MedPharm || طبصيدلة

About the pharmacological treatment for population suffering from depression. Which of the following statements about the selective serotonin reuptake inhibitors (SSRI) do you consider correct? a- Because of their relative safety at regular doses and improved tolerability compared with earlier agents, they are considered the first line of treatment for depression disorder. b- Citalopram and escitalopram may cause an increase In the QT interval at doses above 50 mg/day. c- The pharmacokinetics of SSRI are greatly affected by how well the kidneys are working and how old the person is. d- A 5-week washout after fluoxetine discontinuation critical before starting an TCA. e- Weight loss is one of the primary side effects for SSRI. SSRI.

In regard to diagnosis of depression. Which one of the followings is the Diagnostic Criteria for Major Depressive Episode? A-At least five symptoms must be consistently present (nearly every day) over a 2-week period B-At least two symptoms must be consistently present (nearly every day) over a 2-week period c-At least five symptoms must be consistently present (nearly every day) over a 6-week period D-At least two symptoms must be consistently present (nearly every day) over a 5-week period E- At least five symptoms must be intermittently present over a 2-week period