AIMD Research

The Advanced MRI Section (AMRI) in the Intramural Research Program of the National Institute of Neurological Disorders and Stroke at the National Institutes of Health (NIH) in Bethesda, Maryland is seeking a postdoctoral fellow for the development of high resolution MRI methods to study iron and myelin distributions in the brain. Candidates interested in other projects in the Section will also be considered. Recent hardware and pulse sequence developments in AMRI have improved resolution robustness to head motion, and sensitivity to the unique effects of iron and myelin on image contrast. Novel methods are being developed to combine various MRI contrasts to improve the separation between iron and myelin. In part, this is based on detailed analysis of T2* and T2 signal decays in the various brain tissue types. AMRI maintains active collaborations with other research groups that have interest in applying novel methods to the study of neurodegenerative disorders and epilepsy. Other research in the group concerns the combined use of EEG and fMRI to characterize the contribution of neuronal and autonomic activity changes across the full range of arousal states during overnight sleep. As part of the NIH intramural program, AMRI has access to unique imaging and computational resources, including access to four 3 T and three 7 T MRI scanners, EEG and MEG systems, and a large (currently 107,000-core) computational cluster. A human 11.7 T is slated to be (re)energized early 2022. In addition, AMRI has expertise in state-of-the-art MR imaging techniques and data analysis tools, and a dedicated group of researchers including MRI physicists and sleep neuroscientists. The start date is flexible. Applicants are requested to send their curriculum vitae to Jeff Duyn, PhD (jeff.duyn@nih.gov). The applicant is encouraged to include contact information for three references from mentors and/or colleagues.

We are recruiting three Physician Scientists and/or Postdoctoral Fellows to participate in “National Career Development Consortium for Excellence in Glycosciences” training at the Johns Hopkins University School of Medicine or Cleveland Clinic (https://glycocareers.cclinic.jhu.edu/). The objective of this nationwide program is to invest in the career development of the next generation of “glycoscience literate” biomedical investigators. This fellowship will provide scholars with an unparalleled opportunity to participate in cross-disciplinary research, obtain advanced knowledge, skills, and professional exposure within the glycosciencs, as well as to develop a research portfolio from which to launch independent careers. Scholars (M.D., M.D.-Ph.D., or Ph.D.) will be funded for two years to work on projects that focus on studying the roles of glycans in the pathophysiology of diseases relevant to the mission of the National Heart Lung and Blood Institute. The professional development of scholars and cross-disciplinary training is supported by a co-mentorship structure. Projects will be broadly related to: Firstly) the role of O-GlcNAc in injury and in the pathophysiology of disease; Secondly) Immune regulation in airway diseases; Thirdly) Scholars already at Johns Hopkins can propose their own “Glyco-related project”. Potential scholars should contact Natasha Zachara (nzachara@jhmi.edu) or Ronald Schnaar (Schnaar@jhu.edu) to explore potential projects and co-mentors. Application process: Once projects are formulated scholars will submit an NIH style biosketch and statement of interest in PDF format to the admissions committee (GlycoED@jhmi.edu) no later than February 1st. The statement of interest should include a brief overview of the proposed project (based on discussion with Drs. Zachara and/or Schnaar), as well as a summary of the scholar’s long term career objectives (Arial 11 point, ½ inch margins, no less than single spacing). Additionally, scholars should have two letters of recommendation forwarded to the same email address. Benefits: Salary support appropriate with position of up to $100,000 per year (inclusive of benefits), research supplies ($25,000), and travel/training will be provided. Rigorous training in the Glycosciences (didactic and technical) will be provided, as well as opportunities for professional development

#Radiology Research Fellowship The ideal candidate for this position is someone with strong research interest in the field of cardiovascular or thoracic advanced imaging modalities. The candidate will work with UC Davis Cardiothoracic and Nuclear Medicine faculty in a variety of projects using advanced imaging techniques such as the Aquilon Precision CT Scanner, EXPLORER PET/CT and novel MRI pulse sequences. https://health.ucdavis.edu/radiology/education/research-fellowship.html

