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3 428
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A 55-year-old patient with (CML) has failed treatment with imatinib. Genetic testing reveals the presence of the T315I mutation in the BCR-ABL gene. Which of the following agents is the most appropriate next-line therapy for this patient?
3 428
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Which of the following tyrosine kinase inhibitors is most commonly associated with the severe side effect of pleural effusion?
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Which of the following is an appropriate prophylactic strategy to prevent tumor lysis syndrome in high-risk patients?
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A 4-year-old boy is newly diagnosed with (ALL), the most common leukemia in children. He is started on induction chemotherapy. Lab tests show hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia. What is the most likely diagnosis?
3 428
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A 65-year-old patient with relapsed AML is found to carry an IDH2 gene mutation. He is otherwise stable and eligible for targeted therapy. Which of the following agents is specifically indicated for his condition?
3 428
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A 72-year-old patient with relapsed (AML) is evaluated for further treatment. He has multiple comorbidities , making him unfit for intensive chemotherapy. Which of the following treatment options is most appropriate in this patient?
3 428
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1- Midostaurin for FLT3 mutation as (induction chemotherapy )
2- Gilteritinib for FLT3 mutation as (relapsed chemotherapy )
3 428
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A 60-year-old patient with relapsed acute myeloid leukemia (AML) is found to have an FLT3-ITD mutation on molecular testing. Which of the following is the most appropriate targeted therapy in this setting?
3 428
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A 45-year-old man is newly diagnosed with acute myeloid leukemia (AML). Molecular testing reveals a FLT3 mutation. Which of the following agents should be added to his induction chemotherapy regimen?
3 428
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A 55-year-old patient is diagnosed with relapsed acute myeloid leukemia (AML). Genetic testing reveals a mutation in the IDH1 gene. Which of the following is the most appropriate targeted therapy for this patient?
3 428
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