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Case-based MCQ

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Case-based MCQ (@casebasedmcq) Ingliz til segmentidagi kanali faol ishtirokchi. Hozirda hamjamiyat 19 278 obunachidan iborat bo'lib, Tibbiyot toifasida 1 203-o'rinni va Hindiston mintaqasida 22 958-o'rinni egallagan.

📊 Auditoriya ko‘rsatkichlari va dinamika

невідомо sanasidan buyon loyiha tez o‘sib, 19 278 obunachiga ega bo‘ldi.

13 Iyun, 2026 dagi oxirgi ma’lumotlarga ko‘ra kanal barqaror faollikka ega. Oxirgi 30 kunda obunachilar soni -195 ga, so‘nggi 24 soatda esa -6 ga o‘zgardi va umumiy qamrov yuqori darajada qolmoqda.

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  • Post qamrovi: Har bir post o‘rtacha 423 marta ko‘riladi; birinchi sutkada odatda 205 ta ko‘rish yig‘iladi.
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Enhance Your Medical Expertise with Case Based MCQ – Your Go-To Telegram Channel for Challenging, Real-World MCQs and Continuous Learning. Admin: @Mohamm_ADs

Yuqori yangilanish chastotasi (oxirgi ma’lumot 14 Iyun, 2026 da olingan) sababli kanal doimo dolzarb va katta qamrovli bo‘lib qoladi. Analitika auditoriya kontent bilan faol hamkorlik qilishini, uni Tibbiyot toifasidagi muhim ta’sir nuqtasiga aylantirishini ko‘rsatadi.

19 278
Obunachilar
-624 soatlar
-577 kunlar
-19530 kunlar
Postlar arxiv
A 7-year-old girl is brought to the emergency department due to a right arm injury. While jumping on a trampoline, she slippe
A 7-year-old girl is brought to the emergency department due to a right arm injury.  While jumping on a trampoline, she slipped and fell onto her outstretched right hand.  The patient had immediate pain and would not move her arm.  She did not hit her head or lose consciousness.  On examination, the patient is crying in pain, with significant ecchymosis and swelling just above the elbow.  She is holding the right arm in flexion and winces when it is moved.  X-ray reveals a supracondylar fracture with posterior displacement of the distal humerus fragment, as shown in the image below. Which of the following is at greatest risk of injury in this patient? A. Axillary artery B. Axillary nerve C. Brachial artery D. Brachial plexus E. Ulnar nerve

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Correct Answer Is B The risk factors for developing pseudogout include: -Age more than 70 years. -The family history of pseudogout. -Hypothyroidism. -Haemochromatosis. -Hyperparathyroidism. -Hypercalcemia.

Which of the following increases a person’s risk of getting pseudogout? A. Age less than 50 years B. Hypothyroidism C. Hypocalcaemia D. Hypoparathyroidisim E. Hypermagnesemia

Diagnosis of definitive SLE requires four or more criteria, with at least one clinical and one laboratory, with the exception of biopsy-proven LN (which requires fewer criteria). Criteria are cumulative and need not be present concurrently. The antinuclear antibodies (ANA) test is the serological hallmark of SLE. Up to 98% of patients with SLE will have a positive ANA, making it highly sensitive and useful as a screening test. A negative ANA makes SLE very unlikely and other diagnoses should be sought to explain symptoms. Antibodies to double-stranded DNA (dsDNA) are specific for SLE. In some patients, an increase in anti-dsDNA titre may signify onset of disease flare. Other autoantibodies, available on the extractable nuclear antigen-testing panel, can also be associated with SLE or other connective tissue diseases. Antibodies to Sm (anti-Smith), for example, has low sensitivity but high specificity for systemic lupus erythematosus (SLE). It is occasional present in mixed connective-tissue disease (MCTD) While antiphospholipid antibodies are not specific for SLE, they are part of the immunological abnormalities that can be associated with pregnancy morbidities and thrombotic complications. Testing should include anticardiolipin antibodies, lupus anticoagulant and anti-β2 glycoprotein 1.

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A 22-year-old lady presented to you with frequent fatigue, joint pain and weight loss. On physical examination noted that she has malar rash and oral ulcers. A diagnosis of systemic lupus erythematosus Which of the following statement is INCORRECT regarding SLE? A. It mainly affects women in high estrogen period B. It is more common in female C. Polyarthritis is the commonest symptom of SLE D. Antinuclear antibody is highly sensitive towards SLE E. Anti-Smith antibody is highly sensitive towards SLE

A 22-year-old lady presented to you with frequent fatigue, joint pain and weight loss. On physical examination noted that she has malar rash and oral ulcers. A diagnosis of systemic lupus erythematosus Which of the following statement is INCORRECT regarding SLE? A. It mainly affects women in high estrogen period B. It is more common in female C. Polyarthritis is the commonest symptom of SLE D. Antinuclear antibody is highly sensitive towards SLE E. Anti-Smith antibody is highly sensitive towards SLE

