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🟢 ONLINE COURSE NO. 67 – ADMISSIONS OPEN!
📅 23 Feb – 13 March 2026
🎯 PACES MRCP (UK) & CLINICAL EXAM MRCPI
🚨 At a very affordable fee
✅ 15-Day Intensive Online Course
✅ Covers ALL 7 SKILLS in detail (as in our weekly free sessions)
✅ Practice & discussion of 90+ exam cases (including recent diets), covering:
• 45 cases of consultations
• 45 cases of communications.
✅ Personalized feedback to sharpen weak areas
✅ Ideal for beginners & upcoming exam candidates
🎓 Slots Available:
🔹 Active participation – First come, first served
🔹 Listener slots also available
📩 Join Us!
📱 WhatsApp: +92 334 6036496
📧 Email: drtanzeelbukhari@gmail.com
🚀 Join, Learn, Practice & Succeed!
GOOD LUCK
2 522
🟢 ONLINE COURSE NO. 67 – ADMISSIONS OPEN!
📅 23 Feb – 13 March 2026
🎯 PACES MRCP (UK) & CLINICAL EXAM MRCPI
🚨 At a very affordable fee
✅ 15-Day Intensive Online Course
✅ Covers ALL 7 SKILLS in detail (as in our weekly free sessions)
✅ Practice & discussion of 90+ exam cases (including recent diets), covering:
• 45 cases of consultations
• 45 cases of communications.
✅ Personalized feedback to sharpen weak areas
✅ Ideal for beginners & upcoming exam candidates
🎓 Slots Available:
🔹 Active participation – First come, first served
🔹 Listener slots also available
📩 Join Us!
📱 WhatsApp: +92 334 6036496
📧 Email: drtanzeelbukhari@gmail.com
🚀 Join, Learn, Practice & Succeed!
GOOD LUCK
2 522
*🩺 Management Essential 13 – Community-Acquired Pneumonia (CAP)*
*Initial assessment*
• ABCDE, sepsis screening
• Assess severity (clinical judgement over rigid scores)
*Immediate management*
• Oxygen if hypoxic
• IV or oral antibiotics based on severity and local policy
• Blood cultures before antibiotics if severe, but do not delay treatment
*Supportive care*
• IV fluids if hypotensive or dehydrated
• Analgesia and antipyretics
• Early mobilisation when stable
*Key safety pearls*
• Elderly may present atypically (confusion, falls)
• Reassess at 24–48 hours for response
• Failure to improve → think complications or alternative diagnosis
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🩺 Management Essential 12 – Acute COPD Exacerbation
Initial priorities
• Controlled oxygen: target SpO₂ 88–92%
• Assess for infective trigger, pneumothorax, or PE
Immediate treatment
• Nebulised salbutamol ± ipratropium
• Oral prednisolone (or IV hydrocortisone if severe)
• Antibiotics if purulent sputum or clinical infection
Ventilatory support
• NIV (BiPAP) if:
o pH <7.35 with raised PaCO₂
o Persistent respiratory distress despite treatment
• Escalate early; avoid delay
Key safety pearls
• Excess oxygen worsens hypercapnia
• Reversible cause → treat aggressively
• Discuss ceiling of care early in advanced disease
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*🩺 Management Essential 11 – Acute Severe Asthma*
*(by pace your MRCP – Dr Tanzeel Bukhari)*
*Initial priorities*
• ABCDE approach; treat first, do not delay for investigations
• Sit patient upright, continuous monitoring (SpO₂, HR, RR)
*Immediate treatment*
• High-flow oxygen to maintain SpO₂ 94–98%
• Back-to-back nebulised salbutamol (oxygen-driven)
• Add ipratropium bromide in severe/life-threatening attacks
• IV hydrocortisone (or oral prednisolone if able)
*Escalation*
• IV magnesium sulfate if poor response to nebulisers
• Consider IV salbutamol or aminophylline in ICU setting
• Early senior/ICU involvement if:
o Silent chest, exhaustion, rising PaCO₂, or reduced GCS
*Key safety pearls*
• Normal or rising PaCO₂ = impending respiratory failure
• Avoid sedatives
• Early intubation only by experienced team
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🩺 Symptom Snapshot 15 – Chronic Headache
(by pace your MRCP – Dr Tanzeel Bukhari)
1️⃣ Tension-Type Headache
Chronic, bilateral, pressing or tight pain
No nausea or focal neurological symptoms
Often related to stress, anxiety, or poor posture
2️⃣ Medication Overuse Headache
Daily or near-daily headache
History of frequent analgesic or triptan use
Improves only after withdrawal of overused drugs
3️⃣ Raised Intracranial Pressure (ICP)
Morning headache, worse on coughing or straining
May be associated with vomiting or visual disturbance
Requires urgent neuroimaging
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🩺 Symptom Snapshot 14 – Sudden Severe Headache
(by pace your MRCP – Dr Tanzeel Bukhari)
1️⃣ Subarachnoid Haemorrhage (SAH)
Sudden “thunderclap” headache, maximal at onset
