Dr.Najeeb notes & Medical notes
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A channel containing all videos lecture notes of Dr. Najeeb sir
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Channel Dr.Najeeb notes & Medical notes (@drnajeebvideonotesmbbsnotes) in the English language segment is an active participant. Currently, the community unites 13 238 subscribers, ranking 1 968 in the Medicine category.
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Since its creation on невідомо, the project has demonstrated rapid growth, gathering an audience of 13 238 subscribers.
According to the latest data from 21 December, 2025, the channel demonstrates stable activity. Although there has been a change in the number of participants by 360 over the last 30 days and by 0 over the last 24 hours, overall reach remains high.
- Verification status: Not verified
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- Post reach: On average, each post receives 0 views. Within the first day, a publication typically gains 0 views.
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- Thematic interests: Content is focused on key topics such as drug, morphine, patient, following, pathology.
📝 Description and content policy
The author describes the resource as a platform for expressing subjective opinions:
“A channel containing all videos lecture notes of Dr. Najeeb sir”
Thanks to the high frequency of updates (latest data received on 22 December, 2025), the channel maintains relevance and a high level of publication reach. Analytics show that the audience actively interacts with content, making it an important point of influence in the Medicine category.
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Posts Archive
A 23-year-old woman has prolonged episodes of wheezing, dyspnea, and anxiety that are relieved by ẞ- adrenergic agonists. The major mediator of her condition is
A) bradykinin
B) eosinophil chemotactic factors
D) prostaglandin E
C) leukotrienes
E) thromboxane
30 A 30-year-old man develops urinary incontinence 2 weeks after successful treatment of a fracture of the left pelvis that was sustained at work. He was pinned against a loading der fills to capacity dock by a truck moving in reverse. Physical examination shows a distended bladder Cystometrography shows absence of micturition reflexes. After the bladder overflow of urine occurs through the urethra a few drops at a time. This patient most likely sustained additional injury to which of the following during his initial accident? A
A) External urinary sphincter
B) Hypogastric nerve
C) Pelvic nerves
D) Pudendal nerves
E) Skeletal motor fibers
A 1-year-old girl is admitted to the hospital because of a fracture of the right femur and bone deformities She had bilateral clavicle fractures at birth. Oral examnation shows si erupted grity-to-translucent, pointed teeth X-rays of the long bones show generalized osteopenia Genetic studies show a substitution of an alanine for a glycine residalyp collagen. Which of the following has most likely occurred in this patient as a result of this mutation?
A) Decreased hydrogen-bond formation between collagen molecules
B) Decreased proline hydroxylation
C) Disruption of the secondary structure of collagen molecules D) Increased rate of collagen degradation
E) Weakened interaction between collagen and proteoglycan
6 A 48-year-old woman comes to the physician because of a a 3-month history of fatigue, weakness, loss s of appelite, and weight loss. Her serum parathyroid hormone concentrations are increased X-rays of the skeletal system show generalized osteopenia, with subperiosteal resorption of bone within the phalanges. Which of the following mechanisms is the most likely cause of the skeletal changes observed in this patient?
A) Impaired calcification of preformed osteoid
B) Paracrine stimulation of osteoclasts by osteoblasts C) Parathyroid hormone-mediated induction of calcitonin
D) Parathyroid hormone-mediated induction of interleukin-1 (IL-1)
E) Parathyroid hormone-mediated production of transforming growth factor-B,
An investigator is studying the efficacy of distinct vaccine formulations directed against the capsular polysaccharides of Neisseria meningitidis. The carbohydrates are chemically conjugated to various compounds and injected into laboratory mice. Titers of anticapsular IgG antibodies are then measured. Which of the following compounds is most likely to induce increased titers of these antibodies when conjugated to the polysaccharides?
A) Dinitrophenol
B) Flagellin
C) Lactose
D) Lipopolysaccharide
E) Palmitic acid
F) Polyinosinic acid-polycytidylic acid
The gene that codes for a protein normally found in the endoplasmic reticulum is mutated, and the protein produced by the mutated gene remains in the cytoplasm. Which of the following mutations is most likely to impair the transport of the protein into the endoplasmic reticulum?
