Pharmacology. 48

من فضلكم حالة مستعجلة، يا ريت اي حد عنده قناة يدير اعادة توجيه بلكي يحقها حد يقدر يساعده💔

نبي نسالك صاح الي ماخشش لي امتحان الدور الاول مايقدرش ايخش ع الدور الثاني الا بي عذر

لجنة 15دكتورة صفاء البدري الكرت الوردي تعرفي الافكسي انواع اagonist وانواع antagonist شن اهم 3 حاجات ايدير فيهن ال Atropine وتبي الاكشن انواع الا اديرنرجك رسبتور وكل واحد تبي اهم دواء Antagonist و agonist ليش نستخدمو في alph. Agonist ليش الanti fungal مانستخدموش فيه مع اي دواء عنده D-D introduction الكرت الابيض ادوية PU وتبي مثال ع كل نوع الangina تبي العلاج 2nd 1st 3rd انواع diuretic عطتني كيس لو شايب جاك و عنده osteoporosis و p.edema شن نعطيه تبي الاسم الاخر لي سبيرولولكتون ولشن يستخدم وشن اشهرحاجتين ايسببهن شن ايدير ثيازايد الhyperthyroidism عند من ايسير المهم نستحق ففففففل مارك ع المطحنه😂😂💜

لما كنت نقول كل حد وبخته ماصدقتونيش😂😂😂

وهكي نكونو ختمنا رحلتنا فالفارما وعقاب ختام رحلة ثالثه 🥺💜 ويارب تكون هذي الخاتمة للجميع وماحد يستحق يقراها مره ثانيه 🤍 ربي ايوفقكم فالمايكرو ونخشو كلنا ال رابعه 🤍 سامحوني ع اي تقصير او تاخير او اي مشكله صارت بسبب القناة لان والله كانن حاجات خارج إرادتي 😊

احفظوها زي اسمكم HTN with BPH..... Alpha 1blocker(prazosin) HTN in pregnancy...Alpha2 agonist (alpha methyl dopa) HTN with DM... ACEi HTN with Renal proplem... ACEi HTN with H.F..... ACEi HTN with Coronaryartery disease..Beta blocker HTN in elderly... Thiazide HTN without complication... Thiazide initial HTN..... Thiazide H. F with SVT.... Digoxin prinzmetal angina..... CCB Acute pulmonary edema... Furosemide H. F with Liver cirrhosis or Nephrotic syndrome,.... we add Spirinolactone

#Respiratory_pharma ● E/W theophylline is considered a 2nd or 3rd  line drug in asthma 1.requiring drug monitoring 2. Narrow safety margin. 3. drug interactions

#CVS_Pharma ● E/W Beta blockers C/I in DM ? They mask symptoms of hypoglycemia&  delay recovery from hypoglycemia

#GIT_Pharma ● E/W Al hydroxide and Mg are most commonly used antacid? - b/c no CO2 release or systemic alkalosis - used combined to neutrilize effects of each other( AL cause constipation & Mg cause diarrhea) ● E/W antacids should be cautiously used in elderly & renal impairment? - bc chelate phosphates > induce osteomalacia, encephalopathy Alzheimer, cns depression

#antiGOUT ■ E/W DMARDs are combined with NSAIDs or Glucocorticoids = - b/c their onset of effect is delayed (2 weeks to 6 months )

#antiGOUT ■ E/W Allopurinol given once daily and it has short half life = - b/c it's metabolized into alloxanthine which has capacity to inhibit Xanthine oxidase for 15-18 hrs

#CNS_Pharma ■ E/W BARBs contraindicated in pt with Acute intermittent Porphyria = - b/c increase porphyrin by stimulating aminolevulinic acid (ALA) synthase.

#CNS_Pharma ■ E/W BZDs & BARBs causing Hangover (Tiredness after waking) = - b/c they are redistributed and accumulated in body fat

#CNS_Pharma ■ E/W BARBs used in kernicterus (neonatal jaunice) = - b/c it's enzyme inducer, ⬆️ Bilirubin metabolism

#CNS_Pharma ■ E/W Local Anesthesia not given to inflammed area = - due to low PH in this area lead to ⬆️ ionized form of LA = ⬇️ its action

#CNS_Pharma ■ E/W Lithium is contraindicated with diuretics = - b/c diuretics cause Na depletion leads to increased Lithium reabsorption ➡️ Li toxicity

#CNS_Pharma ■ E/W use of phenytoin is limited = - due to its troublesome kinetics resulting in unpredictable serum levels due to = - Irregular bioavailability - Saturation kinetics (conc. may ⬆️ to toxic levels) - Drug interactions

#CNS_Pharma ■ E/W Phenobarbital & BZDs not 1st choice for epilepsy = - b/c of sedation and tolerance limit their use

#CNS_Pharma ■ E/W Amantadine (antiviral) used in ttt of Parkinson = - b/c of its effect to increase release of dopamine and decrease its uptake

#CNS_Pharma ■ E/W non-selective MAO inhibitors ara contraindicated with L.dopa = - b/c they causes severe hypertension