A Postdoctoral Research Fellow position is available at the Division of Neurosurgery, Beth Israel Deaconess Medical Center, Harvard Medical School for motivated M.D. applicants. J1 visa is supported for international applicants. Start date: July 2022 Requirements: - Strong publication record - English language proficiency - Proof of funding from home country In order to apply, please send the below documents to me at mkhorasa@bidmc.harvard.edu : - Updated CV - Cover letter (SOP) - At least one recommendation letter Please do not send an email unless it contains all above documents. Write "research fellowship" as the subject of the email. Please do not email me with queries about the position. If you have questions, you can message me on Linkedin or Instagram (@mirhojjat_k). P.S. re: the possibility of funding, it would depend on your own effort and ability to attract funding through grant applications. For instance I have been able to secure 92,000$ of funding in one year in the same position.

Department of Radiology, University of Washington in Seattle is hiring a post-doctoral research fellow with interest in musculoskeletal imaging and intervention. Candidate should be: 1. Interested in developing a career in academic radiology 2. MD and/or PhD with background in medical and imaging research 3. Proficient at research methodology and statistical analysis 4. Familiarity with coding, Phyton, and TensorFlow Position is funded for the 1st year. 2-yr commitment is required. 2nd year fund will be provided if available. This position does qualify for support of a J1 visa. Please send CV and brief Statement of Purpose to mchalian@uw.edu

POSTDOCTORAL POSITION Department of Otolaryngology/ F.M. Kirby Neurobiology Center Boston Children’s hospital and Harvard Medical School   Qualifications: Strong background and experience in electrophysiology. Responsibilities: The fellow will lead a program to study hair cell physiology in different mouse models with alterations in genes encoding for the mechanotransduction complex.   Funding is available immediately for a postdoctoral research position in the laboratory of Gwenaëlle Géléoc, PhD, Assistant Professor at Children’s Hospital Boston and Harvard Medical School.   Ongoing work involves the development and use of several mouse models, viral vectors,                                                                                                                                                                     hair cell physiological recordings, whole animal physiological analyses and imaging. The current position is open for applicants with a Ph.D. in Neuroscience or a related discipline and expertise in single cell electrophysiology. Experience in the auditory field is favored but not required.   The lab situated within the F.M. Kirby Neurobiology Center Children’s Hospital in the new Center for Life Sciences Building, 3rd floor, 3 Blackfan Circle, Boston, MA, adjacent to Children’s Hospital Boston and Harvard Medical School. Website: https://www.holtgeleoclab.com/   Applicants should send a CV, a statement of research interests and the names and contact information for three references to Dr. Gwenaelle Geleoc: Gwenaelle.Geleoc@childrens.harvard.edu

The Rahimi laboratory in the Center for Immunology and Inflammatory Diseases at Massachusetts General Hospital and Harvard Medical School is seeking a post-doctoral fellow to study Th2 cell fate decisions in the context of allergic immunity. We are interested in understanding the rules governing the development of long-lived memory Th2 cells that drive chronic allergic disease.   Current projects in the lab focus on (1) defining the crosstalk between lung dendritic cells and effector Th2 cells that regulate the development of tissue-resident memory Th2 cells and (2) defining the role of lipid metabolism in regulating Th2 cell fate.   We seek a highly motivated post-doctoral fellow (PhD, MD/PhD, or MD) with a background in immunology to lead our ongoing project defining the crosstalk between lung dendritic cells and effector Th2 cells during allergic immunity. International candidates are encouraged to apply. Experience working with mice, flow cytometry and/or advanced microscopy is required.   The Rahimi laboratory is funded through the NIH/NHLBI and institutional awards. This is a fully-funded position and project that provides an excellent opportunity to work in an exciting area within a dynamic, collaborative, and supportive group. Interested applicants should email their CV, a description of research accomplishments, and the names and email addresses of three references to: rrahimi@mgh.harvard.edu.

