pharmacy knowledge youtube channel

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1. Which is cytotoxic from following marine? (bryostatin) 2. To avoid crystallization of syrup which substance is added? (polyhydric alcohols) 3. Particle size of fluid energy mill is? (1-30micrometer) 4. Use of Gallic acid? (Antioxidant) 5. HLB of o/w emulsion. (3-8) 6. Range of Visible light? (400-800nm options were in micro so read questions carefully before attaining ) 7. Source of IR (Nerst glower) 8. Hydrogen bonding determined by which method? (Raman) 9. Most intense peak in MASS spectra? (Base peak) 10. How to determine non-UV active structure? (derivatization) 11. Energy comparison of UV, IR n NMR. Means put them in ascending order of their energies. (NMR least

“J” List of diseases and ailments that drug should not claim to cure Ex. Cancer, AIDS, Cataract, Diabetes…etc “K” List of drugs that are exempted from certain provisions regarding manufacture “M” Requirements of manufacturing premises, GMP requirements of factory premises, plants and equipments “M1” Requirements of factory premises for manufacture of Homeopathic medicines “M2” Requirements of factory premises for manufacture of cosmetics “M3” Requirements of factory premises for manufacture of medical devices “N” List of equipment to run a Pharmacy “O” Standards for disinfectant fluids Ex… Phenol, H2O2, alcohol…. “J” List of diseases and ailments that drug should not claim to cure Ex. Cancer, AIDS, Cataract, Diabetes…etc “K” List of drugs that are exempted from certain provisions regarding manufacture “M” Requirements of manufacturing premises, GMP requirements of factory premises, plants and equipments “M1” Requirements of factory premises for manufacture of Homeopathic medicines “M2” Requirements of factory premises for manufacture of cosmetics “M3” Requirements of factory premises for manufacture of medical devices “N” List of equipment to run a Pharmacy “O” Standards for disinfectant fluids Ex… Phenol, H2O2, alcohol…. “P” Life period(expiry) of drugs Ex. Insuline Inj. – 24 months “Q” Coal tar colors permitted to be used in cosmetics Ex. Caramel, TiO2, Toney red….. “R” Standards for mechanical contraceptives “R1” Standards for medical devices “S” Standards for cosmetics “T” Requirements (GMP) of factory premises for Ayurvedic, Siddha, Unani drugs “U” Manufacturing and analytical records of drugs “U1” Manufacturing and analytical records of cosmetics “V” Standards for patent or proprietary medicines “W” List of drugs marketed under generic names- Omitted “X” List of narcotic drugs and psychotropic substances EX. Opium, Morphine, Barbital…… “Y” Requirement and guidelines on clinical trials for import and manufacture of new drugs.. pharmacy knowledge YouTube channel. Join us on other social media 👇🏻 YouTube  :- https://youtube.com/@pharmacyknowledge?si=F2cIcY5YjJhWjCgl Telegram :- https://t.me/pharmacyandknowledge Facebook Page :- https://www.facebook.com/pharmacygyan?mibextid=ZbWKwL Facebook Group :- https://m.facebook.com/groups/879743609167321/?ref=share&mibextid=NSMWBT Instagram :- https://www.instagram.com/pharmacyandknowledge?igsh=Z3VyMXh0c3loY3Q1 