Nucleus medical media

Xanthelasma There are well demarcated, yellow plaques on the medial aspect of the bilateral eyelids, which is consistent with xanthelasma. Xanthelasma consists of cutaneous lipid deposits and is a common finding in patients with hypercholesterolemia

Cri-du-chat syndrome (cat cry syndrome) Definition: rare syndrome caused by a chromosome 5 aberration  [11][12] Epidemiology: sex distribution: ♀ > ♂ (2:1) Etiology: microdeletion of the short arm at chromosome 5 (46,XX,5p- or 46,XY, 5p‑) Clinical features Cat-like, high-pitched crying in affected infants Congenital heart defects, e.g., VSD Microcephaly Intellectual disability (moderate to severe) Single palmar crease Dysmorphic facial features Moon facies Widely spaced eyes Epicanthal folds Broad nasal bridge Downward-slanting palpebral fissures Skeletal abnormalities