Pathology - Malek

Regarding time limits for giving blood transfusion products: A. whole blood must be administered within 30mins of removing from refrigirator B. platelet concentrate as soon as possible C. Cyroprecipitate immediately D. interval between plateletpheresis donations should not exceed more than twice a week

Terminal molecule of blood group A chain A. N-acetyl galactosamine B. N-acetyl glucosamine C. L-fucos D. galactose

In blood donation, which is false? A. Patient with a history of hepatitis A infection is permanently deferred B. Patient with brucellosis is permenantly deferred C. Patient who had a tattoo is deferred for a year

72. Cytochemical stain positive for lymphocytes A. PAS B. Sudan black C. Myeloperoxidas D. Alkaline phosphatase A

Basophilia is a feature of? A. Acute lymphocytic leukemia B. Chronic myeloblastic leukemia C. Multiple myeloma C

A 70 year old man has a low-grade urothelial bladder cancer that invades the muscle layer. What is the most important prognostic factor? Muscle invasion

69. A 62-year-old man is taken to the emergency department in a state of inebriation. He is well known there because this scenario has been repeated many times over 15 years. On physical examination, he is afebrile. The spleen tip is palpable, and the liver edge is firm. Laboratory studies show hemoglobin of 8.2 g/dL, hematocrit of 25.1%, MCV of 107 µm3, platelet count of 135,000/mm3, and WBC count of 3920/mm3. The peripheral blood smear shows prominent anisocytosis and macrocytosis. Polychromatophilic RBCs are difficult to find. A few of the neutrophils show six to seven nuclear lobes. Which of the following is the most likely explanation of these findings in his peripheral blood cells? A. Diminished nuclear maturation from impaired DNA synthesis B. Extravascular hemolysis of antibody-coated cells C. Imbalance in synthesis of a-globin and B-globin chains D. Increased susceptibility to lysis by complement E. Reduced deformability of RBC membranes A

A 23-year-old African-American man passes dark reddish brown urine 3 days after taking an anti-inflammatory medication that includes phenacetin. He is surprised, because he has been healthy all his life and has had no major illnesses. On physical examination, he is afebrile, and there are no remarkable findings. CBC shows a mild normocytic anemia, but the peripheral blood smear shows precipitates of denatured globin (Heinz bodies) with supravital staining and scattered "bite cells" in the population of RBCs. Which of the following is the most likely diagnosis? A. a-Thalassemia minor B. B-Thalassemia minor C. Glucose-6-phosphate dehydrogenase deficiency D. Sickle cell trait E. Abnormal ankyrin in RBC cytoskeletal membrane C

Most common type of thyroid carcinoma? Papillary

After having an attack of MI, a 60-year old man decides to specific diet to improve his condition. A decraese in which of the following serum markers suggests that his diet was successful? A. Glucose B. Albumin C. Cholesterol D. Creatinine C

64. A biopsy taken from the liver of an alcoholic patient shows fatty changes. If this patient decides to abstain from drinking alcohol, which of the following is excpected to happen? A. Nothing will change. B. The liver will progress to fatty hepatitis. C. The liver will return back to normal. C

B

61. A 35-year-old man has had an outbreak of pruritic lesions over the extensor surfaces of the elbows and knees during the past month. He has a history of malabsorption that requires him to eat a special diet, but he has had no previous skin problems. On physical examination, the lesions are 0.4- to 0.7-cm vesicles. A 3-mm punch biopsy of one of the lesions over the elbow is performed and on microscopic examination shows accumulation of neutrophils at the tips of dermal papillae and formation of small blisters caused by separation at the dermoepidermal junction. Immunofluorescence studies show granular deposits of IgA localized to tips of dermal papillae. Laboratory studies show serum antigliadin antibodies. What is the most likely diagnosis? A. Bullous pemphigoid B. Contact dermatitis C. Dermatitis herpetiformis D. Discoid lupus erythematosus E. Erythema multiforme C