Postdoctoral Fellowship in Neural Engineering Section, Behavioral Neuroscience Research Branch The Intramural Research Program (IRP), National Institute on Drug Abuse (NIDA), a research component of the National Institutes of Health (NIH), Department of Health and Human Services (DHHS) has a junior postdoctoral position available starting after October 1, 2021 to conduct research aimed to understand neural mechanisms of substance abuse, using in vivo miniature fluorescence microscope calcium imaging in freely behaving rats The applicant will be part of a multidisciplinary neural engineering group focused on the development and application of miniScope imaging technology to study neuronal circuit function and dysfunction in motivated behavior and drug abuse Highly motivated and independent candidates with a solid publication record are strongly encouraged to apply Experience with behavioral neuroscience training and/or in vivo recordings, as well as basic Matlab/Python programing, is preferred This opportunity is located in Baltimore, MD The annual stipend is based on standard NIH postdoc salary scale Interested candidates must submit a CV, statement of research interests, and list of three reference via email to: Da-Ting Lin, Ph.D NIH NIDA IRP 333 Cassell Drive, Room 2206 Baltimore, MD 21224 Email: da-ting.lin@nih.gov

The Kleinstiver Laboratory (www.kleinstiverlab.org) in the Center for Genomic Medicine at the Massachusetts General Hospital, Harvard Medical School, is seeking highly motivated post-doctoral fellow candidates. We are recruiting a post-doctoral fellow to work collaboratively between our group and the Eichler Laboratory (https://eichler.mgh.harvard.edu/), on various projects seeking to bridge the optimization of CRISPR genome editing technologies and the development of translational editing approaches. The Kleinstiver Laboratory develops and applies CRISPR genome editing technologies for biomedical research and the treatment of human diseases. We utilize protein engineering methods to impart desirable properties into CRISPR nucleases, base editors, and prime editors, and seek to translate novel and optimized reagents molecular medicines. The candidate will play an integral role in projects related to genome editing technology development and applications in patient-derived tissues. The new hire will be appointed as a Research Fellow at the Massachusetts General Hospital and Post-Doc at the Harvard Medical School. Interested applicants should contact Dr. Ben Kleinstiver (bkleinstiver@mgh.harvard.edu) directly with their CV, a summary of their research accomplishments, and a brief description of research interests and career goals.

The Department of Anesthesiology at Columbia University Irving Medical Center, Vagelos College of Physicians and Surgeons, seeks a Postdoctoral Research Scientist in the lab of George Hasko, MD, PhD. The lab is focused on the regulation of immunity by purinergic receptors including ATP and adenosine receptors. The experiments conducted will use cellular and in vivo models of inflammation. An ideal applicant must have solid experience with contemporary techniques and experience with cellular and molecular techniques, including studies in cultured cells and in the isolation of primary cells from the mouse tissues such as liver, spleen, and macrophages. Additionally, the candidate should have expertise in working with mice, preparation of mRNA and protein lysates from tissues and cells, performance of real-time PCR and Western blotting and gene silencing approaches in cultured cells. Experience in RNA sequencing, ATAC sequencing and in CRISPR-Cas9 studies would be ideal. The selectee will also assist with the instructing and training of students, fellows, technicians and laboratory assistants as required. In addition, the selectee will submit purchase recommendations of equipment and supplies to his/her supervisor. Additional duties may be assigned as required. Qualified applicants must be a recent recipient of a PhD and/or MD awarded within the past three years. The only exception to this requirement is individuals of greater experience who wish to retrain themselves in a new discipline or specialty. The university offers a competitive salary and an excellent benefits package. This position falls under a collective bargaining agreement. Applicants can reach out to the Principal Investigator directly for more information regarding this position: George Hasko, MD, PhD, email: gh2503@cumc.columbia.edu

