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🔻#3: PEP challenges amid rising STIs 🔸10-second takeaway Postexposure prophylaxis (PEP) with doxycycline is effective in preventing bacterial sexually transmitted infections (STIs) in cisgender men and transgender women at high risk, but there is limited data on its effectiveness in cisgender women. In this study, doxycycline PEP did not significantly reduce the incidence of new bacterial STIs in cisgender women at high risk compared to a screen-and-treat strategy, though adherence to the protocol may have been low. Further research is needed on effective patient-centered STI prevention methods for cisgender women at high risk. 🔹Access full text in the first comment👇

🔻#2: Post-PCI care: de-escalating DAPT in high-risk patients 🔸10-second takeaway In most patients, dual antiplatelet therapy (DAPT) de-escalation one month after percutaneous intervention (PCI) for an acute myocardial infarction (MI) is a safe and effective way to balance the risk of bleeding and subsequent ischemic events, but the safety of de-escalation in patients with high ischemic risk is unknown. In this study, DAPT de-escalation from ticagrelor (a potent P2Y12 inhibitor) to clopidogrel (a less potent P2Y12 inhibitor) 4 weeks after PCI was noninferior to continued ticagrelor-based DAPT in patients with high ischemic risk at one year after PCI. Long-term outcomes have not yet been reported. 🔹Access full text in the first comment👇

🔻#1: A new tool for PREVENTing CVD 🔸10-second takeaway The American Heart Association (AHA) has recently introduced Predicting Risk of CVD Events (PREVENT) equations in an effort to improve the ability to predict 10- and 30-year risks of cardiovascular disease (CVD) in adults aged 30–79 years. PREVENT addresses key gaps in the ACC/AHA pooled cohort equations (PCEs) with the inclusion of cardiovascular-kidney-metabolic (CKM) syndrome metrics and social determinants of health (if available). It also provides risk estimates for CVD subtypes, i.e., ASCVD and heart failure (HF). The development of an online calculator for clinical use is underway. 🔹Access full text in the first comment👇

💠One-Minute Telegram | #90, January 2024 The One-Minute Telegram is a journal club for busy doctors, with the latest research distilled down to just one minute. Are you ready to impress your attendings and colleagues? Read further for a detailed summary of these articles.✈️

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🔹iMD app - The biggest medical database library 🩺Clinical practice resources: ➖Uptodate 2023 ➖Epocrates 2023 ➖eTG Therapeutic Guidelines 2023 ➖Sanford guide 2023 💊Drug refrences: ➖Lexicomp 2023 ➖Micromedex 2023 ✅Qbanks: ➖UWORLD Qbanks 2023 ➖AMBOSS Qbanks 2023 ➖USMLE-Rx Qbanks 2023 ➖NBME Self assessments 2023 ➖CanadaQbank 2023 ➖AceQBank 2023 ➖BoardVitals Qbanks 2023 ➖BMJ OnExamination Qbanks 2023 ➖RADPrimer Lessons & Qbank 2023 ➖AMEDEX Qbank 2023 ➖MPlusX Qbank 2023 ➖PassMedicine Qbanks 2023 ➖PrometricMCQ Qbanks 2023 ➖TrueLearn Qbanks 2023 📺Video training & Lectures: ➖Oakstone CME ➖Mayo Clinic ➖123Sonography ➖MHMedical ➖Radiopaedia ➖Boards and Beyonds ➖DoctorsInTraining ➖Pixorize ➖Dr Najeeb ➖Kaplan ➖Lecturio ➖Osmosis ➖Accessmedicine Procedural Videos 📚More than 30 thousand Books & References from Elsevier, McGrawHill, Thieme, LWW, Oxford, ... 🔥GET all of these in ONE subscription 📱Available on Android, iOS & Mac 🔻contact us for more information: @Amboss_Team 🌐 Telegram Channel: @iMD_app_store

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💠Join our channels and groups:    💠Amboss    ⭐️@Amboss_Official    ✈️Amboss | One-Minute Telegram️:    ⭐️@Amboss_medical_news    ✔️Amboss | discount Offers️🌟:    ⭐️@Amboss_Offers    💻💻Amboss | USMLE step1 study group:    ⭐️@Amboss_Study    💻💻Amboss | USMLE step 2 CK | 3 study group:    ⭐️@Amboss_Group   💻💻USMLE Study partners group:     ⭐️@usmle_study_partners   👨‍⚕️👩‍⚕️USA Clinical Rotations group:     ⭐️@USA_Clinical_Rotations 🔻For contact :      ⭐@Amboss_Team 🔹Best wishes .