pace your MRCP-PACES

👉 *IMPORTANT 150* 👈 *Symptoms indicating increase probability of asthma* Wheeze, SOB, chest tightness Diurnal variation Response to exercise, allergen, cold air Symptoms after aspirin or ß-blocker History of atopy Family history atopy/asthma Widespread wheeze heard on auscultation Unexplained low FEV₁ or PEF Unexplained peripheral blood eosinophilia Good luck.

👉 *IMPORTANT 149* 👈 *Common causes of Bronchiectasis* : ( very common ) *Congenital* : Cystic fibrosis Young’s syndrome Primary ciliary dyskinesia Kartagener’s syndrome *Post-infection* : Measles Pertussis Bronchiolitis pneumonia TB HIV *Other* : Bronchial obstruction (tumour, foreign body); Allergic bronchopulmonary aspergillosis hypogammaglobulinaemia Rheumatoid arthritis Ulcerative colitis Idiopathic Good luck.

👉 *IMPORTANT 148* 👈 *Some drugs causing acute pericarditis* procainamide hydralazine penicillin isoniazid Good luck.

👉 *IMPORTANT 147* 👈 *Certain drugs causing myocarditis* Cyclophosphamide trastuzumab penicillin chloramphenicol sulfonamides methyldopa spironolactone phenytoin carbamazepine Good luck.

👉 *IMPORTANT 146* 👈 *Modified Duke criteria for infective endocarditis* *Major criteria* : Positive blood culture: • Typical organism in 2 separate cultures or • Persistently +ve blood cultures, eg 3 >12h apart (or majority if >3) or • Single positive blood culture for Coxiella burnetii. • Endocardium involved: . Positive echocardiogram (vegetation, abscess, pseudoaneurysm, dehiscence of prosthetic valve) or • Abnormal activity around prosthetic valve on PET/CT or SPECT/CT or • Paravalvular lesions on cardiac CT. *Minor criteria* : • Predisposition (cardiac lesion; IV drug abuse). • Fever >38°C • Vascular phenomena (emboli, Janeway's lesions, etc.). • Immunological phenomena (glomerulonephritis, Osler's nodes, etc.). • Positive blood culture that does not meet major criteria. *How to diagnose* : Definite infective endocarditis: 2 major or 1 major and 3 minor or all 5 minor criteria. Good luck.

👉 *IMPORTANT 145* 👈 Please remember Fever + new murmur = endocarditis until proven otherwise Good luck.

👉 *IMPORTANT 144* 👈 *Heart and Thyrotoxicosis* You may find in Thyrotoxicosis: Tachycadia AF ± emboli Wide pulse pressure Hyperdynamic apex Loud heart sounds Ejection systolic murmur Pleuro pericardial rub Angina high-output cardiac failure Good luck.

👉 *IMPORTANT 143* 👈 *Heart and Systemic Sclerosis* You may find in Systemic Sclerosis: Pericarditis Pericardial effusion Myocardial fibrosis Myocardial ischaemia Conduction defects Ccardiomyopathy Good luck.

👉 *IMPORTANT 142* 👈 *Heart and Systemic Lupus Erythematosus* You may find in Systemic Lupus Erythematosus: Pericarditis/effusion Myocarditis Libman–Sacks endocarditis Mitral valve prolapse Coronary arteritis Good luck.

👉 *IMPORTANT 141* 👈 *Heart and Sarcoidosis* You may find in Sarcoidosis: Complete AV due Infiltrating granulomas Ventricular or supraventricular tachycardia Myocarditis CCF restrictive cardiomyopathy. ECG may show Q waves Good luck.

👉 *IMPORTANT 140* 👈 *Heart and Rheumatoid Arthritis* You may find in Rheumatoid Arthritis: Conduction defects Pericarditis LV dysfunction Aortic regurgitation Good luck.

Dear all I regret to inform you that our session for tomorrow is cancelled due to some family commitments and travelling. Our next session will be on 27 Nov 22 if all goes well. I am sorry for any inconvenience. Good luck

👉 *IMPORTANT 139* 👈 *Heart and Polyarteritis nodosa* You may find in Polyarteritis nodosa : Small and medium vessel vasculitis Angina Myocardial Infarction Arrhythmias Congestive cardiac Failure Pericarditis Conduction defects. Good luck.

👉 *IMPORTANT 138* 👈 *Heart and Noonan syndrome ( common in some centers )* You may find in Noonan syndrome: Atrial Septal Defect Pulmonary stenosis Good luck.

👉 *IMPORTANT 137* 👈 *Heart and Myotonic dystrophy* You may find in Myotonic dystrophy: Progressive conduction defects arrhythmias LV dysfunction Good luck.

👉 *IMPORTANT 136* 👈 *Heart and Marfan’s syndrome* You may find in Marfan’s syndrome : Mitral valve prolapse Aortic Regurgitation Aortic dissection Good luck.

👉 *IMPORTANT 135* 👈 *Heart and Hypothyroidism* You may find in Hypothyroidism: Sinus bradycardia Low pulse pressure Pericardial effusion High blood pressure Coronary artery disease Low-voltage ECG. Good luck.

👉 *IMPORTANT 134* 👈 *Heart and Haemochromatosis* You may find in Haemochromatosis: AF Cardiomyopathy Good luck.

👉 *IMPORTANT 133* 👈 *Heart and Friedreich’s ataxia* You may find in Friedreich’s ataxia: Hypertrophic cardiomyopathy Good luck.

👉 *IMPORTANT 132* 👈 *Heart and Ehlers–Danlos syndrome* You may find in Ehlers–Danlos syndrome: Mitral valve prolapse Aortic aneurysm and dissection: Good luck.