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✌️✌️ *HEARTIEST CONGRATULATIONS* ✌️✌️ To *Dr Saeed Khan* For passing *MRCP UK PART 1* He has been keen member of our part 1 group. We wish him the best for his future.

*πŸ‘‰ IMPORTANT 472πŸ‘ˆ* *Few Complications Of ADPKD* ESRD Rupture of Berry`s aneurysm = SAH = Neurological deficit Recurrent urinary infections & Recurrent abdominal pain 2ry polycythemia = Hyper-Coagulable State HTN MVP (Mitral Valve Prolapse) Recurrent Kideny Stones (Uric Acid/Oxalate) Good Luck

*πŸ‘‰ IMPORTANT 471πŸ‘ˆ* *Few Complications Of Nephrotic Syndrome* Renal vein thrombosis (protein C & S deficiency)= Sudden loin pain and hematuria, AKI. Atheroma & IHD Malnutrition Recurrent Infections (Loss of Immunoglobulins in urine) DVT (Hypercoagulable state) Good Luck

*πŸ‘‰ IMPORTANT 470πŸ‘ˆ* *Few Indications for Surgery of crohn,s disease* Persistent Symptoms Despite High Dose Steroids Toxic Megacolon Strictures Intractable Fistula Perforation Or Cancer Good Luck

Dear coalleagues I regret to inform you that our tomorrow's session is cancelled due to a family gathering. We will start our sessions again after a couple of weeks. I am sorry for any inconvenience.

✌️✌️ *HEARTIEST CONGRATULATIONS* ✌️✌️ To *Dr Munmun Nipa* *Dr Suleman khan* *Dr Sana Rafique* For passing *MRCP UK PART 1* They have been keen member of our part 1 group. We wish them the best for their future.

*πŸ‘‰ IMPORTANT 469πŸ‘ˆ* *Common causes of Inherited Chronic Haemolytic Anemia* Spherocytosis (Autosomal dominant ) Thalassemia (Autosomal recessive ) Sickle cell Anemia ( Autosomal Recessive ) Good Luck

*πŸ‘‰ IMPORTANT 468πŸ‘ˆ* *Complications Of Thalassemia* Complications Of the treatment ( chelating agents ) Corneal deposits,sensory-neural hearing loss, Renal failure, arthropathy, agranulocytodsis Good Luck

*πŸ‘‰ IMPORTANT 467πŸ‘ˆ* *Complications Of Thalassemia* Complications Of the blood transfusion Infections (HBV, HCV, HIV) Secondary hemochromatosis Cardiomyopathy Diabetes mellitus (pancreas) Diabetes insipidus (pituitary)=Polyuria Liver cirrhosis Good Luck

*πŸ‘‰ IMPORTANT 466πŸ‘ˆ* *Complications Of Thalassemia* Complications Of The Disease Skeletal deformities Severe Anemia Heart failure Gall stones Good Luck

*πŸ‘‰ IMPORTANT 465πŸ‘ˆ* *Causes of Tender Hepatomegaly* Acute Viral hepatitis Budd-Chiari syndrome Congestive cardiac failure Malignancy Tricuspid regurgitation (pulsatile) Good Luck

*πŸ‘‰ IMPORTANT 464πŸ‘ˆ* *Tip for station 2 ( History taking )* When the scenario involves a patient with a known disease that presents with uncontrolled symptoms, noncompliance with currently prescribed medications can be a common differential that you have to explore in detail during the consultation. Good Luck

*πŸ‘‰ IMPORTANT 463πŸ‘ˆ* Always mention to avoid contact sports in a case of APKD. Good Luck

*πŸ‘‰ IMPORTANT 462πŸ‘ˆ* *Ultrasound diagnostic criteria in people with positive family history of ADPKD* β€’ < 30 years old: at least two unilateral or bilateral cysts (consider rescanning after 30 years old if criteria not met) β€’ 30–60 years old: two cysts in each kidney β€’ > 60 years old: more than four cysts in each kidney. Good Luck

*πŸ‘‰ IMPORTANT 461πŸ‘ˆ* *possible differentials for bilateral palpable kidneys* Bilateral hydronephrosis Amyloidosis Renal cell carcinoma Bilateral kidney cysts Tuberous sclerosis Von Hippel Lindau. Good Luck

*πŸ‘‰ IMPORTANT 460πŸ‘ˆ* *Few complications of APKD* Cysts in other organs (liver) Anaemia Abdominal pain (if a cyst bleeds or gets infected) Aneurysms in brain Mitral valve prolapse Polycythaemia Good Luck

*πŸ‘‰ IMPORTANT 459πŸ‘ˆ* *Few complications of renal transplant* 1. Infection: β€’ More prone to usual bacterial infections. β€’ Cytomegalovirus, Pneumocystis pneumonia. 2. Malignancies: β€’ Post-transplant lympho-proliferative disease. β€’ Skin-cancer-like squamous cell carcinoma. Good Luck.

*πŸ‘‰ IMPORTANT 458πŸ‘ˆ* *Tip for a case of renal transplant* For the complications of the end-stage renal failure look for β€’ Signs of anaemia β€’ Signs of hyperparathyroidism β€’ Scars from parathyroidectomy. Good Luck.

*πŸ‘‰ IMPORTANT 457πŸ‘ˆ* *Tip for a case of renal transplant* For signs of immunosuppression look for β€’ Gum hypertrophy β€’ Cushingoid signs β€’ Skin warts (papillomas) β€’ Hand tremors. Good Luck.

*πŸ‘‰ IMPORTANT 456πŸ‘ˆ* *Tip for a case of renal transplant* For the previous RRT modes look for β€’ Scars on the chest from previous sites of vascular access β€’ Unused or nonfunctioning fistulas on the arms β€’ Abdominal scars from previous peritoneal dialysis Good Luck.