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Channel Posts
35-year-old man presents with a 2-year history of an abnormal nail growth involving a single digit associated with intermitte
35-year-old man presents with a 2-year history of an abnormal nail growth involving a single digit associated with intermittent tenderness. He reports gradual enlargement of the lesion over time. Hedenies preceding trauma, bleeding, drainage, or pigmentary change. No prior treatments have been attempted. He otherwise feels well without additional skin or nail concerns. On physical examination, there is a localized dystrophic nail plate abnormality involving a single digit with associated longitudinal erythronychia and subungual hyperkeratotic growth (Figures 1 and 2). Mild tenderness is elicited with palpation. No surrounding erythema, drainage, or ulceration is appreciated. The remainder of the skin and nail examination is unremarkable. What is the most likely diagnosis? A- Glomus tumor B-Onychomatricoa C-Onychopapilloa D- Subungual verruca vulgaris

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Which type of ultraviolet radiation is the most potent contributor to the clinical reaction shown? A. UVA B. UVB C. UVC from natural sunlight D. Infrared radiation E. Visible light
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An adult woman presents with painful, erythematous areas of skin after excessive exposure to sunlight. The affected areas are
An adult woman presents with painful, erythematous areas of skin after excessive exposure to sunlight. The affected areas are warm and tender. The clinical appearance is shown in the photographs above . What is the most likely diagnosis? A. Polymorphic light eruption B. Solar urticaria C. Sunburn D. Cutaneous lupus erythematosus E. Dermatomyositis.
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A 17-month-old boy presents with a 1-year history of multiple asymptomatic yellow-orange papules and nodules on the head, fac+2
A 17-month-old boy presents with a 1-year history of multiple asymptomatic yellow-orange papules and nodules on the head, face, neck, and upper back. Laboratory investigations and systemic evaluation are normal. Skin biopsy demonstrates foamy histiocytes and numerous Touton giant cells. Immunohistochemistry shows CD68 positive, S-100 negative, and Langerin negative. What is the most likely diagnosis? A. Langerhans cell histiocytosis B. Mastocytoma C. Eruptive xanthoma D. Juvenile xanthogranuloma (JXG) E. Benign cephalic histiocytosis
377
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A 45-year-old man presents with a 1-year history of progressively dry, rough skin involving the bilateral lower extremities.
A 45-year-old man presents with a 1-year history of progressively dry, rough skin involving the bilateral lower extremities. He reports associated mild pruritus that worsens during colder weather and after prolonged hot showers. The rash has not significantly improved despite regular use of over-the-counter emollients and moisturizers. He denies pain, blistering, drainage, or systemic symptoms. His medical history is otherwise unremarkable, and he denies a personal or family history of psoriasis, eczema, or autoimmune disease. On examination, there are fine polygonal brown-to-gray adherent scales over the bilateral shins with background xerosis . The flexural surfaces are relatively spared. There is no erythema, fissuring, or no skin secondary infection. What is the most likely diagnosis? A- Asteatotic eczema B- Stasis dermatitis C- Ichthyosis vulgaris D- Terra firma-forme dermatosis
440
6
62-year-old man presents for evaluation of a persistent “rash” on his trunk that has been present for several months. He repo
62-year-old man presents for evaluation of a persistent “rash” on his trunk that has been present for several months. He reports the gradual development of brown discoloration that has not improved despite regular washing with soap and water. The lesions are asymptomatic, without associated itching, pain, or bleeding. He denies any recent changes in personal hygiene products or medications and denies systemic symptoms. His medical history is unremarkable. On examination, there are yellow-brown, thin, rough plaques with a “dirty” appearance on the chest and back. The lesions are non-tender and lack surrounding erythema, scale, or signs of inflammation. No excoriations, vesicles, or purpura are noted. Gentle swabbing of the affected areas with isopropyl alcohol pads results in immediate removal of the plaques, revealing normal underlying skin. What is the most likely diagnosis? A- Confluent and reticulated papillomatosis (CARP) B- Dermatosis neglecta C- Pityriasis versicolor D- Terra firma-forme dermatosis
545
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Add She has no history of autoimmune disease, vascular disorders, or prior similar conditions and is not taking any medications.