We are seeking multiple postdoctoral trainees to take on leading roles as part of the newly established Viral Epidemiology and Immunity Unit (VEIU). The VEIU is part of the Laboratory of Infectious Diseases (LID) within the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH). In the VEIU, we use a multidisciplinary approach to investigate immunological protec-tion against and susceptibility to emerging and reemerging viral diseases with the goal of informing how vaccines can be effectively and safely licensed and introduced through vaccination programs. Our research focuses on immunologically complex viral diseases with high global burden, including flaviviral diseases (such as dengue and Zika) and diseases caused by coronaviruses (including COVID-19). We will use a range of immunological assays and statistical tools to study determinants of disease in large observational cohort studies and vaccine trials. Postdoctoral trainees joining the VEIU will help design and implement projects, interacting directly with collaborators in the U.S. and internationally, including with experts leading longitudinal cohort studies in Nicaragua, Sri Lanka, Thailand, Ecuador, and the Philippines. Researchers in the VEIU will also be in-volved in establishing new clinical and observational studies at NIH and abroad. Candidates holding an M.D. and/or Ph.D. who are interested in joining the VEIU and have experience in one or more of the following areas of research are strongly encouraged to apply: • • B cell immunology • • RNA virus virology • • Epidemiology, biostatistics, or bioinformatics Candidates should have no more than four years of postdoctoral experience in directly related fields of re-search. Researchers with a passion for discovering broadly neutralizing antibodies; elucidating mecha-nisms of viral evolution and evolutionary dynamics; and leveraging large observational studies to address fundamental immunological questions would make outstanding additions to our team. To apply, interested candidates should please email a curriculum vitae (CV), a brief statement of research interests and experience (~1 page), a publication or manuscript the candidate has written, and the names and contact information for at least two references to Dr. Leah Katzelnick ( leah.katzelnick@nih.gov ). The position is fully funded, available immediately, and may be held for up to 5 years.

NIH-funded postdoctoral position is available in Dr. Ferrone’s research group in the Department of Surgery at the Massachusetts General Hospital and Harvard Medical School. The research  project is particularly focused on developing antibody-based immunotherapeutic strategies for the treatment of solid tumors with special emphasis on strategies to counteract the escape mechanisms utilized by tumor cells. The fellow will have the opportunity to also engage in a project which characterizes the significance and molecular basis of HLA class I defects in solid tumors. This position provides outstanding opportunities for continued scientific development and for contributing to pioneering research with high translational impact. The scientific environment at Massachusetts General Hospital and surrounding institutions such as Harvard and Massachusetts Institute of Technology offers ample opportunity for productive collaborations. We expect the fellow to be highly motivated, independent and innovative. We will provide support and mentorship so that the fellow ultimately develops his/her own line of research.   Job requirements: The candidate will have a PhD and/or MD degree. Prior laboratory experience is required, ideally in techniques such as cell culture-based assays, flow cytometry, IHC, fluorescence microscopy, Western blot, PCR, ELISA, in vivo murine models and CRISPR-Cas9. Likewise, knowledge of basic immunology is preferable.   Application Package Applications should be sent to sferrone@mgh.harvard.edu with the subject line “Postdoc – Tumor immunology and immunotherapy” and addressed to Dr. Soldano Ferrone. We prefer that the application package, submitted as a single pdf document, contains: 1) a cover letter, 2) a full CV with a complete list of publications, 3) name and contacts details of 3 references, and 4) list of laboratory and other methods mastered.

The Lai lab (https://www.lai-lab.com/) is a research group in the Division of Pulmonary and Critical Care Medicine at the Massachusetts General Hospital. The group conducts translational research on the effect of different environmental exposures on the human microbiome and lung diseases. Work in the lab is twofold, and involves both microbiology work as well as the application of computational approaches for the analysis and interpretation of next-generation sequencing data, particularly amplicon and shotgun metagenomics sequencing and related approaches. This training position is fully funded through a NIH grant (R01 AI144119 The school microbiome and asthma morbidity in inner-city children) and will focus on the role of the classroom microbiome on severity of asthma symptoms and the nasal microbiome of children. There are additional opportunities to work on other projects in the laboratory, which include a One Health project in Uganda looking at the effect of animal exposure on the human microbiome and lung health, a project looking at the effect of the chemical exposome on the gut microbiome, and a project focused on the lung and gut microbiome in COVID-19. These projects are well-suited to generate high impact publications, presentations at conferences and prepare the post-doctoral research fellow for a long-term career in academia or industry. Many of these projects have data already generated and are ready for the candidate to take the lead on analysis and manuscript preparation.      • Applicants must have substantial experience with genomics, epidemiologic or other statistical data analysis. Preference will be given to candidates with demonstrated research interests in relevant areas, particularly asthma, COPD, environmental health, and the human microbiome. Skills: • Excellent proficiency in R and unix is required. Additional proficiency in python is a plus. Proficiency with programming will be assessed with problem sets during the interview process. • Strong quantitative analysis skills and experience conducting statistical analyses with large datasets, particularly shotgun metagenomics data • Knowledge in at least one of the following areas:  environmental health, microbiology, lung biology, and mucosal immunology • Strong writing and verbal communication skills with the ability to critically interpret scientific data. At least one prior publication as lead author required. • Belief that teamwork is the key to success   Special Instructions: Please send curriculum vitae, names, contact information of three references, and a brief statement of goals to: plai@mgh.harvard.edu

