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-------------------------------------------------------------- 𝗦𝗞𝗘𝗟𝗘𝗧𝗔𝗟 𝗠𝗨𝗦𝗖𝗟𝗘 ❖ Closely associated with the skeletal components of the body. ❖ Primarily involved in locomotion and body posture. Skeletal muscle ⇓ Muscle bundles/Fascicles ⇓ Fascia (collagenous connective tissue) ❖ Each muscle bundle contains a number of muscle fibres. ❖ Muscle fibre is a syncitium (sarcoplarm contains many nuclei). ❖ Endoplasmic reticulum, i.e., sarcoplasmic reticulum of muscle fibre is the store house of calcium ions. ❖ Each muscle fibre has many parallelly arranged myofibrils/ myofilaments. ❖ Each myofibril has dark and light bands due to actin and myosin distribution that establish striated appearance.

------------------------------------------------------ 𝗙𝗹𝘂𝗶𝗱 𝗠𝗼𝘀𝗮𝗶𝗰 𝗠𝗼𝗱𝗲𝗹 𝗼𝗳 𝗣𝗹𝗮𝘀𝗺𝗮 𝗠𝗲𝗺𝗯𝗿𝗮𝗻𝗲 ❖ This model was proposed by Singer and Nicolson in 1972 which is widely accepted. ❖ It described protein as ice bergs in a sea of lipids. ❖ According to this model, the quasi-fluid nature of lipid enables lateral movement of proteins within the overall bilayer. This ability to move within the membrane is measured as its fluidity. 𝗧𝗵𝗲 𝗳𝗹𝘂𝗶𝗱 𝗻𝗮𝘁𝘂𝗿𝗲 𝗼𝗳 𝘁𝗵𝗲 𝗺𝗲𝗺𝗯𝗿𝗮𝗻𝗲 𝗶𝘀 𝗶𝗺𝗽𝗼𝗿𝘁𝗮𝗻𝘁 𝗳𝗼𝗿 ❖ Cell growth ❖ Formation of intercellular junctions ❖ Secretion ❖ Endocytosis ❖ Cell division

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