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Repost from Tips and Tricks of MRCOG
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Repost from RCOG guidelines summaries
Pre-Eclampsia and Maternal Cardiovascular
Function, SIP no. 79
🌟 Core message 🌟
Pre-eclampsia is not one disease. Viewed through the lens of the mother's circulation, it splits into two
haemodynamic phenotypes — a hypodynamic (resistance-dominant) pattern and a hyperdynamic (volume-dominant) pattern — which differ in timing, fetal consequences, maternal BMI, and, critically, in which antihypertensive and fluid strategy will help rather than harm.
Maternal cardiovascular dysfunction is detectable weeks before symptoms and in some women even before
conception, implying it is aetiological rather than merely consequential.
Non-invasive tools to measure
this exist and are safe in pregnancy, but remain largely confined to research settings.
The paper argues for moving them into routine care.
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