Research Fellow - Dermatology and Aging Rochester Minnesota Responsibilities The Wyles Lab in the Robert and Arlene Kogod Center on Aging and Mayo Clinic Department of Dermatology has an immediate opening for a postdoctoral fellow interested in studying the association between cutting-edge biomarkers of skin aging and measure of wound healing.  In this role, the candidate will lead independent projects on studying the molecular and cellular mechanisms of skin senescence in humans and animal models.  https://apply.mayoclinic.org/TGnewUI/Search/Home/Home?partnerid=25309&siteid=5611#jobDetails=2852941_5611

A Postdoctoral Fellow position is available in the laboratory of Dr. Michael Mannstadt in the Endocrine Unit at the Massachusetts General Hospital (MGH). MGH is a Harvard Medical School (HMS)-affiliated hospital. This is a full-time position with an affiliated Research Fellow appointment proposed at Harvard Medical School (HMS). Employment is contingent upon successful completion of professional credentialing by the MGH Registrar/Credentialing Unit and final appointment by the Trustees of the Hospital to the Staff. PRINCIPAL DUTIES AND RESPONSIBILITIES: The Mannstadt laboratory investigates molecular mechanisms controlling the development and function of parathyroid glands, which produce parathyroid hormone that regulates calcium and phosphate homeostasis. We employ wide-ranging techniques to study parathyroid in vitro and in vivo. A major focus of the laboratory is to understand the differentiation of pluripotent stem cells towards parathyroid cells. These studies will lead to an improved understanding of parathyroid function and have important implications for treating parathyroid diseases. Qualifications : EDUCATION AND EXPERIENCE REQUIRED: • The ideal candidate will have a PhD, MD, or MD/PhD in the biomedical sciences, with experience in molecular/cell biology, biochemistry, and animal model systems. • Experience in cell culture, including stem cells, molecular/cell biology, and mouse models of disease, is preferred. • Qualified candidates should be able to work independently as well as in a group environment. WORKING CONDITIONS: • Duties will be performed in a research laboratory. No direct patient contact will occur. • Must be willing to work with mice. • Flexible work hours over a forty-hour workweek. APPLICATION REQUIREMENTS: Interested candidates should email a Cover Letter, CV, and references contact information to Dr. Michael Mannstadt c/o Olga Katsovskiy at okatsovskiy@mgh.harvard.edu

🔰One of the most frequent questions asked: ⁉️What if I found a person who has a research position, but they can't sponsor for my J-1 Visa? ✅ECFMG sponsors J-1 exchange visitors in the research scholar category for up to five years. More information: 🌐 https://www.ecfmg.org/evsp/applying-types-research-scholar.html and also: 🌐 https://j1visa.state.gov/programs/research-scholar

Postdoc position at #LungCancer research lab Our lab uses state-of-the art epigenomic approaches to examine gene regulatory programs that drive cellular diversity in lung cancer progression. To do this, we use varied lung cancer modeling approaches to study chromatin biology with the overarching goal of better understanding and targeting mechanisms of lung cancer progression. Contact: Lindsay LaFave, Ph.D. Albert Einstein College of Medicine Department of Cell Biology Chanin Building for Cancer Research Lindsay.lafave@einsteinmed.org Funded by NIH In Bronx, New York https://www.lafavelab.org/