01. Immunoglobulin is? (2 light, 2 heavy, disulfide) 02. Which of following not causing enzyme induction? (Sulfonamide) 03. Detector used in IR? (Thermocouple) 04. Function of microvilli is? (Increase surface area) 05. pH of 0.005M HCL? 06. pH of pKa 5.4 is? 07. IR range of CO (acid chloride) 08. Neostigmin does not cross BBB? (Polar) 09. Drugs which cross BBB are? (lipophilic drugs) 10. Which is most commonly used HPLC? (Reverse Phase) 11. Phenolphthalein is? (Acid base indicator) 12. Drug assayed by acid-base back titration? (Aspirin) 13. Which of following is titrated using strong base? (Refer IP for titrations, this can be considered as important) 14. Amiloride and Spiranolactone differs in? 15. Statin mechanism? (Reduce cholesterol) 16. Which of following is not related with enalapril (It is not an AT1 antagonist) 17. Equation of Angle of Repose. 18. Character of liposome is? 19. Eye drops and parentral differ in? 20. Colchicines is used in Gout. __ Join us on other social media 👇🏻 YouTube :- https://youtube.com/@pharmacyknowledge?si=F2cIcY5YjJhWjCgl Telegram :- https://t.me/pharmacyandknowledge Facebook Page :- https://www.facebook.com/pharmacygyan?mibextid=ZbWKwL Facebook Group :- https://m.facebook.com/groups/879743609167321/?ref=share&mibextid=NSMWBT Instagram :- https://www.instagram.com/pharmacyandknowledge?igsh=Z3VyMXh0c3loY3Q1

7. Cheese reaction :- phentolamine 8. Atropine poisoning :- physostigmine 9. Cyanide poisoning :- amyl nitrite 10. Benzodiazepine poisoning:- flumazenil 11. Cholera :- tetracycline 12. KALA-AZAR :- lipozomal amphotericin- B 13. Iron poisoning :- desferrioxamine¬ ¬ 14. MRSA :- vancomycin 15. VRSA :- LINEZOLID 16. Warfarin overdose :- vitamin-K (NIPER- 2009) 17. OCD :- fluoxetine 18. Alcohol poisoning :- fomepizole 19. Epilepsy in pregnency :- phenobarbitone 20. Anaphylactic shock :- Adrenaline 21. MRSA Infection-Vancomycin 22. Malaria in Pregnancy-Chloroquine 23. Whooping Cough or Perteusis- Erythromycin 24. Kawasaki disease-IV Ig 25. Warfarin Overdose-Vit-K 26. Heparin Overdose-Protamine 27. Hairy Cell Leukemia-Cladirabine 28. Multiple Myeloma- Melphalan 29. CML-Imatinib 30. Wegner's granulomatosis-Cyclophosphamide 31. HOCM- Propranolol 32. Delirium Tremens-Diazepam 33. Drug Induced Parkinsonism-Benzhexol 34. Diacumarol Poisoning-Vit-K 35. Type-1 Lepra Reaction-Steroids 36. Type- 2 Lepra Reaction-Thalidomide 37. Allergic Contect Dermatitis-Steroids 38. PSVT- 1st-Adenosine, 2nd-Verapamil, 3rd-Digoxin 39. Z-E Syndrome- Proton Pump Inhibitor 40. Chancroid-Cotrimoxazole 41. Dermatitis Herpetiformis-Dapsone 42. Spastic Type of Cerebral Palsy-Diazepam 43. Herpes Simplex Keratitis-Trifluridine 44. Herpes Simplex Orolabialis-Pancyclovir 45. Neonatal Herpes Simplex-Acyclovir 46. Pneumocystis carinii Pneumonia- Cotrimoxazole 47. Cystic Acne-Retinoic acid 48. Trigeminal Neuralgia-Carbamezapine 49. Actinomycosis-Penicillin 50. Plague- Streptomycin 51. Opioid Withdrawal- Methadone 2nd-Clonidine 52. Alcohol Withdrawal- Chlordiazepoxide 2nd-Diazepam 53. Post Herpetic Neuralgia- Fluphenazine 54. WEST Syndrome-ACTH 55. Diabetic