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*Cholera*
⏭️Cholera is an acute diarrheal disease caused by Vibrio cholerae.
⏭️• I.P.- 1-2 days
⏭️First step in epidemic of cholera: Verification of diagnosis
📝 Stool appearance of cholera: “Rice watery stool”
📝Chemoprophylaxis of cholera: Tetracycline 500mg BID for 5
days.
*🔖Drug of choice for cholera:*
💿Adults: Doxycycline 300 mg stat.
*️⃣ Children: Azithromycin 20 mg/kg, single dose
*️⃣Pregnant Female: Azithromycin 1 gm, single dose
Common Nerve Injuries
⌚ *Wrist drop – Radial nerve*
👠 *Foot drop – Either common peroneal nerve or sciatic nerve*
✊🏻 *Claw hand – Ulnar nerve*
🤞 *Paraesthesia of thumb, index and middle finger – Median nerve*
💪 *Numbness on superior aspect of upper arm just below shoulder joint – Axillary nerve*
👢 *Fibular neck fracture – Common peroneal nerve*
🦵 *Femur neck fracture or Acetabular fractures – Sciatic nerve*
🤰 *Fracture of humeral shaft – Likely Radial nerve*
🤰🏾 *Fracture of humeral Neck – Likely Axillary nerve*
🏓 *Monteggia fracture – Radial nerve*
🧤 *Paraesthesia and impaired sensation in both hands (glove distribution) – Peripheral neuropathy*
🔷Antara Programme 🔷
▪️Injectable contraceptive
▪️MPA (medroxyprogesterone
acetate)
▪️Dose - 150mg IM, every 3 months
▪️First dose can be taken :
🔸Anytime after regular menstruation (5th day of Menstrual cycle)
🔸After 6 weeks of delivery
🔸Immediately after abortion
🔷Other Injectible Contraceptive
🔹DMPA
▪️Depot Medroxy Progesterone Acetate
▪️Dose 150 mg (IM)
▪️Site -Gluteus Maximus
▪️Effectiveness -3 Month
🔹 NET-EN
▪️Norehisterone Enantate
▪️200 mg (IM )
▪️Site - Gluteus Maximus
▪️Effectiveness -3 Month
🔹DMPA SC 104 mg
▪️New lower dose formulations DMPA ( depo subQ provera 104 also called DMPA SC )
Route - SC
Site - Upper thigh or Abdomen
▪️Effectiveness -3 month
🔹 Mechanism of Action
🔸Inhibition of ovulation
🔸Cervical mucus thickening
🔸Endometrial atrophy preventing Implantation
▪️Contraindications
🔸Unexplained vaginal bleeding
🔸Stroke or severe diabetes
🔸Breast cancer (past or present)
🔸Active hepatitis or liver tumor
🔸A desire for rapid return of fertility
▪️Disadvantages
🔸Menstrual irregularities (light / heavy bleeding /amenorrhea)
🔸Slight weight gain
🔸No protection against sexually transmitted diseases
🔸A slight loss in bone mineral density during the first two years of use.
🔷Antara Programme 🔷
▪️Injectable contraceptive
▪️MPA (medroxyprogesterone
acetate)
▪️Dose - 150mg IM, every 3 months
▪️First dose can be taken :
🔸Anytime after regular menstruation (5th day of Menstrual cycle)
🔸After 6 weeks of delivery
🔸Immediately after abortion
🔷Other Injectible Contraceptive
🔹DMPA
▪️Depot Medroxy Progesterone Acetate
▪️Dose 150 mg (IM)
▪️Site -Gluteus Maximus
▪️Effectiveness -3 Month
🔹 NET-EN
▪️Norehisterone Enantate
▪️200 mg (IM )
▪️Site - Gluteus Maximus
▪️Effectiveness -3 Month
🔹DMPA SC 104 mg
▪️New lower dose formulations DMPA ( depo subQ provera 104 also called DMPA SC )
Route - SC
Site - Upper thigh or Abdomen
▪️Effectiveness -3 month
🔹 Mechanism of Action
🔸Inhibition of ovulation
🔸Cervical mucus thickening
🔸Endometrial atrophy preventing Implantation
▪️Contraindications
🔸Unexplained vaginal bleeding
🔸Stroke or severe diabetes
🔸Breast cancer (past or present)
🔸Active hepatitis or liver tumor
🔸A desire for rapid return of fertility
▪️Disadvantages
🔸Menstrual irregularities (light / heavy bleeding /amenorrhea)
🔸Slight weight gain
🔸No protection against sexually transmitted diseases
🔸A slight loss in bone mineral density during the first two years of use.