Correct Answer Is C This patient has presented with signs and symptoms of rheumatoid arthritis. The criteria to diagnose rheumatoid arthritis include the following: – Symptoms duration more than 6 weeks. – Early morning stiffness for more than 1 hour. – Arthritis in three or more joints. – Bilateral compression tenderness of the metatarsophalangeal joints. – Symmetry of the areas affected. – Rheumatoid factor, Anti-CCP antibody positivity. The role of non-steroidal anti-inflammatory drugs to reduce the pain and inflammation is well known in patients with rheumatoid arthritis. However, they do not prevent the joint damage and are associated with many side effects. Standard initial therapy with disease-modifying anti-rheumatic drugs helps to prevent damage to the joint in any patient with the rheumatoid arthritis. Methotrexate is the drug of choice as initial monotherapy. If disease remission is not achieved, increase the dose of methotrexate or consider combination therapy with other agents like sulfasalazine and hydroxychloroquine.

A 32-year-old woman presented with 3 month history of joint pain in both hands and stiffness lasting for hours once she wakes up in the morning every day. She also reported disturbed sleep due to the nocturnal pain. On examination, you notice swelling around metacarpophalangeal (MCP) and proximal interphalangeal (PIP) joint. Which ONE of the following is the drug of choice to reduce the synovial inflammation and prevent joint damage? A. Fish oil B. Naproxen C. Methotrexate D. Sulfasalazine E. Hydroxychloroquine

Correct Answer Is A She was diagnosed as systemic lupus erythematous (SLE) and treated with topical ointments, sunscreen lotion, oral prednisolone (for autoimmune hemolytic anemia) and hydroxychloroquine. Lupus (Latin for wolf) derives its name from the classical butterfly rash which mimics ‘the bite or scratch of a wolf’. Malar rash (butterfly rash), seen in 46–65% of lupus patients, is highly specific for the diagnosis of SLE. The rash may be raised or flat, scaly, non-pruritic and characteristically spares the nasolabial fold (differentiates from dermatomyositis). Common differential diagnoses include melasma (gray brown patches, common in pregnancy), dermatomyositis, lupus pernio and lupus vulgaris (indurated and nodular lesions), pellagra (symmetric keratotic areas on face which always affects body also), seborrheic dermatitis (also on other areas of face), rosacea (erythema, papule or pustules and telengiectasias on nose and medial cheeks, associated ocular features) and sunburn (significant pruritus and temporal association with sun exposure.

A 25-year-old married lady presented with increased hair loss, painless oral ulcers and rash over the face. She also had arthralgias involving small and large joints with early morning stiffness for 8 months. Physical examination revealed nonscarring alopecia, fixed erythematous maculopapular rash with hyperpigmen- tation over the cheeks and nasal bridge sparing nasolabial fold (Figure 1A). Multiple oral ulcers were also noted over the hard palate (Figure 1B). Investigations were notable for autoimmune hemolytic anemia (direct coombs test positive), leucopenia, anti- nuclear antibody positivity by indirect immunofluorescence method (dilution 1:160, 2þ intensity, pattern homogenous) and low complement (C3 and C4). Discuss and what is your diagnosis? Figure 1. (A) Maculopapular rash over the malar area in the shape of a butterfly, which is sparing the nasolabial folds (marked by black lines) and (B) multiple oral ulcers on the hard palate (black arrows). A. Systemic lupus erythematosus B. Pellagra C. Lupus Pernio D. Dermatomyositis E. Melasma

A
A

Correct Answer Is A The clinical picture of symmetrical swelling and tenderness of the metacarpophalangeal (MCP) and wrist joints lasting longer than 6 weeks strongly suggest rheumatoid arthritis. Rheumatoid factor, an immunoglobulin directed against the Fc portion of IgG, is positive in about two-thirds of cases and may be present early in the disease. The history of lethargy or fatigue is a common prodrome of RA. The inflammatory joint changes on examination are not consistent with chronic fatigue syndrome; furthermore, patients with CFS typically report fatigue existing for many years. The MCP-wrist distribution of joint symptoms makes osteoarthritis very unlikely. The x-ray changes described are characteristic of RA, but would occur later in the course of the disease. Although arthritis can occasionally be a manifestation of hematologic malignancies and, rarely, other malignancies, the only indicated screening would be a complete history and physical examination along with a CBC.

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A 40-year-old woman complains of 7 weeks of pain and swelling in both wrists and knees. She has several months of fatigue. After a period of rest, resistance to movement is more striking. On examination, the metacarpophalangeal joints and wrists are warm and tender. There are no other joint abnormalities. There is no alopecia, photosensitivity, kidney disease, or rash. Which of the following is correct? A. The clinical picture suggests early rheumatoid arthritis, and a rheumatoid factor should be obtained. B. The prodrome of lethargy suggests chronic fatigue syndrome. C. Lack of systemic symptoms suggests osteoarthritis. D. X-rays of the hand are likely to show joint space narrowing and erosion. E. An aggressive search for occult malignancy is indicated