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St. Paul's Hospital Millennium Medical College Library Digital Library address 👉http://10.80.80.90 Institutional Repository Address 👉http://10.80.90.102

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WPS Office: Complete office suite with PDF editor Here's the link to the file: https://eu.docworkspace.com/d/sINSv3LX_AZ6-0bIG Shared from WPS Office: https://kso.page.link/wps
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Exam Reservation for Residents, C1, C2, & national exams @sphlibrary May 15 (Morning) May 17 (Afternoon- Emer Tech) May 18  (Morning- Anesth- R1) May 21 - 24 (Licensure exam) June 3  (Morning-Surg- R1 & Afternoon- Gyne- C1) June 5 (Afternoon- C1- IM) June 6   (Morning- IM) June 7  (Morning -Surg- C1)
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Medscape Medical News Do Multivitamin Supplements Lower Mortality Risk in CRC? Deepa Varma February 13, 2024 TOPLINE: Multivitamin supplements at a moderate dose appear to lower the risk for both all-cause and cancer-related mortality in patients with colorectal cancer (CRC); however, high doses of multivitamin supplements may increase the risk for CRC-specific mortality. METHODOLOGY: Some studies suggest that multivitamin supplements might increase a person's risk for CRC, and other research indicates that certain components of multivitamins, such as vitamins C and D, may have anti-CRC properties. Because as many as half of CRC survivors take a multivitamin, researchers wanted to assess whether multivitamin use affects overall survival among people with CRC. In the current prospective cohort study, researchers evaluated the use and dose of multivitamin supplements in 2424 patients with stages I-III CRC, using detailed information from patients in the Nurses' Health Study and Health Professionals Follow‐Up Study. The participants completed a mailed questionnaire every 2 years, which included questions about the current use of multivitamin supplements as well as doses per week (0, 1-2, 3-5, 6-9, and ≥ 10 tablets). The researchers assessed the potential association between multivitamin use and CRC-related as well as all‐cause mortality. TAKEAWAY: Over a median follow-up period of 11 years, 1512 deaths and 343 cancer-specific deaths occurred. For patients diagnosed with CRC, a moderate dose of multivitamins (three to five tablets per week) vs no multivitamin use was associated with a 45% lower risk for cancer-related mortality (adjusted hazard ratio [aHR], 0.55; P = .005). Moderate multivitamin use was also associated with a lower risk for all-cause mortality (aHR, 0.81; P = .04) as was a higher dose of six to nine tablets per week (aHR, 0.79; P < .001). However, high doses of 10 or more tablets per week were associated with a 60% higher risk for cancer-related mortality (aHR, 1.60; P = .02). IN PRACTICE: The study findings suggested that moderate multivitamin supplement use may come with a survival benefit in patients with CRC, while high doses may not, but "further studies are needed before making clinical recommendations for multivitamin use in patients with CRC," the authors said. SOURCE: This work, led by Ming‐ming He of Sun Yat‐sen University Cancer Center, Guangzhou, China, was published in Cancer. LIMITATIONS: Given the study's observational design, residual confounding may be possible. Reverse causation and recall bias are also possible limitations.
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World Hypertension Day World Hypertension Day is celebrated on May 17th each year to raise awareness about high blood pressure and its dangers. Hypertension, or high blood pressure, is a common condition that can lead to serious health complications such as heart disease, stroke, and kidney failure. The goal of World Hypertension Day is to encourage people to get their blood pressure checked regularly, adopt a healthy lifestyle, and seek treatment if needed to prevent complications. Awareness campaigns, health screenings, and educational programs are often organized on this day to promote hypertension awareness and prevention.
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Exam Reservation for Residents and C1 @sphlibrary May 15 (Morning) May 17 (Afternoon) May 18 (Morning) June 3 (Morning & Afternoon) June 6 (Morning)
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Medscape Medical News Toothbrushing in Hospital Reduces Infections and Death Elena Riboldi January 12, 2024 Daily toothbrushing is associated with a reduced incidence of hospital-acquired pneumonia (HAP), especially in patients on mechanical ventilation. This practice also is associated with lower intensive care unit (ICU) mortality, shorter ICU admissions, and shorter ventilator dependency. These are the findings of a meta-analysis published in JAMA Internal Medicine. Hospital policies must reassess the importance of oral hygiene even, or perhaps especially, in situations in which attention is focused elsewhere. Oral Microbiota and Lungs: HAP largely results from the aspiration of microorganisms present in the oral cavity. In fact, the oral microbiota comprises an estimated 700 species of bacteria, fungi, viruses, and protozoa. There is a known link between oral health and the development of pneumonia, and rigorous oral hygiene is part of the recommendations for preventing HAP. But the methods that should be used for ensuring good hygiene haven't been determined. The use of chlorhexidine-based mouthwash is debated because there is no evidence that it prevents pneumonia and because some studies have suggested a link between chlorhexidine and higher mortality rates. Toothbrushing is potentially more effective than antiseptic at reducing the oral microbiota because the mechanical action breaks up plaque and other biofilms. Yet, guidelines have focused very little on brushing as a measure for preventing hospital-acquired infections, meaning that every hospital has its own way of doing things. What Data Show: Selina Ehrenzeller, MD, and Michael Klompas, MD, MPH, of the Department of Population Medicine at Harvard University in Cambridge, Massachusetts, conducted a systematic literature analysis to identify randomized clinical studies in which daily toothbrushing was shown to affect the risk for HAP in adult hospital inpatients. Fifteen studies met the inclusion criteria and were used for the meta-analysis. The effective population size was 2786 patients. Daily toothbrushing was associated with a 33% lower risk for HAP (relative risk [RR], 0.67) and a 29% lower risk for ICU mortality (RR, 0.81). Reduction in pneumonia incidence was significant for patients receiving invasive mechanical ventilation (RR, 0.68) but not for patients who were not receiving invasive mechanical ventilation. Toothbrushing for patients in the ICU was associated with fewer days of mechanical ventilation (mean difference, −1.24 days) and a shorter ICU length of stay (mean difference, −1.78 days). Brushing twice a day vs more frequent intervals was associated with similar effect estimates. No differences were seen in duration of stay in various ICU subdepartments and in the use of antibiotics that were linked to daily toothbrushing. Expert Opinion: "This study represents an exciting contribution to infection prevention and reinforces the notion that routine toothbrushing is an essential component of standard of care in ventilated patients," wrote Rupak Datta, MD, PhD, assistant professor of infectious diseases at Yale University in New Haven, Connecticut, and specialist in antimicrobial resistance in hospital settings, in a commentary on the study. According to Datta, there is still uncertainty regarding the importance of this practice in preventing nonventilator-HAP, as the investigators could only identify two studies with nonventilated patients that met inclusion criteria. Other studies will be needed to help standardize toothbrushing in hospital patients admitted in general. "As the literature on HAP evolves," concluded Datta, "oral hygiene may take on an indispensable role, similar to hand washing, in preventing and controlling hospital-acquired infections."
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