634
8
20-year-old woman presents with episodic color changes of her fingertips triggered by cold exposure, including holding cold b
20-year-old woman presents with episodic color changes of her fingertips triggered by cold exposure, including holding cold beverages. She reports that the episodes begin with pallor and a numb sensation, followed by a dusky or bluish discoloration, and then bright red discoloration upon rewarming of her fingers. These episodes are intermittent and have been occurring for several years. She notes mild discomfort during attacks but denies ulceration, persistent pain, or tissue breakdown. On physical examination during an episode, there is sharply demarcated pallor of multiple fingertips . The involved digits are cool to the touch, and the findings are present in both hands. No ulceration or digital pitting is observed. There is no evidence of skin thickening, sclerodactyly, or telangiectasias. Nailfold capillary examination is unremarkable, without dilated or tortuous capillaries. What is the most likely diagnosis? A- Scleroderma B- Primary Raynaud phenomenon C- Arsenic poisoning D- Hypothenar hammer syndrome
628
9
A 54-year-old man presents for a wellness examination and discloses that he has had chronic, painful open wounds on his hands
A 54-year-old man presents for a wellness examination and discloses that he has had chronic, painful open wounds on his hands, forearms, and face. The wounds start as painful blisters that eventually drain and crust. Despite 2 months of basic wound care, he returned with severe, dramatic worsening of the crusting on his face and scalp, as well as ulceration and necrosis of the unhealed wounds on his hands and forearms .The patient is unhoused and spends a great deal of time in the sun. His medical history is pertinent for tobacco use, alcoholism, and untreated hepatitis C. Blood was drawn and sent to the lab, confirming untreated hepatitis C and the presence of serum porphyrins. What is the most likely diagnosis? A- Bullous pemphigoid B- Porphyria cutanea tarda C- Bullous impetigo D- Pemphigus vulgaris
700
10
A 24-year-old woman presents with a 1-week history of a new facial rash around the mouth. She reports a gradual onset of smal
A 24-year-old woman presents with a 1-week history of a new facial rash around the mouth. She reports a gradual onset of small red bumps accompanied by mild burning and occasional pruritus. No pain, drainage, or systemic symptoms. She is employed in a health care setting and notes frequent mask use at work. She also reports regular use of facial moisturizers, but no recent changes in skincare products. No use of topical corticosteroids, inhaled steroids, or new oral medications. Her past medical history negative .On physical examination, numerous small erythematous papules and a few pustules are distributed around the perioral region, involving the nasolabial folds and chin . The vermilion border is notably spared, creating a zone of uninvolved skin immediately adjacent to the lips. No vesicles, crusting, or signs of secondary infection are observed. The remaining face is spared. What is the most likely diagnosis? A- Contact dermatitis B- Seborrheic dermatitis C- Rosacea D- Periorificial dermatitis
719
11
middle-aged man presents with a growth on his right ear that has been present for over a year. The patient reports that the l
middle-aged man presents with a growth on his right ear that has been present for over a year. The patient reports that the lesion has been growing slowly and occasionally bleeds. Physical examination reveals a group of erythematous papules in the triangular fossa of the right ear . A shave biopsy of the ear lesion was performed. Histologic examination of the biopsy specimen reveals a polypoid vascular lesion with lymphocytes and numerous eosinophils . The endothelial cells appeared swollen and focally showed fenestration . Further immunohistochemistry studies were conducted. ERG and CD34 stains highlight the endothelial cells , while the HHV-8 stain was negative. What is the most likely diagnosis? A- Eosinophilic granuloma B- Pyogenic granuloma C- Basal cell carcinoma D- Angiolymphoid hyperplasia with eosinophilia
749
12
28-year-old woman presents with recurrent, painless patches on her tongue. She notes that the patches have flared intermitten
28-year-old woman presents with recurrent, painless patches on her tongue. She notes that the patches have flared intermittently over years. The patches seem to change in size, shape, and location over several days, sometimes migrating to different parts of the tongue. She denies bleeding or ulceration, but reports occasional mild sensitivity with spicy or acidic foods during flares. She has no significant past medical history and is not taking any medications. She does not use tobacco and has no known dermatologic history aside from mild atopy.  On physical examination, there are multiple, well-demarcated, erythematous, smooth patches on the dorsal tongue with serpiginous, slightly raised white borders (Figure). The lesions vary in size and distribution. The surrounding mucosa is normal, without induration, ulceration, or evidence of secondary infection.What is the most likely diagnosis? A- Candidiasis B- Erythroplakia C- Lichen planus D- Migratory glossitis
761
13
A 42-year-old woman presents to the dermatology clinic for evaluation of progressive skin discoloration. She reports graduall
A 42-year-old woman presents to the dermatology clinic for evaluation of progressive skin discoloration. She reports gradually developing light patches on her hands and around her mouth over the past year. The areas are asymptomatic, though she notes occasional mild pruritus. She denies a preceding rash, trauma, or new topical exposures. Her history is notable for autoimmune thyroid disease. Physical examination reveals multiple well-demarcated depigmented macules and patches on the dorsal hands and perioral region. Some areas demonstrate leukotrichia within the patches. There is no scale, erythema, or induration. QUESTION What is the most likely diagnosis? A- Nevus depigmentosus B- Vitiligo C- Tinea (pityriasis) versicolor D- Progressive macular hypomelanosis
750
14
76-year-old man presents to the dermatology clinic for evaluation of 2 firm lesions on his left ear. He reports first noticin
