Pharmacy study materials 📕📚

IMPORTANT NOTES FOR GPAT🏃🏃🏃🏃🏃🏃🏃🏃🏃 “Important pH_values” 👉🏻Ph value of water = 7 👉🏻 pH value of milk = 6.4 👉🏻 pH value of vinegar = 3 👉🏻 pH value of human blood = 7.4 👉🏻 pH value of lemon = 2.4 👉🏻 pH value of NaCl = 7 👉🏻 pH value of alcohol = 2.8 👉🏻 pH value of human urine = 4.8-8.4 👉🏻pH value of seawater = 8.5 👉🏻pH value of tear = 7.4 👉🏻 pH value of human saliva = 6.5-7.5 “pH values of few acids” 👉🏻pH value of HCL = 0 👉🏻 pH value of H2SO4 = 1.0 👉🏻Apple, soda's pH value = 3.0 👉🏻 pH value of pickle = 3.5-3.9 👉🏻Tomato's pH value = 4.5 👉🏻Banana pH value = 4.5-5.2 👉🏻 pH value of acid rain = around 5.0 👉🏻Bread's pH value = 5.3-5.8 👉🏻pH value of red meat = 5.4 to 6.2 👉🏻pH value of charred cheese = 5.9 👉🏻 pH value of butter = 6.1 to 6.4 PH value of fish = 6.6 to 6.8 Other basicity list: 👉🏻 pH value of shampoo = 7.0 to 10 👉🏻Baking soda (sodium bicarbonate) pH value = 8.3 👉🏻Toothpaste pH value = 9 PH value of magnesia milk = 10.5 👉🏻Ammonia pH value = 11.0 👉🏻 pH value of hair stroking chemicals = 11.5 to 14 👉🏻 pH value of lime (calcium hydroxide) = 12.4 👉🏻 pH value of lye = 13.0 👉🏻 pH value of sodium hydroxide (NaOH) = 14.0 YOU CAN SHARE THIS IMPORTANT NOTES AND YOU CAN JOIN OUR CHANNEL... 👉👉👉👉👉 @pharmacystudymaterials

DRUGS OF CHOICE 1. Algia(pain)/pyrexia- Paracetamol 2. Acute bronchial- asthma :- salbutamol 3. Acute gout :- NSAIDS 4. Acute hyperkalemia:- calcium gluconate 5. Severe DIGITALIS toxicity :-DIGIBIND 6. Acute migraine :- sumatriptan 7. Cheese reaction :- phentolamine 8. Atropine poisoning :- physostigmine 9. Cyanide poisoning :- amyl nitrite 10. Benzodiazepine poisoning:- flumazenil 11. Cholera :- tetracycline 12. KALA-AZAR :- lipozomal amphotericin- B 13. Iron poisoning :- desferrioxamine 14. MRSA :- vancomycin 15. VRSA :- LINEZOLID 16. Warfarin overdose :- vitamin-K 17. OCD :- fluoxetine 18. Alcohol poisoning :- fomepizole 19. Epilepsy in pregnency :- phenobarbitone 20. Anaphylactic shock :- Adrenaline 21. MRSA Infection-Vancomycin 22. Malaria in Pregnancy-Chloroquine 23. Whooping Cough or Perteusis- Erythromycin 24. Kawasaki disease-IV 25. Warfarin Overdose-Vit-K @pharmacystudymaterials

Important things to remember: 1. BP: 120/80 2. Pulse: 70-100 3. Temperature: 36.8-37 4. Breathing: 12-16 5. Hemoglobin: Male -13.50-18 Women - 11.50-16 6. Cholesterol: 130-200 7. Potassium: 3.50-5 8. Sodium: 135-145 9. Triglycerides: 220 10. Body Blood Volume: PCV 30-40% 11. Sugar Levels: For Children (70-130) For Adults: 70-115 12. Iron: 8-15 mg 13. White blood cells WBC: 4000-11000 14. Platelets: 1,50,000 - 4,00,000 15. Red blood cells RBC:4.50-6 million. 16. Calcium: 8.6 -10.3 mg/dL 17. Vitamin D3: 20 - 50 ng/ml. 18. Vitamin B12: 200-900 pg/ml.

