MedPharm || طبصيدلة

R.S is 68 years old patient with history of Hypertension, MI, DM and depression who was stabilized on Mirtazapine due to its safety profile regarding patients with polypharmacy. recently he developed symptoms indicative of cognitive decline and memory issues. What treatment should you start for this patient?

Regarding antidepressants administration for the treatment of major depressive disorder, the following statements are true EXCEPT: a- Antidepressants are equal in efficacy when administered in comparable doses, and they are often classified by chemical structure and/or presumed mechanism b- The initial choice of antidepressant is often made empirically c- Older patients can be given the same initial dose given to younger adults d- At least a 6-week trial of an antidepressant at maximum dosage is considered an adequate trial of that medication e- An individual's pharmacogenomics may be useful when choosing therapy as a way to better predict antidepressant side effects or response

R.D is 44 years old man with negative past medical history, came to the psychiatry clinic complaining of diminished ability to experience pleasure, loss of interest in usual activities, sadness, pessimism, crying, hopelessness, anxiety, feelings of worthlessness. He also reported Weight gain, fatigue, headache, sleep disturbance, increased appetite, and loss of sexual interest. Given the likely diagnosis, what is the first line treatment option? a- Escitalopram b- Bupropion c- Imipramine d- Trazodone e- Mirtazapine

A 35-years ears old man suffering from Depression. After 8 weeks of sertraline therapy, the drug doesn't seem to be having a sufficient effect, but some symptoms of sexual dysfunction and insomnia. He would prefer to be prescribed a different class of antidepressant. What would you recommend next?