May be associated with neck stiffness, vomiting, collapse
Medical emergency → urgent CT head ± lumbar puncture
2️⃣ Intracerebral Haemorrhage
Acute severe headache with focal neurological deficit
Often associated with uncontrolled hypertension
Reduced level of consciousness may be present
3️⃣ Cerebral Venous Thrombosis (CVT)
Severe headache ± seizures or focal deficits
Risk factors: pregnancy, OCP use, thrombophilia
Requires MR venography for diagnosis
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🩺 Symptom Snapshot 13 – Headache
(by pace your MRCP – Dr Tanzeel Bukhari)
1️⃣ Tension-Type Headache
Bilateral, tight or band-like pain
No nausea or neurological deficit
Often related to stress or poor posture
2️⃣ Migraine
Unilateral, throbbing headache
Associated with nausea, photophobia, phonophobia
May be preceded by aura
3️⃣ Secondary Headache (Red Flags)
New or worsening headache, especially >50 years
Associated with fever, focal neurology, or raised BP
Consider causes like intracranial bleed, meningitis, or GCA
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Investigation Pearl 14 – Hyperkalaemia: ECG > Number
(by pace your MRCP – Dr Tanzeel Bukhari)
Key Principle: ECG changes define urgency more than serum K⁺.
Progression: peaked T → PR prolongation/P loss → QRS widening → sine wave → arrest.
Exam tip: Treat immediately if ECG changes are present.
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Investigation Pearl 13 – Normocytic Anaemia Can Be Serious
(by pace your MRCP – Dr Tanzeel Bukhari)
Key Principle: Normal MCV does not exclude significant pathology.
Consider acute blood loss, anaemia of chronic disease, CKD, haemolysis, mixed deficiencies.
Exam tip: Use reticulocytes, ferritin/iron, CRP and renal profile.
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Investigation Pearl 12 – Hyponatraemia: Volume Status First
(by pace your MRCP – Dr Tanzeel Bukhari)
Key Principle: Management depends on volume status (hypo/eu/hypervolaemic).
Treating sodium without assessing volume can worsen the condition (e.g., fluids in SIADH).
Exam tip: Clinical assessment comes first.
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Dear colleagues due to sour throat we have to cancel our tomorrow's session, as i need to get some voice rest.I regret any inconvenience,
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*🩺 Symptom Snapshot 10 – Wheeze*
*(by pace your MRCP – Dr Tanzeel Bukhari)*
*1️⃣ Asthma*
Episodic wheeze with chest tightness and breathlessness
Often worse at night or early morning
Triggers include allergens, exercise, cold air
*2️⃣ COPD*
Persistent wheeze with chronic cough and sputum
Usually in smokers or ex-smokers
Progressive and less reversible than asthma
*3️⃣ Cardiac Asthma (Left Ventricular Failure)*
Wheeze due to pulmonary oedema
Associated with orthopnoea and PND
Improves with diuretics, not bronchodilators
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*🩺 Symptom Snapshot 11 – Stridor*
*(by pace your MRCP – Dr Tanzeel Bukhari)*
*1️⃣ Upper Airway Obstruction (Tumour / Foreign Body)*
High-pitched inspiratory noise
Often associated with voice change or dysphagia
Red flag → urgent ENT assessment
*2️⃣ Anaphylaxis / Laryngeal Oedema*
Acute onset stridor with facial or lip swelling
May have hypotension, urticaria
Medical emergency → adrenaline immediately
*3️⃣ Post-intubation or Tracheal Stenosis*
Progressive exertional stridor
History of prolonged intubation or tracheostomy
Fixed upper airway narrowing
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*🩺 Symptom Snapshot 12 – Exercise Intolerance*
*(by pace your MRCP – Dr Tanzeel Bukhari)*
*1️⃣ Heart Failure*
Reduced ability to perform physical activity
Associated with breathlessness, fatigue, ankle swelling
Progressive decline over time
*2️⃣ Chronic Lung Disease (COPD / ILD)*
Early fatigue and breathlessness on exertion
May have chronic cough or crackles
Oxygen desaturation on exertion
*3️⃣ Anaemia*
Generalised fatigue and reduced exercise capacity
May have pallor, tachycardia
Confirmed on full blood count
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Investigation Pearl 8 – ABG Red Flag: Normal PaCO₂ in Acute Breathlessness
Key Principle: Acute breathlessness usually causes hyperventilation → low PaCO₂.
Normal PaCO₂ suggests fatigue and impending ventilatory failure; raised PaCO₂ suggests established failure.
Exam tip: Low CO₂ = compensation; normal CO₂ = danger; high CO₂ = failure.
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