Pharmacology
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👍 24❤ 12👎 2🔥 2
Correct Answer - D
Ans. is 'd' i.e., Shows cross reactivity with other penicillins
Aztreonam
It belongs to monobactams group of 13-lactam antibiotics.
It is active against gram negative organisms including
pseudomonas, but has no activity against gram positive organisms
or anaerobes fi-lactam antibiotic with aminoglycosides spectrum.
It is the only fi-lactam antibiotic that lack cross-reactivity with other
P-lactam antibiotics, permiting its used in patients allergic to
penicillins or cephalosporins.
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Pharmacology
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👍 11❤ 5
Not true about aztreonam ?#PYQ#FMGE#NEETPG#INICETAnonymous voting
- A.beta lactam
- B.Monobactam
- C.Active Against pseudomonas
- D.Can cross reactive with other penicillin
🏆 11👍 8❤ 7🔥 2🥰 1👏 1
Correct Answer - B
Answer: B - Neuro-endopeptidase inhibitor
Sacubitril,a prodrug inhibiting neuro-endopeptidase enzyme
Activated to Sacubitril,
Inhibiting enzyme neprilysin (Neutral endopeptidases)
Combination drug used in heart failure patients Usually combined with ACE inhibitors like valsartan in ratio of 1:1
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Pharmacology
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❤ 9👍 7👎 2
Sacubitril is,
#PYQ#FMGE#NEETPG#INICETAnonymous voting
- A.ACE inhibitior
- B.Neuro endopeptidase inhibitor
- C.Beta blocker
- D.RAAS inhibitior
👍 41👏 4❤ 3🔥 1
Correct Answer - C
Ans. C. Primaquine
Gametocidal - Acts on gametocytes
For all species: Primaquine, artimisinins
For P. vivax: Chloroquine, quinine
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Pharmacology
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👍 13❤ 1
Gametocidal antimalarial drug for all
species of plasmodium ?#PYQ#FMGE#NEETPG#INICETAnonymous voting
- A.Quinine
- B.Mefloquine
- C.Primaquine
- D.Chloroquine
👍 32❤ 10👏 3🔥 1
Correct Answer - B
Ans. B. Area Under Curve decreased by 35%
[Ref Kucers: the use of antibiotics 6th edn by M Lindsay Grayson
p.1598]
Co administration of ritonavir with rifampicin:
Recommendation is to use the combination with caution.
Area under curve decreased by 35%
There is no change in rifampicin concentration
It is recommended to monitor the antiretroviral activity of ritonavir
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👍 25👎 1
What is the effect of co administration of
rifampicin and ritonavir in patients
suffering from AIDS? #PYQ#FMGE#NEETPG#INICETAnonymous voting
- A.Area Under Curve decreased by 15%
- B.Area Under Curve decreased by 35%
- C.Area Under Curve increased by 35%
- D.Area Under Curve increased by 35%
👍 23❤ 5
Correct Answer - C
Ans. is 'c' i.e., Finasteride
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Pharmacology
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👍 7
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