202309300941095551022finaladvEnglishforgroupB_Cregularpostsseptember23.pdf2.44 KB
👉 Oligomenorrhea= irregular, infrequent menstrual cycle more than 35 day in duration
👉 Polymenorrhoea = Regular and frequent menstrual cycle less than 21day in duration.
👉 Menorrhagia= Excessive menstrual blood loss more than 80 ml with normal duration of cycle.
👉 Mettorhagea = Excessive irregular menstrual cycle with normal amount of menstrual blood loss.
👉 Meno-mettorhagea = Excessive irregular menstrual cycle with excessive amount of blood loss
👉 Hypomenorrhoea= decrease amount of blood loss
Less than 20 ml and less than 2day in duration.
👉 Dysmenorrhea= Excessive painful menstrual bleeding with normal duration of menstrual cycle and normal amount of menstrual blood loss.
👉 Cryptomenorrhoea = present of menstrual like symptoms but absence of menstrual bleeding
{Most common course- Imperforate hymen}
*SUMMARY OF CPR :*
∆ PULSE ASSESSMENT:
• ADULT - CAROTID
• CHILDREN (1-8YR) - CAROTID / FEMORAL
• INFANT (UPTO 1 YR) - BRACHIAL
*∆ COMPRESSION METHOD:*
• ADULT - TWO HAND
• CHILDREN - TWO HAND / ONE HAND
• INFANT - TWO THUMB / TWO FINGER
*∆ COMPRESSION DEPTH :*
• ADULT - 2 INCH
• CHILDREN - 2 INCH
• INFANT - 1.5 INCH
*∆ COMPRESSION RATIO:*
1 RESCUER :
• ADULT - 30:2
• CHILDREN - 30:2
• INFANT - 30:2
2 RESCUER :
• ADULT - 30:2
• CHILDREN - 15:2
• INFANT - 15:2
Check your
NORCET-05 Mains Exam City
Click here 👇🏻
https://norcet5.aiimsexams.ac.in/
##Important points for NORCET:-)
*.Pulmonary Tuberculosis (PTB)* —low-gradeafternoon fever.
*. *Pneumonia* —rust-colored sputum.
*.Asthma*—wheezing on expiration.
*.Emphysema*—barrel chest.
*.Kawasaki Syndrome*—strawberry tongue.
*.Pernicious Anemia*—red beefy tongue.
*.Down syndrome*—protruding tongue.
*.Cholera*—rice-watery stool and washer woman’s hands (wrinkled hands from dehydration).
*.Malaria*—stepladder like fever with chills.
*.Typhoid*—rose spots in the abdomen.
*.Dengue*—fever,rash, and headache. Positive Herman’s sign.
*.Diphtheria*—pseudomembrane formation.
*.Measles*—Koplik’s spots (clustered white lesions on buccal mucosa).
*.Systemic Lupus Erythematosus*—butterfly rash.
*.Leprosy*—leonine facies (thickened folded facial skin).
*.Bulimia*—chipmunk facies (parotid gland swelling).
*.Appendicitis*—rebound tenderness at McBurney’s point.
Rovsing’s sign (palpation of LLQ elicits pain in RLQ). Psoas sign (pain from flexing the thigh to the hip).
*.Meningitis*—Kernig’s sign (stiffness of hamstrings causing inability to straighten the leg when the hip is flexed to 90 degrees),
Brudzinski’s sign (forced flexion of the neck elicits a reflex flexion of the hips).
*.Tetany*—hypocalcemia, [+] Trousseau’s sign; Chvostek sign.
