ischemic necrosis of the anterior pituitary following severe obstetric hemorrhage.
⭐ Classic Association = Postpartum hemorrhage + Failure to lactate
📌 Pathophysiology
• Massive postpartum blood loss
• Enlarged pituitary during pregnancy is vulnerable to ischemia
• Anterior pituitary infarction
• Multiple pituitary hormone deficiencies
📌 Classic Features
• Failure to lactate (earliest sign)
• Secondary amenorrhea
• Loss of pubic/axillary hair
• Fatigue and cold intolerance
📌 Hormones Decreased
• ↓ Prolactin
• ↓ FSH/LH
• ↓ TSH
• ↓ ACTH
📌 Investigations
• Hyponatremia
• Low pituitary hormones
• MRI: Pituitary infarction or empty sella
📌 Management
• Hydrocortisone FIRST ⚠️
• Levothyroxine replacement
• Estrogen/progesterone replacement
• Other hormone replacement as needed
⚡ Rapid Exam Clue
Postpartum hemorrhage + inability to breastfeed = Sheehan Syndrome
🧠 Memory Trick
“She can’t feed the baby after she bled.”
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⭐️- Types of Heart Block -
🫀Heart blocks occur when electrical signals from the atria to the ventricles are delayed or blocked
🫀This leads to changes in the relationship between P waves and QRS complexes
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