pace your MRCP-PACES

✌️✌️ *HEARTIEST CONGRATULATIONS* ✌️✌️ To *Dr Saeed Khan* For passing *MRCP UK PART 1* He has been keen member of our part 1 group. We wish him the best for his future.

*👉 IMPORTANT 472👈* *Few Complications Of ADPKD* ESRD Rupture of Berry`s aneurysm = SAH = Neurological deficit Recurrent urinary infections & Recurrent abdominal pain 2ry polycythemia = Hyper-Coagulable State HTN MVP (Mitral Valve Prolapse) Recurrent Kideny Stones (Uric Acid/Oxalate) Good Luck

*👉 IMPORTANT 471👈* *Few Complications Of Nephrotic Syndrome* Renal vein thrombosis (protein C & S deficiency)= Sudden loin pain and hematuria, AKI. Atheroma & IHD Malnutrition Recurrent Infections (Loss of Immunoglobulins in urine) DVT (Hypercoagulable state) Good Luck

*👉 IMPORTANT 470👈* *Few Indications for Surgery of crohn,s disease* Persistent Symptoms Despite High Dose Steroids Toxic Megacolon Strictures Intractable Fistula Perforation Or Cancer Good Luck

Dear coalleagues I regret to inform you that our tomorrow's session is cancelled due to a family gathering. We will start our sessions again after a couple of weeks. I am sorry for any inconvenience.

✌️✌️ *HEARTIEST CONGRATULATIONS* ✌️✌️ To *Dr Munmun Nipa* *Dr Suleman khan* *Dr Sana Rafique* For passing *MRCP UK PART 1* They have been keen member of our part 1 group. We wish them the best for their future.

*👉 IMPORTANT 469👈* *Common causes of Inherited Chronic Haemolytic Anemia* Spherocytosis (Autosomal dominant ) Thalassemia (Autosomal recessive ) Sickle cell Anemia ( Autosomal Recessive ) Good Luck

*👉 IMPORTANT 468👈* *Complications Of Thalassemia* Complications Of the treatment ( chelating agents ) Corneal deposits,sensory-neural hearing loss, Renal failure, arthropathy, agranulocytodsis Good Luck

*👉 IMPORTANT 467👈* *Complications Of Thalassemia* Complications Of the blood transfusion Infections (HBV, HCV, HIV) Secondary hemochromatosis Cardiomyopathy Diabetes mellitus (pancreas) Diabetes insipidus (pituitary)=Polyuria Liver cirrhosis Good Luck

*👉 IMPORTANT 466👈* *Complications Of Thalassemia* Complications Of The Disease Skeletal deformities Severe Anemia Heart failure Gall stones Good Luck

*👉 IMPORTANT 465👈* *Causes of Tender Hepatomegaly* Acute Viral hepatitis Budd-Chiari syndrome Congestive cardiac failure Malignancy Tricuspid regurgitation (pulsatile) Good Luck

*👉 IMPORTANT 464👈* *Tip for station 2 ( History taking )* When the scenario involves a patient with a known disease that presents with uncontrolled symptoms, noncompliance with currently prescribed medications can be a common differential that you have to explore in detail during the consultation. Good Luck

*👉 IMPORTANT 463👈* Always mention to avoid contact sports in a case of APKD. Good Luck

*👉 IMPORTANT 462👈* *Ultrasound diagnostic criteria in people with positive family history of ADPKD* • < 30 years old: at least two unilateral or bilateral cysts (consider rescanning after 30 years old if criteria not met) • 30–60 years old: two cysts in each kidney • > 60 years old: more than four cysts in each kidney. Good Luck

*👉 IMPORTANT 461👈* *possible differentials for bilateral palpable kidneys* Bilateral hydronephrosis Amyloidosis Renal cell carcinoma Bilateral kidney cysts Tuberous sclerosis Von Hippel Lindau. Good Luck

*👉 IMPORTANT 460👈* *Few complications of APKD* Cysts in other organs (liver) Anaemia Abdominal pain (if a cyst bleeds or gets infected) Aneurysms in brain Mitral valve prolapse Polycythaemia Good Luck

*👉 IMPORTANT 459👈* *Few complications of renal transplant* 1. Infection: • More prone to usual bacterial infections. • Cytomegalovirus, Pneumocystis pneumonia. 2. Malignancies: • Post-transplant lympho-proliferative disease. • Skin-cancer-like squamous cell carcinoma. Good Luck.

*👉 IMPORTANT 458👈* *Tip for a case of renal transplant* For the complications of the end-stage renal failure look for • Signs of anaemia • Signs of hyperparathyroidism • Scars from parathyroidectomy. Good Luck.

*👉 IMPORTANT 457👈* *Tip for a case of renal transplant* For signs of immunosuppression look for • Gum hypertrophy • Cushingoid signs • Skin warts (papillomas) • Hand tremors. Good Luck.

*👉 IMPORTANT 456👈* *Tip for a case of renal transplant* For the previous RRT modes look for • Scars on the chest from previous sites of vascular access • Unused or nonfunctioning fistulas on the arms • Abdominal scars from previous peritoneal dialysis Good Luck.