💊Schedule Of Drugs💊 “A” Performa for forms no. 1 to 50( Application, issue, renewal, etc.) “B” Rates of fee for test or analysis by CDL or Govt. analysts “C” List of Biological and special products (Injectable) applicable to special provisions. Ex. Sera, Vaccines, Penicillin…..etc “C1” List of Biological and special products (nonparenteral) applicable to special provisions. Ex. Digitalis, Hormones , Ergot “D” List of drugs that are exempted from provisions of import “E1” List of poisonous substances under the Ayurvedic , Siddha and Unani systems “F” Provisions applicable to blood bank “F1” Special provision applicable to biological and special products, eg. Bacterial and viral vaccines, sera from living animals, bacterial origin diagnostic agents “F2” Standards for surgical dressings “F3” Standards for umbilical tapes “FF” Standards for ophthalmic preparations “G” List of substances required to be used under medical supervision and labelled accordingly Ex. Metformin, Anti Histaminic, …etc “H” List of substances (prescription) that should be sold by retail only on prescriptions of R.M.P. Ex. Atenolol, Lorazepam, Dapson …etc “J” List of diseases and ailments that drug should not claim to cure Ex. Cancer, AIDS, Cataract, Diabetes…etc “K” List of drugs that are exempted from certain provisions regarding manufacture “M” Requirements of manufacturing premises, GMP requirements of factory premises, plants and equipments “M1” Requirements of factory premises for manufacture of Homeopathic medicines “M2” Requirements of factory premises for manufacture of cosmetics “M3” Requirements of factory premises for manufacture of medical devices “N” List of equipment to run a Pharmacy “O” Standards for disinfectant fluids Ex… Phenol, H2O2, alcohol…. “J” List of diseases and ailments that drug should not claim to cure Ex. Cancer, AIDS, Cataract, Diabetes…etc “K” List of drugs that are exempted from certain provisions regarding manufacture “M” Requirements of manufacturing premises, GMP requirements of factory premises, plants and equipments “M1” Requirements of factory premises for manufacture of Homeopathic medicines “M2” Requirements of factory premises for manufacture of cosmetics “M3” Requirements of factory premises for manufacture of medical devices “N” List of equipment to run a Pharmacy “O” Standards for disinfectant fluids Ex… Phenol, H2O2, alcohol…. “P” Life period(expiry) of drugs Ex. Insuline Inj. – 24 months “Q” Coal tar colors permitted to be used in cosmetics Ex. Caramel, TiO2, Toney red….. “R” Standards for mechanical contraceptives “R1” Standards for medical devices “S” Standards for cosmetics “T” Requirements (GMP) of factory premises for Ayurvedic, Siddha, Unani drugs “U” Manufacturing and analytical records of drugs “U1” Manufacturing and analytical records of cosmetics “V” Standards for patent or proprietary medicines “W” List of drugs marketed under generic names- Omitted “X” List of narcotic drugs and psychotropic substances EX. Opium, Morphine, Barbital…… “Y” Requirement and guidelines on clinical trials for import and manufacture of new drugs.. @pharmacystudymaterials

✍️📒 *CANCER* 📖✍️ ◆ *Introduction to cancer* 👇 -Cancer is a group of diseases involving abnormal cell growth -with the potential to invade or spread to other parts of the body. - These contrast with benign tumors, which do not spread ◆ *Possible signs and symptoms* include:-👇 -lump, -abnormal bleeding, -prolonged cough, -unexplained weight loss -change in bowel movements. -While these symptoms may indicate cancer. -they can also have other causes. -Over 100 types of cancers affect humans. ◆ *Cancer Other names* -Malignant tumor, -malignant neoplasm -Tumor Mesotheliomalegend •A coronal CT scan showing a malignant mesothelioma ●Legend: → tumor ←, ✱ central pleural effusion, 1 & 3 lungs, 2 spine, 4 ribs, 5 aorta, 6 spleen, 7 & 8 kidneys, 9 liver ◆ *Risk factors*👇 -Tobacco, - obesity, -poor diet, -lack of physical activity, -excessive alcohol, -certain infections ◆ *Treatment*👇 -Radiation therapy, -surgery, -chemotherapy, and -targeted therapy. ◆ *Drugs:-*👇 - Mechlorethamine, - Thiotepa, - Methotrexate, - Vincristine, - Vinblastine, - Daunarubicin - samrubicin - Carmustine - Busulphan etc.