Diarrhoea- Clonidine 56. Lithium Induced Neuropathy-Amiloride 57. Tetanus: PEN G Na; TETRACYCLINE; (DIAZEPAM 58. Diphteria: PEN G K; ERYTHROMYCIN 59. Pertusis: ERYTHROMYCIN; AMPICILLIN 60. Meningitis: MANNITOL (osmotic diuretic); DEXAMETHASONE (anti-inflammatory); DILANTIN/PHENYTOIN (anti-convulsive); PYRETINOL/ENCEPHABO L (CNS stimulant) 61. Cholera: TETRACYCLINE 62. Amoebic Dysentery: METRONIDAZOLE 63. Shigellosis: CO-TRIMOXAZOLE 64. Typhoid: CHORAMPHENICOL 65. Rabies: LYSSAVAC, VERORAB 66. Immunoglobulins: ERIG or HRIg 67. Malaria: CHLOROQUINE 68. Schistosomiasis: PRAZIQUANTEL 69. Felariasis: DIETHYLCARBAMAZINE CITRATE 70. Scabies: EURAX/ CROTAMITON 71. Chicken pox: ACYCLOVIR/ZOVIRAX 72. Leptospirosis: PENICILLIN; TETRACYCLINE; ERYTHROMYCIN 73. Leprosy: DAPSONE, RIFAMPICIN 74. Anthrax: PENICILLIN 75. Tuberculosis: R.I.P.E.S. 76. Pneumonia: COTRIMOXAZOLE; Procaine Penicillin 77. Helminths: MEBENDAZOLE; PYRANTEL PAMOATE 78. Meningitis: MANNITOL (dec. ICP) ; DEXAMETHASONE ( relieve cerebral edema) ; DIAZEPAM ( anticonvulsant) ; PENICILLIN 79. Syphilis: PENICILLIN 80. Gonorrhea: PENICILLIN Schedule Of Drugs “A” Performa for forms no. 1 to 50( Application, issue, renewal, etc.) “B” Rates of fee for test or analysis by CDL or Govt. analysts “C” List of Biological and special products (Injectable) applicable to special provisions. Ex. Sera, Vaccines, Penicillin…..etc “C1” List of Biological and special products (nonparenteral) applicable to special provisions. Ex. Digitalis, Hormones , Ergot “D” List of drugs that are exempted from provisions of import “E1” List of poisonous substances under the Ayurvedic , Siddha and Unani systems “F” Provisions applicable to blood bank “F1” Special provision applicable to biological and special products, eg. Bacterial and viral vaccines, sera from living animals, bacterial origin diagnostic agents “F2” Standards for surgical dressings “F3” Standards for umbilical tapes “FF” Standards for ophthalmic preparations “G” List of substances required to be used under medical supervision and labelled accordingly Ex. Metformin, Anti Histaminic, …etc “H” List of substances (prescription) that should be sold by retail only on prescriptions of R.M.P. Ex. Atenolol, Lorazepam, Dapson …etc

"Drugs And their active Metabolite" 1). Rifampicin - Desacetylated metabolite 2).Thioridazine - Mesoridazine 3). Quinidine - 3- hydroxy quinone. 4). propanolol - N- deisopropyl met. 5). Naloxsne - 6 hydroxy Naloxane. 6). Morphine - Nor morphine 7).Guanethidine - N- OXIDE 8). CODEINE - MORPHINE,. Nor Morphine 9). Amytryptylline - Nortryptalline 10).Carbimazole - Thiamazole "PRODUCTS AND ANIMALS USED FOR BIOASSAY" Drug product Animal 1). Atropine - Rabbit 🐰 2). Insulin inj. - Guinea pig 🐖 3). Antiseptic - FROG 🐸 and disinfectant 4). Glycogen - cat 🐈 5). Vasopressin - Rat 🐀 6). Heparin sod. - sheep 🐑 "Drug Of Choice" 1. Clonidine withdrawal 👉Phentolamine 2.Primary open angle glaucoma 👉Latanoprost 3. Breast cancer 👉Tamoxifen 4. Endometriosis 👉Danazol 5.Thyroid storm 👉Propylthiouracil 6.Acute Hyperkalemia 👉Calcium Gluconate 7.Severe Digitalis toxicity 👉DIGIBIND 8.Acute migraine 👉Sumatriptan 9.Kala azar 👉Liposomal amphotericin B 10.Iron poisoning 👉Desferrioxamine 11.VRSA 👉Linezolid 12.Alcohol poisoning 👉Fomepizole 13.Diabetic ketoacidosis 👉IVF "TABLETS AND CAPSULES MACHINE" 1. Rotosort:- 👉 for filled / unfilled capsule sorting machine and for de-dusting. 