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Q1/ Ewing sarcoma characteristically shows strong, diffuse membranous staining with which of the following immunohistochemical stains?
A. CD99
B. Desmin
C. FLI1
D. S100 protein
Q2/ A 12 year old boy injured his left arm while playing football. Radiograph demonstrated an aggressive lesion in the mid diaphyseal region of his left humerus with permeative appearance and lamellated periosteal reaction (onion skin). Biopsy shows a small round blue cell tumor. What is the most likely diagnosis?
A. Chondrosarcoma
B. Ewing sarcoma
C. Lymphoma
D. Osteosarcoma
Osteosarcoma
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مش موجودات في الموقع
A 56 year old man had a 6.2 cm sacral mass. The microscopic image is from the resection specimen. Which of the following is true about this entity?
A. The tumor has a very low metastatic rate
B. The tumor has the capacity to dedifferentiate.
C. The tumor is probably negative for EMA
D. These tumors are very responsive to chemotherapy
E. These tumors usually occur in the extremities
The best diagnosis is
A. Chondroblastoma
B. Chondroblastoma-like osteosarcoma
C. Chondromyxoid fibroma
D. Giant cell tumor of bone
Q/ Which of the following is most likely the correct diagnosis?
A. Central atypical cartilaginous tumor / chondrosarcoma, grade 1
B. Chondromyxoid fibroma
C. Clear cell chondrosarcoma
D. Enchondroma
E. Osteochondroma
Which of the following is true about the epidemiology of osteochondromas?
A. Congenital lesions are relatively common
B. Female predominance
C. Most lesions arise in long bones
D. Most common in the elderly
E. Multiple lesions are more common
Which of the following is true regarding secondary chondrosarcoma?
A. Most common subtype is clear cell chondrosarcoma
B. Patients with multiple osteochondromas have a higher overall risk of developing chondrosarcoma.
C. Risk of malignancy in patients with multiple hereditary exostosis is near 50%
D. Risk of malignancy in solitary osteochondromas is high
