Clinical Qbank(2nd year Subjects)

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322) 6. Ans. (b) Antimalarial Ref: Goodman & Gillman’s 13th ed. P 974 • Pyronaridine is an antimalarial structurally related to amodiaquine. • This drug is potent against both P. falciparum and P. vivax and is very well tolerated. • It leads to fever resolution in 1–2 days and parasite clearance in 2–3 days. • It is tested in clinical trials as an adjunct with artemisinin class drugs, has not yet been licensed. 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

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321) Ans. (c) Small cell lung CA • Azzopardi effect is basophilic staining of vascular walls due to encrustation by DNA from necrotic tumor cells. • It is seen in small cell lung carcinoma. 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

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320 ) Ans. (c) Collagen type 1 & 3 • In cirrhosis, types I and III collagen and other ECM components are deposited in the space of Disse. In advanced fibrosis and cirrhosis, fibrous bands separate nodules of hepatocytes throughout the liver. • In the normal liver, extracellular matrix (ECM) consisting of interstitial collagens (fibril-forming collagens types I, III, V, and XI) is present only in the liver capsule, in portal tracts, and around central veins. The liver has no true basement membrane; instead, a delicate framework containing type IV collagen and other proteins lies in the space between sinusoidal endothelial cells and hepatocytes (the space of Disse). 🎲For  more questions join @secondyearmbbsquestions and attend Live Quizzes @PrepNEXT at 9:30P.M Daily!!

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