2. Rotofill:- 👉 to fill pellets in hard gelatin capsule 3. Rotoweigh:- 👉 A high speed capsule weighing machine. 4. Accogel:- 👉 filling of dry powder in soft gelatin capsule. 5. Accofill:- 👉fill exact powder dose in hard gelatin capsule 6. Wurster:- 👉for coating. 7. Osaka:- 👉capsule filling machine (powder, granules) 8. Zanasi:- 👉 filling (powder, pellets, tablets) 9. Lily / parke-davis :- 👉 capsule filling (powder) 10. Farmatic, holfiger & kary-liquid filling in HGC . 11. Erweka:- 👉 De-dusting and polishing capsule machine. 12. Seidender :- 👉Uses a Belt for visual inspection. 13. Vericap 1200:- 👉capsule weighing machine. "BETA ADRENERGIC BLOCKER" TRICK :- "THE NEPAL PM" 👉 TIMOLOL 👉 NADOLOL 👉 ESMOLOL 👉 PINDOLOL 👉 ATENOLOL 👉 LABETALOL 👉 PROPANOLOL 👉 METOPROLOL "IMPORTANT NOTES FOR PHARMACIST" 🧑‍🔬🧑‍🔬🧑‍🔬🧑‍🔬🧑‍🔬🧑‍🔬🧑‍🔬🧑‍🔬🧑‍🔬🧑‍🔬 SOME IMPORTANT MECHANISM OF ACTION 1. DNA Dependent RNA polymerase :- 👉 RIFAMPICIN 2. RNA Dependent DNA POLYMERASE:- 👉 Zidovudine 3. PROTEIN SYNTHESIS BLOCKER :- 👉 Erythromycin 👉 Chloramphenicol 👉 Tetracycline 4. ACE INHIBITORS :- 👉 Captopril 5. CALCIUM CHANNEL BLOCKER :- 👉 Nifedipine 👉 Diltiazem 6. COX INHIBITORS :- 👉 Aspirin 7. GABA FACILITATOR :- 👉 Benzodiazepines 8. Antimetabolites :- 👉 Methotrexate 9. Loop Diuretics :- 👉 Frusemide 10. GABA INHIBITORS :- 👉 Sodium valproate CLASSIFICATION OF DILUENTS 1. SUGAR :- 👉 Dextrose 👉 Lactose 👉 Sucrose 👉 Amylose 👉 Mannitol 👉 Sorbitol 👉 Inositol 2. POLYSACCHARIDES :- 👉 Starches 👉 Modified starch 👉 E.g. RX 1500 , Celutab etc. 👉 Cellulose 👉 Cellulose derivatives 👉 Microcrystalline cellulose (MCC). 3. INORGANIC COMPOUNDS :- 👉 Calcium phosphate dihydrate 👉 Calcium sulfate dihydrate 👉 Calcium lactate trihydrate 👉 Calcium carbonate 👉 Magnesium carbonate 👉 Magnesium oxide 4. MISCELLANEOUS COMPOUNDS :- 👉 Bentonite 👉 Polyvinyl pyrrolidone 👉 Kaolin 👉 Silicone derivatives DRUGS CHOICE 1. Algia(pain)/pyrexia- Paracetamol 2. Acute bronchial- asthma :- salbutamol 3. Acute gout :- NSAIDS 4. Acute hyperkalemia:- calcium gluconate 5. Severe DIGITALIS toxicity :-DIGIBIND 6. Acute migraine :- sumatriptan

3) Upper consulate temperature: Temperature above which two liquids get completely miscible, e.g. Phenol-water. 4) Lower consulate temperature: Temperature below which two liquids get completely immiscible, e.g. Triethyl amine water. 5) Syneresis: Shrinkage of gel by extrusion of liquid. 6) Draves test: Efficiency of wetting agent. 7) Pumice: Gas in solid. 8) Foam: Gas in liquid. 9) Bulges: Bentonite magma. 10) Spur: Procaine penicillin gel. 11) Schulze-Hardy rule: Precipitating power of oppositely charged ion. 12) Hofmeister Rank series: Precipitating power directly related to ability to separate water molecule. 13) Mark-Hou wink equation: Intrinsic viscosity. 14) Fanning equation: Energy loss due to friction. 15) Van der Waal’s equation: Real gases. 16) Clausius-Clapeyron equation: Heat of vaporisation. 