Vitamins

Important Tests : 1. Adom test - Scoliosis 2. Allen test - ABG Analysis 3. Aldehyde test - Leprosy 4. Phosphate test - Pasteurization 5. Patch test - Allergic Reaction 6. Tourniquet test - Dengue 7. Urea Breath test - H.Pylori 8. Schick test - Diphtheria 9. Dick test - Scarlet Fever 10. Rothers test - Acetone in Urine 11. Hey test - Bile Salt Urine 12. Smith test - Bile Pigment Urine 13. Benedict test - Urine Glucose 14. Kveim test - Sarcoidosis 15. Rinne & Webber test - Hearing 16. Direct Coomb test - Hemolytic Anemia 17. Ischiara test - Color Vision test 18. Snellen Chart test - Distance Vision 19. Confrontation test - Central and Peripheral Vision 20. Jegar's type Card test - Near Vision 22. Schiling test - Vitamin B12 Absorption 23. Histamine test - Leprosy 24. Roller Over test - Pre-Eclampsia 25. Fern Test or Nitrizine test - leakage of Amniotic fluid 26. VDRL test - Syphilis 27.VMA (Vanellyl Mandelic Acid) - Pheochromocytoma 28. Glucose Tolerance test - Diabetes Mellitus 29. Glycosylated Hemoglobin /Hb1AC test - Diabetes Mellitus 30. Water Deprivation test - Diabetes Insipidus 31. Treadmill / Stress test - Heart Function 32. Triple test - Down Syndrome 33. D-Dimer test - Measuring Clot formation (DVT, PE, DIC) 34. Trendelenburg test - VericoseVein 35. Phallen / Tinnel test -Carpal Tunnel Syndrome 36. Gold QuntiFeron test -Tuberculosis 37. Bangle Test - Protein Energy Malnutrition 38. Tensilon test -Myasthenia Gravis 39. Romberg test -Neurological Function / Balance or Gait 40. Knee Kiss test -Meningitis in Children 41. Tzank test - Herpes Genital or Vericella 42. Frie test -Lymphogranuloma inguinale 43. Widal test - Typhoid (on2ndweek) 44. Weilfelix test - Typhoidfever 45. Bonny test / Marshall test - Stress Incontinence 46. Binnet test - Intelligence Quotient 47. Sweat Chloride test - Cystic fibrosis 48. Hanging Drop test - Cholera 49. Paul Bunnel test - Epstien Barr Virus 50. Shake test / Bubble test - Surfactant and Fetal Lungs Maturity 51. Rubin test - Patency of Fallopian Tube 52. Tape test - Pin Worm 53. Ortho Tolidin test - Check Chlorine in Water 54. Dexa Scan - Bone Metabolic Disease (eg.Osteoporosis) 55. Heel to Shin test - Body Coordination Test 56. Halo test - CSF Leakage 57. Dexamethasone Suppression test - ACTH or Pituitary / Adrenal Gland Tumor 58. Arthrocentesis - Joint Inflammation and Infection 59. Holter Monitoring - 24 Hours ECG Monitoring in Dysarhythmia 60. Pulmonary Function test - Measure Lung Volume and Capacity (By-Spirometer) 61. SGOT & SGPT (AST/ALT) - Liver Function Test 62. PAP’s Smear - Cancer of Cervix 63. Creatinine Clearance test - Estimation of GFR 64. Wood's Light Examination - Superficial Infection of Skin 65. Burrow Ink test - Scabies / The Itch 66. Braden Scale - To Measure integrity of Bed sore @medx101

कमी वयात जेवढी मेहनत घ्याल.. तितका जास्त आयुष्याचा आनंद घेता येईल 👍📚👌

MENOPAUSE TREATMENT. Hormone replacement therapy, Anti-estrogens, Birth control pills. https://youtu.be/ui5J_Tvl11Q

SUPERINFECTION It refers to the appearance of a new infection as a result of antimicrobial therapy. Normal microbial flora contributes to host defense by development of bacteriocins. Pathogens also have to compete with the normal flora for nutrients. Broad spectrum antibiotics (tetracyclines, chloramphenicol, clindamycin, aminoglycosides and ampicillin) may kill the normal flora and result in the development of new infection. Superinfection is more commonly seen in immunocompromised patients. Oropharynx, intestine, respiratory and genitourinary tracts are common sites for the development of new infection. The organisms frequently involved are Candida albicans, Clostridium difficile, staphylococci, proteus and pseudomonas. Clostridium difficile superinfection may result in pseudomembranous colitis (most commonly due to third generation cephalosporins). Oral vancomycin is the drug of choice for pseudomembranous colitis (alternative drugs are fidaxomicin and metronidazole). Recently, a monoclonal antibody against C. difficile toxin B (Bezlotoxumab) has been approved to reduce the recurrence of C. difficile infection. Further, due to the loss of commensal flora, there may be decreased formation of vitamin K leading to enhanced anticoagulant effects of warfarin.

Tetracyclines are first choice drugs for • Lymphogranuloma venereum (LGV) • Granuloma inguinale • Atypical pneumonia due to chlamydia (Now preferred drug is azithromycin) • Cholera • Brucellosis (with rifampicin) • Relapsing fever (Doxycycline) • Plague prophylaxis (Drug of choice for treatment is streptomycin) • Lyme’s disease (Doxycycline) • Rickettsial infections (Doxycycline) • Chlamydial infections (Doxycycline)

CSIR-UGC-NET Exam will be in the September 2022