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RN_STUDY_BUDDY

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https://www.instagram.com/rn_study_buddy?utm_source=ig_web_button_share_sheet&igsh=ODdmZWVhMTFiMw== Lucifer Morningstar: You have no one to blame but yourself for who you are. 🔥 Responsibility makes u bitter or better 😉 https://t.me/+RCFKLPOsV4BiOGM9

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📌 Hypercalcemia – Causes Made Easy (CHIMPANZEES) 🦍 Mnemonic: CHIMPANZEES C – Calcium supplementation H – Hyperparathyroidis
📌 Hypercalcemia – Causes Made Easy (CHIMPANZEES) 🦍 Mnemonic: CHIMPANZEES C – Calcium supplementation H – Hyperparathyroidism (most common outpatient cause) I – Iatrogenic causes; Immobilization M – Multiple myeloma; Milk-alkali syndrome P – Parathyroid hyperplasia A – Alcohol-related causes N – Neoplasms (most common inpatient cause) Z – Zollinger-Ellison syndrome E – Excess Vitamin D E – Excess Vitamin A S – Sarcoidosis 💡 Quick Clinical Pearls 🔹 Hyperparathyroidism and malignancy account for most cases of hypercalcemia. 🔹 Classic symptoms: "Stones, Bones, Groans, Thrones & Psychiatric Overtones" 🪨 Kidney stones 🦴 Bone pain 🤢 Abdominal pain, constipation 🚽 Polyuria (frequent urination) 🧠 Confusion, depression, lethargy 🔹 ECG finding: Shortened QT interval ❤️ 🔹 Emergency treatment: IV normal saline 💧 Calcitonin 🩺 Bisphosphonates (e.g., Zoledronic acid) 💉 📚 Exam Tip: When a question mentions high calcium + bone pain + anemia + renal failure, think Multiple Myeloma first.
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❇️ Common Headache Types ▶️ Stress Headache (Tension-type) → Pain forms a tight band around the forehead and back of the head → Dull, aching sensation → Often triggered by stress, poor posture, or fatigue ▶️ Migraine → Intense, throbbing pain on one side of the head → Often associated with nausea, sensitivity to light/sound → Can have visual auras before the headache starts ▶️ Hypertension Headache → Pain usually at the back of the head or neck → Often pulsating and occurs during high blood pressure spikes → May worsen with physical activity ▶️ Cluster Headache → Severe pain around one eye → Occurs in clusters (repeated over weeks/months) → May cause tearing, nasal congestion on the same side ▶️ Sinus Headache → Pain and pressure around the forehead, cheeks, and nose → Often worsens with movement or bending down → Usually accompanied by sinus infection symptoms (e.g., nasal congestion) ▶️ Post-Traumatic Headache → Develops after a head injury → Pain can be localized or widespread → May be accompanied by dizziness or memory issues ▶️ TMJ Headache → Pain near the temples or jaw joint → Associated with jaw clenching, grinding, or TMJ disorder → Can radiate to ear or neck ▶️ Exertion Headache → Triggered by physical activity (exercise, coughing, sex) → Throbbing pain often at the front or sides of the head → Usually short-lasting but intense ▶️ Thunderclap Headache → Sudden, severe headache that reaches peak intensity within seconds → Medical emergency—can indicate bleeding in the brain or aneurysm → Requires immediate medical attention
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🧠 Parkinson’s vs Huntington’s — Know the Difference ⸻ 1️⃣ Parkinson’s Disease 🔸 Mnemonic: TRAP • Tremor → resting (“pill-rolling”) • Rigidity → cogwheel • Akinesia / Bradykinesia • Postural instability 🔸 Other features: • Masked (expressionless) face • Shuffling gait with reduced arm swing • Micrographia, hypophonia 🧩 Pathology: Degeneration of Substantia Nigra → ↓ Dopamine 🧬 Genetics: Usually sporadic. Rare familial forms → SNCA, PARK2 ⸻ 2️⃣ Huntington’s Disease 🔸 The triad: CHOREA + COGNITION + PSYCHIATRIC • Chorea → involuntary jerky, dance-like movements • Dementia → personality changes, cognitive decline • Psychiatric → depression, psychosis, impulsivity 🔸 Onset: Typically 30–50 years old • Younger onset = more severe (anticipation!) 🧩 Pathology: Degeneration of Caudate Nucleus → loss of GABA neurons 🧬 Genetics: Autosomal Dominant — CAG trinucleotide repeat expansion on chromosome 4 ⸻ 3️⃣ Head-to-Head Comparison ➊ Movement type • Parkinson’s → TOO LITTLE movement (hypokinesia) • Huntington’s → TOO MUCH movement (hyperkinesia) ➋ Pathology • Parkinson’s → Substantia Nigra (↓ Dopamine) • Huntington’s → Caudate Nucleus (↓ GABA) ➌ Genetics • Parkinson’s → mostly sporadic • Huntington’s → always autosomal dominant, 100% penetrance ➍ Treatment • Parkinson’s → Levodopa/Carbidopa (replace dopamine) • Huntington’s → Tetrabenazine for chorea (no disease-modifying therapy) ⸻ ⚠️ Exam Pearl 🔹 Huntington’s shows ANTICIPATION — each generation presents earlier and more severely 🔹 If you see choreiform movements + psychiatric symptoms in a young adult → think Huntington’s first ⸻ 📚 Master movement disorders and all of neurology in our high-yield neurology book: 🔗 www.mediconotes.com ⸻ #Parkinsons #Huntingtons #Neurology #MovementDisorders #MedicalEducation
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