PDFology

#quiz #رفح_الان 🇵🇸

تفريغ أدوية السكر د طارق المقطري #Pharmacy #Endocrine #Tafreghat #رفح_الان 🇵🇸

إيه الفرق بين Ezetimibe 🆚 Statins? 🔬 Mechanism of Action: * Ezetimibe: Acts as a cholesterol absorption inhibitor, specifically targeting Niemann-Pick C1 Like 1 (NPC1L1) protein in the small intestine. This reduces dietary cholesterol uptake. * Statins: Function as HMG-CoA reductase inhibitors, acting within the liver to decrease cholesterol synthesis. 📉 LDL-C Reduction: * Ezetimibe: Provides a modest reduction of LDL-C (low-density lipoprotein cholesterol) by 15-22%. * Statins: Offer a more potent effect, lowering LDL-C by 30-50%. ⚕️ Clinical Use: * Ezetimibe: May be used as monotherapy for mild hypercholesterolemia or in combination therapy with statins for patients requiring a more aggressive LDL-C reduction strategy. * Statins: Represent the first-line treatment for lowering LDL-C due to their efficacy. 💊 Side Effect Profile: * Ezetimibe: Generally well-tolerated with minimal adverse effects reported. * Statins: May be associated with muscle aches, fatigue, and, in rare cases, liver dysfunction. 🤔 Considerations for Selection: * Individual risk factors for cardiovascular disease. * Baseline LDL-C levels. * Patient tolerability to medications. 🔚 Conclusion: Both ezetimibe and statins play a role in managing cholesterol levels. Statins offer a more robust LDL-C reduction, making them the preferred initial therapy. Ezetimibe serves as a valuable tool for patients with statin intolerance or those requiring additional LDL-C lowering alongside a statin regimen. The optimal choice depends on individual patient characteristics and should be determined in consultation with a physician. #PDFology #Vs #رفح_الان 🇵🇸

#quiz #رفح_الان 🇵🇸

جميع المنتجات وبرندات الماركات العالمية طبق الاصل من المنتجات المختلفة (شنط و محافظ وأحذية و ملابس رجالية وأطفال ونساء و فساتين وإكسسوارات وروابط مخفية و ماركات عالمية) نجيب لكم أرخص الاسعار | مـخـتـارات مميزة من علي اكـسبـرس | يتم عرض المنتجات + المتاجر الموثوقين وأصحاب التقييمات العالية نزلتها في قناة التلغرام للتسوق بكل سهولة الرابط https://t.me/Content_to_shop طريقة الطلب المنتج بالتفاصيل مثبتة في القناة #رفح_الان 🇵🇸

كل ما تريد معرفته عن Fibromyalgia Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain and a variety of associated symptoms. Here's a concise overview for healthcare professionals: 📌 Core Characteristics: * Pain: Widespread chronic pain affecting multiple body areas, often described as deep, achy, or burning. * Tender Points: While no longer the sole diagnostic criteria, specific areas (18 in total) around the neck, shoulders, hips, knees, and chest become tender upon palpation. 🔍 Associated Symptoms: * Fatigue: A hallmark symptom, often described as profound and persistent exhaustion. * Sleep Disturbances: Difficulty falling asleep, staying asleep, or achieving restful sleep. * Cognitive Difficulties ("Fibro Fog"): Problems with memory, concentration, and focus. * Headaches: Frequent or recurring headaches of varying types. * Mood Issues: Anxiety and depression are commonly comorbid with fibromyalgia. 🔬 Diagnosis: There is no single definitive test. Diagnosis relies on a comprehensive evaluation, including: * Detailed history focusing on pain location, duration, and characteristics. * Physical examination to assess tender points and overall health. * Exclusion of other conditions that may mimic fibromyalgia. ⚙️ Management: While there's no cure, treatment aims to improve function and quality of life. This may include: * Pharmacological Therapy: Medications to manage pain, sleep disturbances, and mood issues. * Physical Therapy: To improve flexibility, strength, and reduce pain. * Stress Management Techniques: Cognitive-behavioral therapy and relaxation techniques can be helpful. * Exercise Programs: Regular exercise, tailored to individual capabilities, can significantly improve symptoms. 🌐 Reference ➡️ Clevelandclinic #PDFology #غزة 🇵🇸