Pathology - Malek

Cirhhosis as a late manifestation? a 1-antitrypsin defeciency Early > panacinar emphysema Later> cirhhosis

33. Chronic hoarsness. Mass removed from larynx. Histopathological examination shows dilated blood vessels with hyalinization of the stroma. Laryngeal nodule

Celiac disease microscopical finding villous atrophy, crypt hyperplasia, and intraepithelial lymphocytosis

31. Complication of ABO incompatibility represent ? 10%

Child with hemarthrosis and joint mobility issues, with <1% FVIII and bleeding tendency. Presnets with emergency attack of bleeding, what is the first line management? A. recombinant FVIII infusion B. vasopressin (DDAVP) A

A 25-year-old man has a 5-year history of celiac sprue. Four days after a mild upper respiratory infection, he begins passing dark red-brown urine. The dark urine persists for the next 3 days and then becomes clear and yellow, only to become red-brown again month later. There are no remarkable findings on physical examination. Urinalysis shows a pH of 6.5; specific gravity, 1.018; 3+ hematuria; 1+ proteinuria; and no glucose or ketones. Microscopic examination of the urine shows RBCs, but no WBCs, casts, or crystals. A 24- hour urine protein level is 200 mg. A renal biopsy specimen from the glomeruli of this patient is most likely to show which of the following alterations? A. Diffuse cellular proliferation and basement membrane thickening B. Granular staining of the basement membrane by anti-IgG antibodies C. Mesangial IgA staining by immunofluorescence D. Subepithelial electron-dense deposits E. Thrombosis within the glomerular capillaries C

A 33-year-old female has had a cervical lymphadenopathy. Biopsy of one lymph node reveal thick bands of fibrous connective tissue with intervening lymphocytes, plasma cells, eosinophils. macrophages, and occasional Reed-Sternberg cells. The subtype her Hodgkin disease is? A. Lymphocyte predominant B. Mixed cellularity C. Lymphocyte depleted D. Nodular lymphocyte predominant E. Nodular sclerosis E

The most common type of cervical cancer is? Nonkeratinizing squamous cell carcinoma

A 38-year-old presented with a painless testicular mass, the mass was excised and stained for histopathology. The microscopical appearance confirms the diagnosis of a seminoma. Regarding this condition, which is true? A. It is the most common tumor in children aged 1-5yo B. The tumor frequently contains foci of coagulation necrosis with hemorrhage C. It is usually confined to the testis D. 95% of tumors stain positive for human chorionic gonadotropin (hCG) E. A neutrophilic infiltrate is usually present

49-year-old woman taking aspirin for increasing joint pain in her hands presents with increasing pain in her mid sternal area. Gastroscopy reveals multiple, scattered, punctate hemorrhagie areas in her gastric mucosa. Biopsies were taken reveal mucosal erosions with edema and hemorrhage. No mucosal ulceration is seen. Which of the following is the most likely diagnosis? A. Active chronic gastritis B. Acute gastritis C. Autoimmune gastritis D. Chronic gastritis

Bleeding from the nipple in a 45-year-old woman, without a palpable breast mass should suggest: intraductal papilioma

Massive splenomegaly is a characteristic clinical feature of all of the following diseases EXCEPT: A. Chronic myelogenous leukemia (CML) B. Myelofibrosis with myeloid metaplásia C. Gaucher disease D. Kala-azar. E. Infectious mononucleosis

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For more than a decade, a 45-year-old male has had poorly controlled hypertension in the range of 160/95 mm Hg. For the past 3 months, his blood pressure has increased to 250/125 mm Hg. He now has a serum creatinine level of 3.8 mg/dL. Which of the following vascular lesions is most likely to be found in the kidneys? A. Hyperplastic arteriolosclerosis B. Granulomatous arteritis C. Fibromuscular dysplasia D. Polyarteritis nodosa A

Which of the features of a spinal tap (cerebrospinal fluid examination) indicate viral infection? Predominance of lymphocyte باقي الخيارات بعيدات بسهولة تحلوه اذا تكرر

What makes cholesterol gallstones more likely to be formed? A. Biliary infection B. Chronic hemolysis C. Hypermobility of gallbladder D. Supersaturation of bile with cholesterol E. Biliary infection and gallbladder hypermobility D