MedPharm || طبصيدلة

Which medication is an immunotherapy targeting the programmed cell death protein 1 (PD-L1)? A) Atezolizumab B) Pembrolizumab C) Trastuzumab D) Pertuzumab E) Margetuximab

Which medication is an immunotherapy targeting the programmed cell death protein 1 (PD-1)? A) Atezolizumab B) Pembrolizumab C) Trastuzumab D) Pertuzumab E) Margetuximab

Which of the following drugs is a poly (ADP-ribose) polymerase (PARP) inhibitor? A) Letrozole B) Exemestane C) Olaparib D) Trastuzumab E) Pertuzumab

Which of the following is a phosphatidylinositol 3-kinase (PI3K) inhibitor used in patients with a PIK3CA mutation? A) Everolimus B) Alpelisib C) Olaparib D) Talazoparib E) Ribociclib

Which drug is a mammalian target of rapamycin (mTOR) inhibitor that improves progression-free survival? A) Everolimus B) Abemaciclib C) Palbociclib D) Neratinib E) Alpelisib

Which of the following is a monoclonal antibody targeted directly against the HER2 receptor protein? A) Pembrolizumab B) Atezolizumab C) Trastuzumab D) Bevacizumab E) Denosumab

—— is indicated for extended adjuvant therapy after the completion of trastuzumab. What is its mechanism of action? A) Alpelisib B) Fulvestrant C)Everolimus D)Pembrolizumab E) Neratinib

What is the primary therapeutic endpoint in the treatment of Metastatic Breast Cancer (MBC)? A) Eradication of all micro-metastases B) Cure of the disease C) Palliation D) Prevention of contralateral breast cancer E) Complete pathological response

Alpelisib is an approved targeted therapy for advanced or metastatic breast cancer in patients who have a mutation in which specific gene? A) BRCA1 B) BRCA2 C) PIK3CA D) TP53 E) ESR1

Which of the following is a monoclonal antibody targeted against the HER2 receptor protein used in patients with early-stage, HER2-positive breast cancer? A) Neratinib B) Trastuzumab C) Everolimus D) Alpelisib E) Pembrolizumab