*.Tetanus*— Risus sardonicus or rictus grin.
*.Pancreatitis*—Cullen’s sign (ecchymosis of the umbilicus), Grey Turner’s sign (bruising of the flank).
*.Pyloric Stenosis*—olive like mass.
*.Patent Ductus Arteriosus*—washing machine-like murmur.
*.Addison’s disease*—bronzelike skin pigmentation.
*.Cushing’s syndrome*—moon face appearance and buffalo hump.
*.Grave’s Disease (Hyperthyroidism)*—Exophthalmos(bulging of the eye out of the orbit).
*.Intussusception—Sausage*-shaped mass.
*.Multiple Sclerosis*—Charcot’s Triad: nystagmus, intention tremor, and dysarthria.
*.Myasthenia Gravis*—descending muscle weakness, ptosis (drooping of eyelids).
*.Guillain-Barre Syndrome*—ascending muscles weakness.
*.Deep vein thrombosis (DVT)*—Homan’s Sign.
*.Angina*—crushing, stabbing pain relieved by NTG.
*.Myocardial Infarction (MI)*—crushing, stabbing pain radiating to left shoulder, neck, and arms. Unrelieved by NTG.
*.Parkinson’s disease*—pill-rolling tremors.
*.Cytomegalovirus (CMV) infection*—Owl’seye appearance of cells (huge nucleus in cells).
*.Glaucoma*—tunnel vision.
*.Retinal Detachment*—flashes of light, shadow with curtain across vision.
*.Basilar Skull Fracture*—Raccoon eyes (periorbital ecchymosis) and Battle’s sign (mastoid ecchymosis).
*.Buerger’s Disease*—intermittent claudication (pain at buttocks or legs from poor circulation resulting in impaired walking).
*.Diabetic Ketoacidosis*—acetone breathe.
*.Pregnancy Induced Hypertension (PIH)*—proteinuria, hypertension, edema.
*.Diabetes Mellitus*—polydipsia, polyphagia, polyuria.
*.Gastroesophageal Reflux Disease (GERD)*—heartburn.
*.Hirschsprung’s Disease (Toxic Megacolon)*—ribbon-like stool.
*.Sexual Transmitted Infections:*
*.Herpes Simplex Type Il*—painful vesicles on genitalia
*.Genital Warts*—warts 1-2 mm in diameter.
*.Syphilis*—painless chancres.
*.Chancroid*—painful chancres.
*.Gonorrhea*—green, creamy discharges and painful urination.
*.Chlamydia*—milky discharge and painful urination.
*.Candidiasis*—white cheesy odorless vaginal discharges.
*.Trichomoniasis*—yellow, itchy, frothy, and foul-smelling vaginal discharges.
*Normal value of important subastance in blood.*
*Glucose 100~120 mg/dl*
*creatinine 0•5~1•5mg/dl*
*cholesterol 200mg/dl*
*plasma protein 6•4~8•3g/dl*
*bilirubin 0•5~1•5mg/dl*
*copper 100~200mg/dl*
*iron 50~150micro g/dl*
*calcium 9~11mg/dl*
*sodium 135~145mEq/l*
*potassium 3•5~5mEq/l*
*magnesium 1•5~2mEq/l*
*chloride 100~110mEq/l*
*Bicarbonate 22~26mEq/l*
*total protein 7•3g/dl*
*serum albumin 4•7g/dl*
*serum globulin 2•3g/dl*
*fibrinogen 0•3g/dl*
*A/G ratio 2•1*
*IgG 1000mg/dl*
*IgA 200mg/dl*
*IgM 120mg/dl*
*IgD 3mg/dl*
*IgE 0•05mg/dl*
ANTIDOTE AND DRUG OF CHOICE PROPHYLAXIS(Dx/Px):-
1.Drug for PCM poisoning :- N acetylecystine (mucomyst)
2. DOC for Acute Asthma:- Salbutamol
3.DOC for Chronic Asthma:- Salmetrol
4.Drug of choice for bipolar disorder:- Lithium
5.Drug of choice for mania:- Lithium
6.Drug of choice for acute mania:-Haloperidol
7.Drug of choice for chronic mania:-Lithum