Postdoctoral Positions at the NIH - Flavivirus and coronavirus B cell immunology, virology, and epidemiology We are seeking multiple postdoctoral trainees to take on leading roles as part of the newly established Viral Epidemiology and Immunity Unit (VEIU). The VEIU is part of the Laboratory of Infectious Diseases (LID) within the National Institute of Allergy and Infectious Diseases (NIAID) at the National Institutes of Health (NIH). In the VEIU, we use a multidisciplinary approach to investigate immunological protec-tion against and susceptibility to emerging and reemerging viral diseases with the goal of informing how vaccines can be effectively and safely licensed and introduced through vaccination programs. Our research focuses on immunologically complex viral diseases with high global burden, including flaviviral diseases (such as dengue and Zika) and diseases caused by coronaviruses (including COVID-19). We will use a range of immunological assays and statistical tools to study determinants of disease in large observational cohort studies and vaccine trials. Specifically, we are interested in: • antigenic and genetic viral evolution (https://science.sciencemag.org/content/349/6254/1338) • host immunological determinants of long-term protection and disease risk (https://science.sciencemag.org/content/358/6365/929, https://science.sciencemag.org/content/369/6507/1123) • dynamics of viral transmission in human populations (https://www.pnas.org/content/115/42/10762) Postdoctoral trainees joining the VEIU will help design and implement projects, interacting directly with collaborators in the U.S. and internationally, including with experts leading longitudinal cohort studies in Nicaragua, Sri Lanka, Thailand, Ecuador, and the Philippines. Researchers in the VEIU will also be in-volved in establishing new clinical and observational studies at NIH and abroad. Candidates holding an M.D. and/or Ph.D. who are interested in joining the VEIU and have experience in one or more of the following areas of research are strongly encouraged to apply: • • B cell immunology • • RNA virus virology • • Epidemiology, biostatistics, or bioinformatics Candidates should have no more than four years of postdoctoral experience in directly related fields of re-search. Researchers with a passion for discovering broadly neutralizing antibodies; elucidating mecha-nisms of viral evolution and evolutionary dynamics; and leveraging large observational studies to address fundamental immunological questions would make outstanding additions to our team. To apply, interested candidates should please email a curriculum vitae (CV), a brief statement of research interests and experience (~1 page), a publication or manuscript the candidate has written, and the names and contact information for at least two references to Dr. Leah Katzelnick ( leah.katzelnick@nih.gov ). The position is fully funded, available immediately, and may be held for up to 5 years.

A Postdoctoral Fellow position is available in the laboratory of Dr. Andrew Lane at the Johns Hopkins University School of Medicine, Department of Otolaryngology - Head and Neck Surgery. We use a combination of cutting-edge interdisciplinary approaches in immunology, molecular genetics, and immunohistochemistry to investigate the interaction between the immune system and epithelial cells in health and in chronic inflammatory disease. We are particularly interested in basic mechanisms underlying chronic rhinosinusitis with polyps, including subcellular pathways impacting progenitor cell physiology, innate immune defense, and epithelial repair. At this time, we are specifically focusing on how these pathways impact SARS-CoV-2 infection, in collaboration with virologist team members. We are seeking a highly motivated individual with a PhD or MD/PhD degree in immunology, stem cell biology, molecular biology, cell biology, or related fields to join our group in a collaborative environment promoting creative scientific research and career development. The successful candidate will have a strong work ethic, excellent organizational and communication skills, and critical thinking abilities. Salary is commensurate with experience. Interested individuals should submit a letter of interest; current curriculum vitae; and the names, addresses, and phone numbers of three references to: Andrew P. Lane, MD Professor, Otolaryngology - Head and Neck Surgery Director, Division of Rhinology, Allergy, and Skull Base Surgery alane3@jhmi.edu

A postdoctoral research fellow position is available in the Laboratory for Surgical and Metabolic Research at the Department of Surgery, Brigham and Women’s Hospital, Harvard Medical School. Research focus will include investigation of the mechanism of bariatric surgery, therapeutic targets to combat obesity related type 2 diabetes mellitus, and investigations of gastrointestinal metabolism and immunity. The successful candidate will work with a highly collaborative team of investigators and will be exposed to a wide array of state-of-the-art technologies, including cellular and molecular biology, metabolism, immunology, proteomics and innovative surgery animal models. There will be many opportunities to benefit from the rich and diverse scientific environment of Harvard Medical School.  Working Conditions: The laboratory environment is a BL2 (Biosafety Level 2) environment. Human tissue and animal tissue (bloodborne pathogens) are present at all times. Universal safety precautions must be adhered to and followed at all times. Laboratory also uses radioisotopes for some experimentation however exposure is of minimal risk. Chemical exposure is present at all times. Please send your CV, an outline of your research interests, and names and addresses of three references to Dr. Eric Sheu at esheu@bwh.harvard.edu