A) Conversion of a proline residue to a hydroxyproline residue
B) Deletion of a hydrophobic amino acid sequence from the N terminus
C) Disruption of a lysine-rich amino acid sequence near the middle of the protein
D) Loss of a glycosylation site
E) Premature termination of the polypeptide chain near the C terminus
48-year old man is referred for evaluation of possible hypertension. On the basis of ten measurements, the patient's average diastolic blood pressure is 113 mm Hg. and the standard deviation is 8 mm Hg. If four rather than ten measurements of the mean blood pressure are made, which of the following is the expected impact on the size of the 95% confidence interval about the mean blood pressure??
A) Change, but the direction cannot be predicted
B) Decrease in width
C) Increase in width
D) Remain the same
2. A 20-year-old man comes to the physician n for evaluation of infertility Physical Physical examination shows s no abnormalities. His serum concentrations of testosterone, follicle-stimulating hormone, luteinizing hormone, and prolactin are within the referenice ranges. Which of the following is most likely to be found in an abnormal concentration on sermen analysis?
A) Fructose
B) 5-Reductase
C) Selenium
D) Sodium
E) Zinc
Drugs A and B are 2 new experimental drugs being tested for the treatment of a novel respiratory viral infection that causes acute respiratory failure and death in children. Part of the testing process is to analyze the 2-week survival after treatment to determine the clinical efficacy of the experimental drugs. A total of 60 children recently diagnosed with the disease are randomly assigned in a 1:1:1 ratio to receive Drug A, Drug B, or placebo. The absolute risk reduction of Drug A compared to placebo was found to be 0.05, whereas the absolute risk reduction of Drug B compared to placebo was found to be 0.20. Based on these results, which of the following statements comparing the effectiveness of Drugs A and B in treating children infected with the novel virus is most appropriate?
A.Drugs A and B require treating the same number of children to prevent 1 additional death, so they are equally effective
B.Drug A requires treating fewer children to prevent 1 additional death compared to Drug B, so Drug A is less effective than Drug B
C.Drug A requires treating fewer children to prevent 1 additional death compared to Drug B, so Drug A is more effective than Drug B
D.Drug A requires treating more children to prevent 1 additional death compared to Drug B, so Drug A is less effective than Drug B
E.Drug A requires treating more children to prevent 1 additional death compared to Drug B, so Drug A is more effective than Drug B
Pharmacologic researchers develop a novel alkylating chemotherapeutic agent against glioblastoma multiforme. They find that malignant cells with methylation of the promoter region for the O-methylguanine-DNA methyltransferase (MGMT) gene are more susceptible to this drug than cells without methylation. Which of the following is the most likely function of the protein encoded by the gene?
A.Induction of apoptosis
B.Reducing major histocompatibility complex expression
C.Repairing DNA damage
D.Upregulation of telomerase
A 25-year-old woman, gravida 1, para 0, who is Rh-negative, delivers a full-term Rh-positive neonate. The mother is given prophylactic anti-Rho(D) immune globulin immediately post partum. During her second pregnancy 3 years later, she is screened each trimester for Rho(D) antibodies. An indirect antiglobulin test done during the third trimester indicates the presence of anti-Rho(D) antibodies in her serum. Which of the following is the most likely mechanism for the occurrence of these maternal antibodies?
A) Anamnestic production of maternal anti-Rho(D) immunoglobulin
B) Intrauterine transplacental fetal-maternal hemorrhages during the second pregnancy
C) Residual circulating prophylactic anti-Rho(D) immunoglobulin
D) Transplacental passage of fetal IgG anti-Rho(D) antibodies
Sudden withdrawal from which of the following substances is most likely to produce a life-threatening syndrome in a person dependent on
that substance?
A) Amphetamine
B) Cocaine
C) Heroin
D) Methylphenidate
E) Secobarbital
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Today: Blocks 1 & 2.
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I use the term 'My World' to refer to UWorld, which contains more then 3,740 MCQs with explanations in its latest version, randomly arranged.
