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Sample👇👇 Hello everyone and welcome to our module on endometrial disorders. Endometrium this is the mucosal surface of the uterus it consists of glands which can secrete mucus and also stroma which is connect Estrogen causes an increase in the number of gland to number stroma cells so that the endometrio air grows in size Michael and this is driven by hormones estrogen stimulates growth of those glands and stroma and progesterone switches over from a growth phase to a secretary phase In most of your textbooks showing the hormone fluctuations during the menstrual cycle and what those hormones do to the endometriom Are becoming longer and deeper. The second half of the menstrual cycle and then when we progesterone levels fall as shown by the screen line declining here that's what leads to menstruation. Driven in this portion of the menstrual cycle that's left proliferation but secretary vacuums appear there are prominent spiral arterials and all these changes are designed to prepare the uterus for possible pregnancy Disrefers to animal quantity duration or schedule of mental bleeding. Basically, women with heavy or irregular periods are said to have abnormal uterine bleeding and sometimes abnormally are implementing a subdivided into heavy menstrual bleeding and interments for bleeding. Women with heavy men for bleeding have heavy or prolonged periods and women with intermentally. First cause of abnormal uterine bleeding is Presence of endometrio glands in the miami trim and I talk about this in the video and endometriosis Women can have abnormal uterine bleeding and a classic audio toy disorder that causes uterine bleeding is an an aviator cycle which I'll talk about in just a minute. Endometrio causes refers to local problems in the endometriom that lead to uterine bleeding. Basically, if you catch all Women have none of the other causes on this slide. They're often presumed to have some local cause in their endometriom that leads to abnormal uterine bleeding. There are iconic causes of uterine bleeding, things like interior and devices or drugs that disrupt the ovulatory cycle or inhibit coagulation and can therefore cause uterine bleeding and then finally NOS is not Otherwise specify disrefers to very rare causes of that normal uterine bleeding. For example, women can develop 80 mil formations and rare cases and that can lead to uterine bleeding. Is a temporary under construction that forms each menstrual cycle and it's job is to secrete progesterone. So, when there's no ovulation and no corporate formation, this means there will be no ludial phase of the ovary and no switch in the ovary from estrogen to progesterone secretion as a result, the endometrium will undergo excessive growth From estrogen stimulation and this growth is excessive because it is called unopposed meaning there's no progesterone to oppose the estrogen effect so the uterine lining just keeps growing and growing and it sheds her regularly in this leads to irregular bleeding There's an underdeveloped type of the pituitary ovarian axis and women will often have an an alvatory cycle and they will begin menstruating with an irregular pattern Audio Tory Cycles. In addition, you can also see Anne Aviatory Cycles from other disorders. These can occur in the setting of thyroid disease. They're also common in women who are obese, fatty tissue, can produce estrogen, and this can disrupt the hypothalamus between also lead to Anne Aviatory cycles and an aviator cycles for any reason We'll lead to dysfunctional uterine bleeding. Inflammatory cells filling up the endometrio layer Easy to introduce bacteria The infections in acute endometriosis tend to be polymicrobial. It's unlikely the boards will ask you to identify the cause of agent Rates greater than 90% and alternative examples back cam and I talk about all these antibiotics and the infectious disease section [...]

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