76-year-old man presents to the dermatology clinic for evaluation of 2 firm lesions on his left ear. He reports first noticing them several months ago, with no change in size. The lesions are asymptomatic and without pain, pruritus, bleeding, or prior trauma. The patient has a history of significant sun exposure. His past medical history is unremarkable. Physical examination reveals well-circumscribed, firm, subcutaneous nodules on the helix of the left ear, each measuring a few millimeters in diameter. The overlying skin is intact without erythema, scale, or ulceration, and the lesions are non-tender. The remainder of the skin examination is un remarkable.What is the most likely diagnosis? A- Keloid B- Basal cell carcinoma C- Weathering nodule D- Seborrheic keratosis
749
15
45-year-old Black man presents for evaluation of residual skin changes on the right side of his torso. He reports that approx
45-year-old Black man presents for evaluation of residual skin changes on the right side of his torso. He reports that approximately 2 months ago, he developed a sudden-onset, intensely pruritic rash in this area that gradually spread across the right lateral chest and abdomen. The eruption has since improved without treatment, but he notes persistent dark marks where the rash had been. He denies pain, fever, recent illness, new medications, or new topical exposures. His past medical history is unremarkable. Physical examination reveals multiple hyperpigmented macules and patches arranged in 2 separate linear bands along the right lateral chest and abdomen. The bands follow a curvilinear pattern, remain confined to the right side without crossing the midline, and are separated by a strip of normal-appearing skin. The remainder of the skin examination is unremarkable. What is the most likely diagnosis? A-Purpura B- Lichen planus C- Blaschkitis D- Eczema
770
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A 73-year-old White man presents for evaluation of gradually progressive facial skin changes. He reports that over the past s
A 73-year-old White man presents for evaluation of gradually progressive facial skin changes. He reports that over the past several years, he has noticed an increasing number of “blackheads” and small bumps around his eyes and upper cheeks. The lesions do not cause pain, pruritus, or drainage. His past medical history is notable for hypertension, and he reports a 40-pack-year smoking history. He worked as a farmer for over 40 years and rarely used sun protection. Physical examination reveals numerous open comedones and cystic papules clustered symmetrically over the periorbital and zygomatic regions bilaterally. The surrounding skin appears thickened, yellowish in hue, and with prominent wrinkling. The lesions are non-tender and without surrounding erythema or inflammation. No similar findings are noted on the chest or back. The remainder of the skin examination is unremarkable. What is the most likely diagnosis? A-Milia B- Acne C- Favre-Racouchot D- Colloid milia
752
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A 35-year-old man presents to the dermatology clinic for evaluation of a skin lesion on his right calf. He reports noticing t
A 35-year-old man presents to the dermatology clinic for evaluation of a skin lesion on his right calf. He reports noticing the bright red spot approximately 8 months ago and has remained the same size. He also noted a few similar spots on his trunk. All of the lesions are entirely asymptomatic and have never bled. His medical history is unremarkable, and he takes no daily medications. On physical examination, the skin of the right calf reveals a well-demarcated, dome-shaped, bright red-colored papule. Examination of the trunk reveals a few similar 1 mm to 5 mm vascular proliferations. What is the most likely diagnosis? A- Lobular capillary B- hemangioma C- Pyogenic granuloma Cherry angioma Glomeruloid hemangioma
756
18
24-year-old woman presents for evaluation of a persistent, itchy rash on her right arm. She reports that over the past several months, she has noticed a dry, irritated patch in the crease of her right elbow. The lesion is associated with intense pruritus, which frequently leads to repeated scratching. She notes that the redness and itching are significantly exacerbated after taking long, hot showers. She denies any spontaneous hives, spreading of the rash, pain, or systemic symptoms. Her medical history is notable for childhood asthma and seasonal allergic rhinitis, but she is not currently taking any daily medications. Clinical evaluation of the right antecubital fossa reveals a poorly defined erythematous plaque with lichenification and scaling. Excoriations are present within the plaque, corresponding to the patient’s reported pruritus. No vesicles, weeping, or purpura are noted. The remainder of the skin examination is notable for generalized mild xerosis but otherwise unremarkable. What is the most likely diagnosis? A- Allergic contact dermatitis B- Atopic dermatitis C- Psoriasis vulgaris D- Tinea corporis
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No text...
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24-year-old woman presents for evaluation of a persistent, itchy rash on her right arm. She reports that over the past several months, she has noticed a dry, irritated patch in the crease of her right elbow. The lesion is associated with intense pruritus, which frequently leads to repeated scratching. She notes that the redness and itching are significantly exacerbated after taking long, hot showers. She denies any spontaneous hives, spreading of the rash, pain, or systemic symptoms. Her medical history is notable for childhood asthma and seasonal allergic rhinitis, but she is not currently taking any daily medications. Clinical evaluation of the right antecubital fossa reveals a poorly defined erythematous plaque with lichenification and scaling. Excoriations are present within the plaque, corresponding to the patient’s reported pruritus. No vesicles, weeping, or purpura are noted. The remainder of the skin examination is notable for generalized mild xerosis but otherwise unremarkable. What is the most likely diagnosis? A- Allergic contact dermatitis B- Atopic dermatitis C- Psoriasis vulgaris D- Tinea corporis
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