Important knowledge
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GIANT-CELL TUMOUR
▪︎benign
▪︎Age: adult
▪︎Site : end of a long bone eccentrically
▪︎Mx : curettage & bone graft or cement
ANEURYSMAL BONE CYST
▪︎benign
▪︎Age : young adults
▪︎site : metaphysis ( trabeculated)
▪︎Mx: curettage & bone graft or cement (carefully )
SIMPLE BONE CYST
▪︎benign
▪︎Age : children
▪︎Site : metaphysis of long bones (common in proximal humerus & femur)
▪︎presentation : asymptomatic & rarely pathological fracture
▪︎Mx : follow up or
curettage & bone graft if enlrging or pathological fracture
OSTEOCHONDROMA (CARTILAGE-CAPPED EXOSTOSIS)
▪︎benign (with malignant potential )
▪︎site : metaphysis as exostosis (multiple if hereditary) of
1- fast-growing ends of
long bones
2- the crest of the ilium.
▪︎Mx :asymptomatic = follow up
Symptomatic = excision
CHONDROMYXOID FIBROMA
▪︎benign
▪︎Age : adolescents & young adults.
▪︎site :eccentrically in the metaphysis
▪︎Mx : curettage & bone graft
CHONDROBLASTOMA
▪︎benign
▪︎age : children
▪︎site : epiphysis ( proximal humerus, femur or tibia )
▪︎Mx : curettage & bone graft
ENCHONDROMA
▪︎benign ( low risk of Ca change)
▪︎Age: Adult
▪︎presentation : incidentally , pathological fracture
▪︎Site: junction of metaphysis
and diaphysis of metacarpals , metatarsals ,phalgess (hand&foot)
▪︎Mx : curettage & bone graft or cement
(only follow up for asymptomatic)
OSTEOBLASTOMA (GIANT OSTEOID OSTEOMA)
▪︎benign >1cm
▪︎presentation: as osteoid osteoma (night pain relive by aspirin)
▪︎site: spine & flat bones.
▪︎Mx :wide excision & bone grafting
OSTEOID OSTEOMA
▪︎ benign
▪︎Age : children & adolescent
▪︎ presentation: pain at night & relieved aspirin
▪︎ site : diaphysis / cortex of long bone
▪︎ Mx : marginal or wide excision
⚡️alkaline phosphatase (ALP) : enzyme of osteoblastic activity (high in some bone tumors)
⚡️The most common causative organisms of Acute osteomyelitis in pt.with sickle-cell anemia is ..Salmonella
⚡️The most common causative organisms of Acute osteomyelitis is staphylococcus aureus.
⚡️During infection & inflammation
▪︎ CRP rise after 6h & decrease after 2-3 day's
▪︎ ESR rise after 2-3 day's & decrease after 2-3 week's (up to 6) of resolution
