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The correct answer is Kussmaul sign. 
๐Ÿฉบ Explanation
โ–ถ๏ธ Kussmaul sign:   - Defined as a paradoxical rise in jugular venous pressure (JVP) during inspiration.   - Normally, inspiration decreases intrathoracic pressure โž” increases venous return โž” lowers JVP.    - In conditions like constrictive pericarditis, restrictive cardiomyopathy, or right-sided heart failure, the right ventricle cannot accommodate the increased venous return. This leads to a rise in JVP instead.    โžฒ Homan sign โž” calf pain on dorsiflexion of the foot, associated with deep vein thrombosis.   โžฒ Murphy sign โž” inspiratory arrest due to pain on palpation of the right upper quadrant, seen in acute cholecystitis.   โžฒ Trousseau sign โž” carpopedal spasm induced by inflating a blood pressure cuff, seen in hypocalcemia. 
๐Ÿ”‘ Clinical Pearl
Kussmaul sign is a bedside clue to impaired right ventricular filling. It helps differentiate constrictive pericarditis (positive Kussmaul sign) from cardiac tamponade (usually absent Kussmaul sign).
๐Ÿ’Ž @profmedken | @MedkenHub

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๐Ÿ’Ž @profmedken | @MedkenHub
๐Ÿ’Ž @profmedken | @MedkenHub
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๐Ÿ’Ž @profmedken | @MedkenHub
๐Ÿ’Ž @profmedken | @MedkenHub
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WHO 2026: Routine central line replacement is outโ€”clinical indication is in. #CentralLine
WHO 2026: Routine central line replacement is outโ€”clinical indication is in. #CentralLine
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Hypokalemia vs. Hyperkalemia #ECG
Hypokalemia vs. Hyperkalemia #ECG
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ECG Rhythm Comparison โžซ Hyperkalemia โžซ Hypokalemia โžซ Hypercalcemia โžซ Hypocalcemia #ECG
ECG Rhythm Comparison โžซ Hyperkalemia โžซ Hypokalemia โžซ Hypercalcemia โžซ Hypocalcemia #ECG
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ECG Rhythms (Simple Comparison) #ECG
ECG Rhythms (Simple Comparison) #ECG
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๐Ÿง  Empty Delta Sign โ€” A Classic Clue to Cerebral Venous Sinus Thrombosis A patient presents with severe headache, seizures, p
๐Ÿง  Empty Delta Sign โ€” A Classic Clue to Cerebral Venous Sinus Thrombosis A patient presents with severe headache, seizures, papilledema, or focal neurologic deficits. Contrast imaging reveals the classic โ€œempty delta signโ€ โ€” a triangular filling defect within the dural venous sinus. ๐Ÿ‘‰ This is a hallmark of Cerebral Venous Sinus Thrombosis (CVST), most commonly involving the superior sagittal sinus. โš  Early recognition is critical because delayed diagnosis can lead to venous infarction, hemorrhage, and raised intracranial pressure. ๐Ÿ’Ž @profmedken | @MedkenHub #Neurology #Radiology #CVST #Neuroradiology #MedEd
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Dr. Howard Tucker has been awarded the record title for the oldest doctor ever after working until the age of 103. He was con
Dr. Howard Tucker has been awarded the record title for the oldest doctor ever after working until the age of 103. He was continuing to work as a neurologist until just two months before his passing on 22 December 2025. ยฉ guinnessworldrecords ๐Ÿ’Ž @profmedken | @MedkenHub
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Explanation The answer is B. The guidelines of ACCP divide each of the main indications for anticoagulation (mechanical heart valves, AF and thromboembolic disease) into three risk categories (high, medium and low risk) according to the probability of thromboembolism. Any mitral valve prosthesis, for example, is considered high-risk. The guidelines recommend that high-risk patients should receive โ€˜bridgingโ€™ anticoagulation whilst not covered by vitamin K antagonists. โž  First choice is high-dose (LMWH) continuing up to 24 hours before surgery. โž  Unfractionated heparin by infusion up to 4 hours before surgery is considered an acceptable alternative, but much less convenient. โž  Low-dose LMWH would not be considered sufficient for high-risk patients. โž  Oral anticoagulants may be safely restarted 12โ€“24 hours after surgery since the time to peak effect is delayed. High-dose LMWH may be delayed until 48โ€“72 hours post procedure to mitigate bleeding concerns. โž  Discontinuing anticoagulants without implementing bridging therapy would be inappropriate for this patient, since he is at high risk of thromboembolic phenomena. A 4-hour delay between high-dose LMWH and surgery is too short due to the hemorrhagic risk involved. ๐Ÿ’Ž @profmedken | @MedkenHub
