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| 6 | 622.explanation
Correct answer -A
NF-1 is diagnosed when any two of the following seven signs
are present:
1. Six or more café au-lait macules. Café au-lait spots are the hallmark of neurofibromatosis and are present in almost 100%
of patients.
2. Axillary or inguinal freckling consisting of multiple
hyperpigmented areas 2–3 mm in diameter.
3. Two or more iris Lisch nodules. Lisch nodules are hamartomas located within the iris and are best identified by a slit-lamp examination.
4. Two or more neurofibromas or one plexiform neurofibroma.
5. Osseous lesions such as sphenoid dysplasia (which may cause pulsating exophthalmos) or cortical thinning of long bones with or without pseudoarthrosis.
6. Optic gliomas are present in ≈15% of patients with NF-1.
7. First Degree relative with NF-1.
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| 8 |  622.Patient present with axillary frecking (as shown in image).
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