8.Drug of choice for hyperkalamia:- Kayxalate/sodium natropuroside/insuline+dextrose
9.Drug of choice for Ketoacidosis:- Insuline+dextrose
10.Prophylaxis for Asthma:-Montalucast
11.Drug for Digitalis Toxicity:-Digibind
12.Drug of choice for Acute migraine:-Sumatripatan
13 Drug of choice for ADHD:-Methylphenidate(Amphetamine)
14.Drug of choice for Alzeihmers disease:-Tacrine/donepzil/Rivastigmine
15.Drug of choice for Myasthenia gravis:-Neostigmine
16.Drug of choice for Anaphylactic Shock:-Adrenaline
17.Drug of choice for Hyperthyroidism in pregnancy/Lactation:-Propylthiouracil
18.Drug of choice for Atonic Seizures:-Sodium valproate
19.Drug of choice for Febrile Seizures:-Diazepam
20.Antidote for Aspirine poisoning:-Sodium bicarbonate
21.Antidote for organophosphate poisoning:-Atropine
22.Drug of choice for Central Diabetic Insipidus:-Vasoprassin/desmopressin
23.DOC for Chemotherapy induced vomiting:-Ondasteron
24.DOC for chloroquine resistant malaria:-Quinine
25.DOC for cholera:Tetracycline
26.Antidote for Benzodiazapine poisoning:-Flumazenil
27.Antidote for Barbiturate poisoning:-Sodium bicarbonate
28.Antidote for Atropine poisoning:-Physostigmine
29.DOC for Chese reaction:-Phentolamine
30.DOC for Acute Gout:-Indomethacin
31.DOC for Chronic Gout:-Allopurinol
32.DOC for complicated Malaria:-Artesunate
33.Antidote for Cyanide poisoning:-Amyl nitrate
34.DOC for Depression:-Any of SSRI drug(Citalopram,Escitalopram,Fluoetine,Paroxetine,Sertraline,Vilazodone)
35.DOC for disease modifying anti Rheumatic drug(DMARD):-Methotrexate
36.DOC for drug induced parkinson disease:-Benzhexol
37.Choice of Muscle relaxant for Endotracheal intubation:-Succinylcholine
38.Choice for Relaxant for ECT:-succinylcholine
39.Treatment of choice for severe Depression:-ECT
40.DOC for Enteric Fever:-Ceftrixone
41.DOC for Epilepsy in pregnancy:-Lamotrigine
42.Antidote for Fibrinolytics:-Aminocaproic acid
43.DOC for BPH(Benign prostate hypertrophy):-Prozosin
44.Antidote for Heparine Toxicity:-Protamine sulphate
45.prophylaxis for herpes:-Acyclovir
46.prophylaxis for rheumatic fever:-Benzathaine penicilline
47.prophylaxis for MI:-Asprine
48.DOC for Malaria:-Chloroquine
49.DOC for hypertensive emergency:-Sodium nitroprusside
50.DOC for hypertension in pregnancy:-Lobetalol
51.DOC for Eclampsia:-Mgso4
52.DOC for Hypothyroidism:-Levothyroxin
53.DOC for hypovolemic Shock:-IV fluids
54.Antidote for Iron toxicity :-Desferoxamine
55.DOC for Methanol poisoning:-Fomepizole
56.DOC FOR Methicillin resistant staphylococcus aureus :- Vencomycin
57.Mydriatic of choice in Adults:-Tropicamide
58.Mydriatic of choice in children:-Atropine
59.DOC for syphillis:-Benzathine penicilline
60.DOC for noctural enuresis :- Desmopressin/imipramine
61.DOC for obsessive compulsive disorders:-SSRI
drug(Citalopram,Escitalopram,Fluoetine,Paroxetine,Sertraline,Vilazodone)
62.Antidote for Opiod poisoning:-Nalaxone
63. DOC for oral hypoglycemic drug in obese :- metformine
64.DOC for oral hypoglycemic drug in thin:-Sulfonylureas
65.DOC for cardiogenic Shock:-Dobutamine