A 34-year-old woman has noticed a bloody discharge from the nipple of her left breast for the past 3 days. On physical examination, the skin of the breasts appears normal, and no masses are palpable. There is no axillary lymphadenopathy. She has regular menstrual cycles and is using oral contraceptives. Excisional biopsy is most likely to show which of the following lesions in her left breast? A. Acute mastitis B. Fibroadenoma C. Intraductal papilloma D. Phyllodes tumor E. Sclerosing adenosis C

A 35-year-old woman has had increasing abdominal enlargement for the past 6 months. She states that she feels like she is pregnant, but results of a pregnancy test are negative. On physical examination, there is abdominal distention with a fluid wave. A pelvic ultrasound scan shows bilateral cystic ovarian masses, 10 cm on the right and 7 cm on the left. The masses are surgically removed. On gross examination, the excised masses are unilocular cysts filled with clear fluid, and papillary projections extend into the central lumen of the cyst. Microscopic examination shows that the papillae are covered with atypical cuboidal cells that invade underlying stroma. Psammoma bodies are present. What is the most likely diagnosis? A. Endometrioid tumor B. Cystadenocarcinoma C. Dysgerminoma D. Granulosa cell tumor E. Mature cystic teratoma B

58. A 22-year-old woman experiences sudden onset of severe lower abdominal pain. Physical examination shows no masses, but there is severe tenderness in the right lower quadrant. A pelvic examination shows no lesions of the cervix or vagina. Bowel sounds are detected. An abdominal ultrasound scan shows a 4-cm focal enlargement of the proximal right fallopian tube. A dilation and curettage procedure shows only decidua from the endometrial cavity. Which of the following laboratory findings is most likely to be reported for this patient? A. Cervical culture positive for Neisseria gonorrhoeae B. Detection of human chorionic gonadotropin in serum C. 69, XXY karyotype on decidual tissue cells D. Pap smear showing pseudohyphae of Candida E. Positive result of serologic testing for syphilis

A 52-year-old woman has noted increasing size of a red, pruritic lesion on her left labium over the past 7 months. On physical examination, this rough, scaly lesion is 0.4 x 0.9 cm. The perineum appears normal; there is no lymphadenopathy, and there are no rectal lesions. A Pap smear shows no abnormal findings. The lesion is excised and on microscopic examination shows large atypical cells lying singly or in small clusters within the epidermis. These cells have abundant cytoplasm that stains with periodic acid-Schiff (PAS). What is the most likely diagnosis? A. Condylomata acuminata B. Extramammary Paget disease C. Lichen sclerosus et atrophicus D. Lichen simplex chronicus E. Vulvar intraepithelial neoplasia B

A 42-year-old woman has had menometrorrhagia for the past 2 months. She has no history of prior irregular menstrual bleeding, and she has not yet reached menopause. On physical examination, there are no vaginal or cervical lesions, and the uterus appears normal in size, but there is a right adnexal mass. An abdominal ultrasound scan shows the presence of a 7-cm solid right adnexal mass. Endometrial biopsy shows hyperplastic endometrium, but no cellular atypia. What is the most likely lesion that underlies her menstrual abnormalities? A. Corpus luteum cyst B. Endometrioma C. Granulosa-theca cell tumor D. Mature cystic teratoma E. Metastasis C

54. A 62-year-old obese, nulliparous woman has an episode of vaginal bleeding, which produces only 5 mL of blood. On pelvic examination, there is no enlargement of the uterus, and the cervix appears normal. A Pap smear shows cells consistent with adenocarcinoma. Which of the following preexisting conditions is most likely to have contributed to the development of this malignancy? A. Adenomyosis B. Chronic endometritis C. Endometrial hyperplasia D. Human papillomavirus infection E. Use of oral contraceptives C

اذا سالكم ياهو اكثر كانسر شائع بالفيميل بعد استعمال لقاح hpv فالجواب اندومتريم اذا سال ياهو جان الاكثر قبل لا نستعمل لقاح الHPV اختار السرفايكل