17) Darcy equation: Filtration rate. 18)Instron tester: Tackiness and stickiness. 19) Cryoscopic constant: Freezing point depression (Beckmann apparatus). 20) Ebullioscopic constant: Elevation of boiling point. 21) Graham’s law: Diffusion of Gases. 22) Dalton’s law: Total vapour pressure. 23) Raoult’s law: Partial vapour pressure (Positive deviation: Benzene; Negative deviation: Acetone, chloroform) 24) Parachor: Liquid surface tension (sudgen constant). 25) Rabbit RBC’s: Standardisation of electrophoretic cells and zeta meter. "Some important Drugs and its side effects" Grey Baby Syndrome- Chloramphenicol Pin Point Pupil- Morphine Reyes Syndrome- Aspirin Urine Coloration- Rifampicin Frontal Headache- Indomethacin Captopril- Persistent dry cough Bleomycin- Pulmonary fibrosis Vancomycin- Red man syndrome Nicotinic acid- Flush Steven Johnsons syndrome Allopurinol sulphonamides- kernicterus aminoglycosides - ototoxicity discoloration of teeth- tetracycline doxorubicin & duanorubucin- cardiomyopathy. chloroquine- cardiotixicity doxycycline- esophageal ulceration vincristine & vinblastine- neuropathy cyclophosphamide- alopecia cimetidine & spironolactone- gynaecomastia pH Blood: 7.4 Skin: 7.4 Secretion of Skin: 5.5 Gastric juice: Infants: 5, Adults: 2 Saliva: 6.3-6.7 Urine: 4.4-8 Stool: aprox. 6 Bile Juice: 8-8.6 Semen: 7.2-8 Vagina: 3.8-4.5 Years Of Different Act : 1. Opium Act -1875 2. Poisonous Act -1919 3. Dangerous Drug Act -1930 4. Drug & Cosmetic Act Act – 1940 & Rule – 1945 5. Factory Act - 1949 6. Pharmacy Act -1948 7. Pharmacy Council Of India {PCI} -1949 8. Drug & Magic Remedies - 1954 9. Medical & Toilet Preparation Act – 1955 & Rule – 1956. 10. Patent Act -1970 11. Medicinal Termination & Pregnancy Act - 1971 12. GMP - 1975 13. Narcotic & Psychotropic Act -1985 14. Drug Price Control Order - 1995 15. The All India Council For Technical Education Act -1994 16. First ICH Indian Pharmacopoeia -1989 17. 1 st Edition IP - 1955 18. 2 nd Edition IP -1966 19. 3 rd Edition IP -1985 20. 4 th Edition IP -1996 21. 5th Edition IP - 2007 22. 6th Edition IP - 2010 23. 7th Edition IP - 2014 24. 8th Edition IP - 2018 > Rx = Treatment > Hx = History > Dx = Diagnosis > q = Every > qd = Every day > qod = Every other day > qh = Every Hour > S = without > SS = One & half > C = With > SOS = If needed > AC = Before Meals > PC = After meals > BID = Twice a Day > TID = Thrice a Day > QID = Four times a day > OD = Once a Day > BT = Bed Time > hs = Bed Time > BBF = Before Breakfast > BD = Before Dinner > Tw = Twice a week > SQ = sub cutaneous > IM = Intramuscular > ID = Intradermal > IV = Intravenous > Q4H = (every 4 hours) > QOD = (every other day) > HS= (at bedtime) > PRN = (as needed) > PO or "per os" (by mouth) > Mg = (milligrams) > Mcg/ug = (micrograms) > G or Gm = (grams) > 1TSF (Teaspoon) = 5 ml > 1 Tablespoonful = 15ml > DDx = differential Diagnosis > Tx = Treatment > RTx = Radiotherapy > CTx = Chemotherapy > R/O = rule out > s.p = status post > PMH(x) = post medical history > Px = Prognosis > Ix = Indication > CIx = contraindication > Bx = biopsy > Cx = complication...

