Pathology - Malek

50. How does obstructive uropathy decrease concentration ability of kidneys? A. Ischemia to papilla B. Venous edema C. Glomerular edema D. Dilation of calyces

46. Death from fulminant hepatitis A. Hepatitis A B. Hepatitis B C. Hepatitis C D. Hepatitis D E. Hepatitis E 47. Post transfusion hepatitis commonly caused by? A. Hepatitis B B. EBV C. CMV D. Herpes 48. RCC associated with poor prognosis? A. Clear RCC B. Papillary Renal Cell Carcinomas C. Chromophobe RCC D. Sarcomatoid RCC 49. Solitary thyroid nodule, cold on radioiodine study? A. Hashimoto B. Non neoplastic C. Neoplastic D. MNG

39. Case about osteosarcoma but forgot it, probably asking about the fact that it produces true bone. 40. Key feature of ulcerative colitis? A. Involve the rectum and spread proximally B. Pseudopolyps C. Fistulas 41. Feature of crohn's disease that favors formation of fistula A. Deep ulcers 42. Case about mature teratoma 43. Regarding liver adenoma? A. The tumor is yellow-tan, well-demarcated nodules, up to 30 cm in diameter 44. A 38-year-old man presents with jaundice and pruritus. Laboratory examination reveals markedly elevated serum levels of alkaline phosphatase. Antinuclear antibodies are not present, but a serologic test for p-ANCA is positive. An endoscopic retrograde cholangiopancreatography reveals "beading" of the bile ducts. A liver biopsy specimen showed that many of the bile ducts to be surrounded by marked collagenous connective tissue deposition with epithelial atrophy and luminal narrowing. What is the best diagnosis? A. Autoimmune hepatitis B. Chronic active hepatitis C. Chronic persistent hepatitis D. Primary biliary cirrhosis E. Primary sclerosing cholangitis 45. Which antibody is associated with primary biliary cholangitis? A. Antimitochondrial B. Anti smooth muscle

38. Case of multiple expanding cysts of both kidneys and liver cyst (with more details related to ADPKD) A. Recessive B. Associated with cerebral aneurysm

37. Diffuse effacement of lvmph node A. ALL

36. Finding of cml A. Small multilobed megakaryocytes B. Transition from chronic to blastic phase 10%

35. Cirhhosis as a late manifestation? A. a 1-antitrypsin defeciency B. Drug induced C. Hemochromatosis D. Autoimmune

34. Nasal mass, rich blood supply associated with what hormone? A. Prolactin B. Testosterone C. Estrogen D. Growth hormone E. Thyroxine

33. Chronic hoarsness. Mass removed from larynx. Histopathological examination shows dilated blood vessels with hyalinization of the stroma. A. Laryngeal nodule B. Laryngeal papilloma

32. Celiac disease microscopical finding A. Eosinophils B. Crypts hypotrophy

30. Child with hemarthrosis and joint mobility issues, with <1% FVIII and bleeding tendency. Presnets with emergency attack of bleeding, what is the first line management? A. recombinant FVIII infusion B. vasopressin (DDAVP) 31. Complication of ABO incompatibility represent ? A. 10% B. 30% C. 60% D. 70% E. 90%

29. A 25-year-old man has a 5-year history of celiac sprue. Four days after a mild upper respiratory infection, he begins passing dark red-brown urine. The dark urine persists for the next 3 days and then becomes clear and yellow, only to become red-brown again 1 month later. There are no remarkable findings on physical examination. Urinalysis shows a pH of 6.5; specific gravity, 1.018; 3+ hematuria; 1+ proteinuria; and no glucose or ketones. Microscopic examination of the urine shows RBCs, but no WBCs, casts, or crystals. A 24- hour urine protein level is 200 mg. A renal biopsy specimen from the glomeruli of this patient is most likely to show which of the following alterations? A. Diffuse cellular proliferation and basement membrane thickening B. Granular staining of the basement membrane by anti-IgG antibodies C. Mesangial IgA staining by immunofluorescence D. Subepithelial electron-dense deposits E. Thrombosis within the glomerular capillaries

28. A 33-year-old female has had a cervical lymphadenopathy. Biopsy of one lymph node reveal thick bands of fibrous connective tissue with intervening lymphocytes, plasma cells, eosinophils. macrophages, and occasional Reed-Sternberg cells. The subtype her Hodgkin disease is? A. Lymphocyte predominant B. Mixed cellularity C. Lymphocyte depleted D. Nodular lymphocyte predominant E. Nodular sclerosis

The most common type of cervical cancer is? A. Keratinizing squamous cell carcinoma B. Nonkeratinizing squamous cell carcinoma C. Small squamous cell carcinoma D. Adenocarcinoma E. Small cell carcinoma

38-year-old presented with a painless testicular mass, the mass was excised and stained for histopathology. The microscopical appearance confirms the diagnosis of a seminoma. Regarding this condition, which is true? A. It is the most common tumor in children aged 1-5yo B. The tumor frequently contains foci of coagulation necrosis with hemorrhage C. It is usually confined to the testis D. 95% of tumors stain positive for human chorionic gonadotropin (hCG) E. A neutrophilic infiltrate is usually present

25. A 49-year-old woman taking aspirin for increasing joint pain in her hands presents with increasing pain in her mid sternal area. Gastroscopy reveals multiple, scattered, punctate hemorrhagie areas in her gastric mucosa. Biopsies were taken reveal mucosal erosions with edema and hemorrhage. No mucosal ulceration is seen. Which of the following is the most likely diagnosis? A. Active chronic gastritis B. Acute gastritis C. Autoimmune gastritis D. Chronic gastritis

Bleeding from the nipple in a 45-year-old woman, without a palpable breast mass should suggest: A. fibroadenoma B. sclerosing adenosis C. intraductal papilioma D. chronic cystic mastitis

23. Massive splenomegaly is a characteristic clinical feature of all of the following diseases EXCEPT: A. Chronic myelogenous leukemia (CML) B. Myelofibrosis with myeloid metaplásia C. Gaucher disease D. Kala-azar. E. Infectious mononucleosis

For more than a decade, a 45-year-old male has had poorly controlled hypertension in the range of 160/95 mm Hg. For the past 3 months, his blood pressure has increased to 250/125 mm Hg. He now has a serum creatinine level of 3.8 mg/dL. Which of the following vascular lesions is most likely to be found in the kidneys? A. Hyperplastic arteriolosclerosis B. Granulomatous arteritis C. Fibromuscular dysplasia D. Polyarteritis nodosa

Which of the features of a spinal tap (cerebrospinal fluid examination) indicate viral infection? A. Predominance of lymphocyte B. Turbid appearance C. Markedly increased protein level D.Chronic myelogenous leukemia (CML) D. Decrease glucose level E. Predominance of polymorphonuclear cells