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🔰 Drugs that can cause drug-induced lupus:
• Procainamide (highest risk)
• Hydralazine
• Isoniazid (INH)
• Quinidine
• Methyldopa
• Anti-TNF-α agents (Infliximab, Etanercept, Adalimumab)
🔹Anti-histone antibodies: Positive (classic marker)
🔹Symptoms resolve after stopping the offending drug, though autoantibodies may persist for months.
Differentiate insulinoma from sulfonylurea abuse by Plasma / urine sulfonylurea screen.
A 31-year-old female nurse who is histrionic has episodes of severe hypoglycaemia, what lab value should you measure ?
A 12 year old boy attends A&E with pain after falling off his bicycle. A lateral X- ray of his wrist shows a fracture at the distal radius with the distal fracture fragment displaced anteriorly. What is the SINGLE most likely diagnosis?
A. Dinner fork deformity
B. Cubitus valgus
C. Gunstock deformity
D. Garden spade deformity
E. Coxa Vara
A 60 year old female has pain and stiffness in her right hip joint. The pain has been worsening over the past 6 months. The pain increases in intensity as the day progresses and it is usually least pain in the morning. She has noticed
nodules in the joints of the fingers of her hands. A recent blood test shows:
Haemoglobin 92 g/L
White cell count 9.8 x 109/L
Platelets 250 x 109/L
What is the SINGLE most likely diagnosis?
A. Rheumatoid arthritis
B. Osteoarthritis
C. Gout
D. Pseudogout
E. Multiple myeloma