pharmacy knowledge YouTube channel Must read these specific notes before appearing any government pharmacist exam or any Pharmacist interview 👇 Specific antidotes for certain drugs: DRUG. ANTIDOTE 1.Paracetamol -- N-acetyl cysteine 2. Atropine. -- Physostigmine, Neostigmine. 3. Organophosphates -- Atropine, Prolidoxime 4. Barbiturates -- Sodium bicarbonate 5. Benzodiazipines -- Flumagenil 6. Amphetamine -- Ammonium chloride 7. Opioids -- Naloxone 8. Digoxin -- Digibind 9. Heparin -- Protamine sulphate 10. Warfarin -- Vit. K 11. Beta blockers -- Glucagon 12. Carbon monoxide -- 100% Oxygen "HERBAL DRUGS " that are used in diff. pathological conditions:- 1. Liquorice :- anti-ulcer 2. Ipecac - emetic 3. Hyoscine,Cannabinoids: - anti-emetic 4. Senna, Cascara, Castor oil :- treatment of constipation 5. Gum guggul: - anti-rheumatic 6. Colchicum :- Anti-gout 7. Guggul lipids, Garlic, Oats: - Anti-atherosclerotic 8. Ephedra, Gingkoside B, Theophylline :- Anti -asthmatic 9. Vinca, Taxanes, Podophyllotoxins - Anti-cancer 10. Artemesinin derivatives: - Anti-malarial "DRUGS BOUND TO PLASMA" PROTEIN To Albumin - To α1-acid glycoprotein Barbiturates - β-blockers NSAIDs - Bupivacaine Valproic acid. - Lignocaine Phenytoin. - Disopyramide Penicillin’s - Imipramine Sulfonamides - Methadone Tetracyclines - Prazosin Tolbutamide - Quinidine Warfarin - Verapamil "SCIENTISTS’ CONTRIBUTION" 1. Father of Medicine:- Hippocrates 2. Father of Pharmacy:- Prof. William Procter 3. Father of Pharmacy (India):- Prof. Mahadeva Lal Schroff 4. Father of Modern Pharmacology:- Oswald Schmiedeberg 5. First Pharmacist:- Louis Heberg 6. First Physician:- Galen "List of orphan drugs" (acronym : “SAD SO FAR”) • Somatotropin • Ancrod • Digoxin • Succimer / Sodium nitrite • LiOthyronine • Fomepizole • Amphotericin B • Rifabutin "Parts of prescription" Description 1.Superscription. - Symbol Rx 2.Inscription. -Formula / Dosage form 3.Subscription - Direction to Pharmacist 4. Signatura - Direction to patient "Suppositories" Base Examples :- 1.Water soluble base :- Macrogols, Soap glycerine 2.Oleaginous base:- Theobroma oil/ Cocoa butter, Palm kernel oil 3 Emulsifying base:- Witepsol DISPENSING OF MEDICATION DOSAGE FORMS 1. Elixirs: Hydroalcoholic (alcohol NMT 40%) sweet solution for oral use. 2. Linctuses: Monophasic liquid with high concentration of syrup for treatment of cough. 3. Draughts: Monophasic liquid taken as a single dose orally. 4. Paints: Viscous preparation for local action in pharynx. 5. Glycerites: Viscous, hygroscopic solution of medicament applied externally. 6. Sprays: Aqueous or non-aqueous monophasic liquids spraying in throat/nose. 7. Ear drops: Solution, suspension, emulsion remove excessive cerumen (ear wax). 8. Liniment: Solution or emulsion in aqueous/oily vehicle massage to unbroken skin. “FOR EXTERNAL USE ONLY”. 9. Lotions: Emulsion, suspension or combination of both or aqueous/non-aqueous solution. “APPLY ON UNBROKEN SKIN”. 10. Tablet triturates: Drug + Diluent + Alcohol “USED FOR SUBLINGUAL / ORAL USE”. 11. Lozenges: Hard and intended to be sucked. 12. Pills: Small spherical for internal use. Veterinary use pills are called as “BOLUS”. 13. Poultices: Pasty preparation applied hot onto the skin, to reduce inflammation. 14. Gargles: “NOT TO BE SWALLOWED IN LARGE AMOUNT”. "IMPORTANT TERMS TO REMEMBER" 1) Kraft point: Temperature at which solubility of surfactant equal to CMC. 2) Cloud point: Temperature above which cloudiness occurs.

https://youtu.be/zN2c4bQKVvk?si=Yzqontz6O_6oq686 633 Post Permanent Pharmacist Vacancy / Fresher Candidate Eligible 👍 साल 2024 की सबसे बड़ी Pharmacist Vacancy / Eligibility ? Exam date ? Exam Syallabus & Scheme ? Complete Details ✅

https://youtu.be/cL9GeDX_ydM?si=n9_UUpE60HQ9U-HV 56 Post Permanent Pharmacist Vacancy at food and drug administration / Fresher Candidate Eligible