Oncology Updates

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Third-Line Therapy in Metastatic Colorectal Cancer https://www.nejm.org/doi/full/10.1056/NEJMc2306486?af=R&rss=currentIssue New England Journal of Medicine, Volume 389, Issue 2, Page 190-191, July 2023. ◾ @The_NEJM ◾

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Pirtobrutinib in Chronic Lymphocytic Leukemia https://www.nejm.org/doi/full/10.1056/NEJMoa2300696?query=featured_home In patients previously treated with covalent, irreversible BTK inhibitors, pirtobrutinib (a noncovalent, reversible BTK inhibitor) induced responses in 73%, with a median progression-free survival of nearly 20 months. ◾ @The_NEJM ◾

ASCO Highlight: Targeting Hidden Cancer https://www.medscape.com/s/viewarticle/993316?src=rss A pair of landmark studies presented at the meeting that show hidden cancer can be targeted with "really remarkable outcomes," says expert. MDedge News @MEDSCAPEnews

Defining and using immune archetypes to classify and treat cancer https://www.nature.com/articles/s41568-023-00578-2

Traject3d for studying 3D cellular heterogeneity https://www.nature.com/articles/s41568-023-00592-4

[Correspondence] HPV DNA and p16INK4a positivity in vulvar cancer and vulvar intraepithelial neoplasia https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00210-3/fulltext?rss=yes

[Correspondence] HPV DNA and p16INK4a positivity in vulvar cancer and vulvar intraepithelial neoplasia https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00174-2/fulltext?rss=yes

[Comment] Enhancing colon cancer care in restricted-resource settings https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00221-8/fulltext?rss=yes

[Correspondence] Artificial intelligence-based model for lymph node metastases detection in bladder cancer – Authors' reply https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00225-5/fulltext?rss=yes

[Correspondence] Radiotherapy for children and adolescents with early-stage classical Hodgkin lymphoma – Authors' reply https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00235-8/fulltext?rss=yes

[Correspondence] Artifical intelligence-based model for lymph node metastases detection in bladder cancer https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00152-3/fulltext?rss=yes

[Correspondence] Dose recommendations for anticancer drugs in patients with renal or hepatic impairment: an update https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00216-4/fulltext?rss=yes

[Correspondence] Radiotherapy for children and adolescents with early-stage classical Hodgkin lymphoma https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00211-5/fulltext?rss=yes

[Comment] Uterine cancer mortality and Black women: time to act https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00113-4/fulltext?rss=yes

[Comment] Cancer research funding data to drive collaboration and inform action https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00153-5/fulltext?rss=yes

[Policy Review] Setting International Standards in Analyzing Patient-Reported Outcomes and Quality of Life Endpoints in Cancer Clinical Trials-Innovative Medicines Initiative (SISAQOL-IMI): stakeholder views, objectives, and procedures https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00157-2/fulltext?rss=yes

[Articles] The prognosis of patients with small cell carcinoma of the cervix: a retrospective study of the SEER database and a Chinese multicentre registry https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00185-7/fulltext?rss=yes

[Correspondence] Artificial intelligence-based model for lymph node metastases detection in bladder cancer https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(23)00209-7/fulltext?rss=yes