Physio & Pharma & Bio (64) 💗
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قناة الفارما والفسيو والبايو د.شريف د.وسام د. الصاوى الدفعة ٦٤ طب المنصورة
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شبابنا الجميل، انتوا لسه راجعين من الاجازة ، طبيعى تبقى حاسس بالملل والمذاكرة تقيلة وكل ده،
مش مطلوب منك تعمل كل حاجة بيرفكت، لا تفهم ١٠٠% ولا تحفظ ولا تحل ،
انت لو سمعت ده انجاز، بس متراكمش
الفسيولوجى تقيل شوية السيمستر ده،
اللى متفهموش من اول مرة هيبقى أسهل ف المراجعة متقلقش ومتحملش الهم بدرى ،
الدنيا مش ناقصة 🤣
| 2 |  ال FF = GFR ÷ RPF
GFR= RPF × FF
معلش كان خطأ بسيط ف الدياجرام للقانون الثانى عملتها قسمة بدل ضرب | 208 |
| 3 | تم رفع المحاضرة الاولى بايو رينال :
✔️ شرح
✔️ رابيد
✔️ ام سى كيو
ع التطبيق ياشباب ❤️👌 | 219 |
| 4 |  مستمرين فى حجز كورسات سمستر 3
من خلال :
🔴 سنتر سيركل :
يوميا من 10 ل 4
🔴 او من خلال فودافون كاش :
التواصل ع واتساب 01098198182 | 145 |
| 5 | Voice message | 439 |
| 6 |  +1No text... | 437 |
| 7 | 🟥🟥Regulation of Renal Blood Flow and GFR:
✅️Intrinsic (Autoregulation):
Maintains near-normal RBF/GFR from 80–180 mmHg arterial pressure
(major site: afferent arteriole).
🟣🟣Mechanisms:
🔴🔴🔴Myogenic: vascular smooth muscle contraction/relaxation in response to pressure changes.
🔴🔴🔴Tubuloglomerular feedback: macula densa senses NaCl, secretes adenosine to constrict or PGI2 to dilate afferent arteriole, and adjust renin release.
✅️Extrinsic Regulation
🟣🟣Neural: Sympathetic stimulation
🔴🔴🔴via α1: vasoconstriction
🔴🔴🔴and β1 receptors: causes and renin release.
🟣🟣Humoral:
🔴🔴🔴Vasoconstrictors include catecholamines, angiotensin II, ADH, endothelin;
🔴🔴🔴vasodilators include nitric oxide, dopamine, bradykinin, prostaglandins. | 437 |
| 8 | 🟥🟥Renal Blood Flow and Filtration
✅️Total renal blood flow:
about 1200 mL/min
(20-22% of cardiac output).
✅️Renal plasma flow (RPF):
660 mL/min.
✅️Glomerular filtration rate (GFR):
125 mL/min (about 20% of RPF is filtered).
✅️Filtration fraction (FF):
GFR/RPF, typically 20%.
🟣🟣Cortex receives the highest flow; medulla receives much less | 371 |
| 9 | 🟥🟥Juxtaglomerular Apparatus (JGA)
✅️Components:
🟣Macula densa: act as Chemoreceptors, monitors NaCl concentration in the distal convoluted tubule (DCT).
🟣Juxtaglomerular (JG) cells: in the wall of the afferent arteriole, secrete renin and act as baroreceptors.
🟣Extraglomerular mesangial (lacis) cells: supportive and phagocytic functions.
✅️Functions:
🟣🟣Chemoreceptors: detect NaCl in DCT; stimulate secretion of PGI2 (vasodilator) and adenosine (vasoconstrictor).
🟣🟣Baroreceptors: detect changes in wall tension due to blood pressure alterations, trigger renin release. | 375 |
| 10 | 🟥Nephron Types:
✅️Cortical nephrons:
85%, located in the outer 2/3 of the cortex, have short loops of Henle, main function is urine formation.
✅️Juxtamedullary nephrons:
15%, located in the inner 1/3 of the cortex, long loops of Henle dipping deep into the medulla, major role in urine concentration. | 363 |
| 11 | Major Kidney Functions
✅️Maintain constancy of the internal environment (ECF): regulate total body water, tissue fluid osmolarity, electrolytes (Na+, K+, Ca++), and pH.
✅️Metabolic functions: gluconeogenesis during fasting, hormone degradation (insulin, glucagon).
✅️Excretion: removal of metabolic wastes (urea, uric acid, creatinine) and foreign substances (drugs, toxins).
✅️Endocrine functions:
🟣🟣Secretion of erythropoietin (stimulates RBC production). Decrease cause anemia.
🟣🟣Release of renin (activates renin-angiotensin system).
🟣🟣Activation of vitamin D (1,25 dihydroxycholecalciferol): ca homeostasis.
🟣🟣Production of prostaglandins | 392 |
| 12 | 🚨🚨 المحاضرة الأولى فسيو الرينال:
✅️ Part 1
✅️ Part 2
✅️ Part 3
✅️Revision
📌📌 PDF الشرح
📌📌 PDF الدياجرامات
📌📌PDF ال MCQ
✅️ النظام | 682 |
| 13 | Renal 1 - MCQs.pdf | 405 |
| 14 |  🚨🚨مراجعة المحاضرة الأولى فسيو رينال🚨🚨 | 417 |
| 15 | ✅️ كدا يا صديقى معاك ٣ أجزاء للمحاضرة الاولى، معلش اول محاضرتين ف الرينال طوال شوية ،
بس معاك شوية دياجرامات ف الرينال تسهل عليك جدا ودى اللى شارحين عليها👊🏻
وعامة السيمستر دا فيه الفسيولوجى من ابو جد الجد، والفهم فيه مهم❤️
وهتلاقينى معاك مظبطهولك ان شاءالله بفضل الله اولا واخيرا❤️ | 432 |
| 16 |  ✅️Physio Renal 1: Part 3 🤣🤣
(Regulation of RBF) | 440 |
| 17 |  ✅️Physio Renal 1: Part 2
(Types of nephrons & JGA) | 475 |
| 18 |  ✅️Physio Renal 1: Part 1
(Functions & Anatomy of the kidney) | 480 |
| 19 | 🚨🚨PDF المحاضرة الأول🚨🚨 | 487 |
| 20 | 🚨🚨ملف شرح ودياجرامات المحاضرة الأولى - فسيو الرينال🚨🚨 | 486 |