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๐Ÿ”˜ ๐Œ๐‚๐290 A 61-year-old gentleman attends the anesthetic preoperative clinic. He is due to attend for a total knee replacement in 6 weeksโ€™ time. His past medical history includes a mechanical mitral valve replacement 5 years previously and he is on warfarin. It is decided to discontinue his warfarin 5 days preoperatively. Select the anticoagulation strategy most appropriate for this patient in the 5 days before surgery: A. Leave the patient off all anticoagulants because of the high bleeding risk. B. Give therapeutic dose subcutaneous low molecular weight heparin daily, administering the last dose 24 hours before surgery. C. Give therapeutic dose subcutaneous low molecular weight heparin daily, with the last dose 12 hours before surgery. D. Give continuous intravenous unfractionated heparin and stop 4 hours before surgery. E. Give low-dose (prophylactic dose) subcutaneous low molecular weight heparin, administering the last dose 24 hours before surgery. ๐Ÿ’Ž @profmedken | @MedkenHub
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๐Ÿ”˜ ๐Œ๐‚๐289 A septic patient has a central venous pressure of 10 mm Hg, a blood pressure of 80/40 mm Hg, and a pulse rate of 96 beats/min. The best agent to treat the hypotension is
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๐Ÿ”˜ ๐Œ๐‚๐288 The femoral nerve lies
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Explanation The answer is D. The lungs degrade and inactivate catecholamines rather than synthesizing epinephrine from norepinephrine. Options A, B, C, and E are all established metabolic functions of the lungs. ๐Ÿ’Ž @profmedken | @MedkenHub
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๐Ÿ”˜ ๐Œ๐‚๐287 Ondansetron causes its antiemetic effect by acting as an
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๐Ÿ”˜ ๐Œ๐‚๐286 ๐Ÿ’Ž @profmedken | @MedkenHub
๐Ÿ”˜ ๐Œ๐‚๐286 ๐Ÿ’Ž @profmedken | @MedkenHub
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๐Ÿ”˜ ๐Œ๐‚๐285 Which of the following is not seen as a result of primary renal disease in patients with chronic renal failure?
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๐Ÿซ€ NSTEMI vs STEMI โ€“ ECG Quick Guide ๐Ÿ”น 1. NSTEMI (Non-ST Elevation Myocardial Infarction) โ€ข Subendocardial ischemia (partial thickness damage) โ€ข ๐Ÿ”ป ST depression on ECG โ€ข ๐Ÿ”ป May show T wave inversion โ€ข Blood flow is reduced but not completely blocked โ€ข Serious condition, but less severe than STEMI ๐Ÿ”น 2. Acute Subendocardial Ischemia (NSTEMI Type) โ€ข Similar to NSTEMI โ€ข ๐Ÿ”ป T wave inversion is more prominent โ€ข Indicates ongoing ischemia โ€ข Requires urgent medical evaluation ๐Ÿ”น 3. STEMI (ST Elevation Myocardial Infarction) โ€ข Transmural ischemia (full thickness damage) โ€ข ๐Ÿ”บ ST elevation on ECG โ€ข Caused by complete coronary artery blockage โ€ข ๐Ÿšจ Medical emergency โ€“ immediate treatment needed ๐Ÿ”น 4. Normal ECG โœ”๏ธ Normal P wave, QRS complex, and T wave โœ”๏ธ ST segment is flat (isoelectric) โ€ข No signs of ischemia or infarction โšก Key Difference โ€ข NSTEMI โž” ST (Depression) โ€ข STEMI โž” ST (Elevation) ๐Ÿ“Œ Clinical Importance โ€ข Early ECG recognition can save lives โ€ข STEMI โž” Immediate reperfusion (PCI or thrombolysis) โ€ข NSTEMI โž” Medical management + risk assessment ๐Ÿ’Ž @profmedken | @MedkenHub #ECG #STEMI #NSTEMI #Cardiology
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๐Ÿซ€ NSTEMI vs STEMI โ€“ ECG Quick Guide ๐Ÿ’Ž @profmedken | @MedkenHub #ECG #STEMI #NSTEMI #Cardiology
๐Ÿซ€ NSTEMI vs STEMI โ€“ ECG Quick Guide ๐Ÿ’Ž @profmedken | @MedkenHub #ECG #STEMI #NSTEMI #Cardiology
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