Dr. Ben Tapper

Journal editors are becoming increasingly aware of how they are being manipulated and are fighting back [17,18], but I must confess that it took me almost a quarter of a century editing for the BMJ to wake up to what was happening. Editors work by considering the studies submitted to them. They ask the authors to send them any related studies, but editors have no other mechanism to know what other unpublished studies exist. It’s hard even to know about related studies that are published, and it may be impossible to tell that studies are describing results from some of the same patients. Editors may thus be peer reviewing one piece of a gigantic and clever marketing jigsaw—and the piece they have is likely to be of high technical quality. It will probably pass peer review, a process that research has anyway shown to be an ineffective lottery prone to bias and abuse [19]. Furthermore, the editors are likely to favour randomised trials. Many journals publish few such trials and would like to publish more: they are, as I’ve said, a superior form of evidence. The trials are also likely to be clinically interesting. Other reasons for publishing are less worthy. Publishers know that pharmaceutical companies will often purchase thousands of dollars’ worth of reprints, and the profit margin on reprints is likely to be 70%. Editors, too, know that publishing such studies is highly profitable, and editors are increasingly responsible for the budgets of their journals and for producing a profit for the owners. Many owners—including academic societies—depend on profits from their journals. An editor may thus face a frighteningly stark conflict of interest: publish a trial that will bring US$100 000 of profit or meet the end-of-year budget by firing an editor. Journals Should Critique Trials, Not Publish Them How might we prevent journals from being an extension of the marketing arm of pharmaceutical companies in publishing trials that favour their products? Editors can review protocols, insist on trials being registered, demand that the role of sponsors be made transparent, and decline to publish trials unless researchers control the decision to publish [17,18]. I doubt, however, that these steps will make much difference. Something more fundamental is needed. Firstly, we need more public funding of trials, particularly of large head-to-head trials of all the treatments available for treating a condition. Secondly, journals should perhaps stop publishing trials. Instead, the protocols and results should be made available on regulated Web sites. Only such a radical step, I think, will stop journals from being beholden to companies. Instead of publishing trials, journals could concentrate on critically describing them. Examples of Methods for Pharmaceutical Companies to Get the Results They Want from Clinical Trials Conduct a trial of your drug against a treatment known to be inferior. Trial your drugs against too low a dose of a competitor drug. Conduct a trial of your drug against too high a dose of a competitor drug (making your drug seem less toxic). Conduct trials that are too small to show differences from competitor drugs. Use multiple endpoints in the trial and select for publication those that give favourable results. Do multicentre trials and select for publication results from centres that are favourable. Conduct subgroup analyses and select for publication those that are favourable. Present results that are most likely to impress—for example, reduction in relative rather than absolute risk” http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0020138 Failure of the excretory system influences elimination of heavy metals and facilitates their accumulation and subsequent manifestation as neurotoxins: the long-term consequences of which would lead to neurodegeneration, cognitive and developmental problems. It may also influence regulation of neural hyperthermia.

Fortunately from the point of view of the companies funding these trials—but unfortunately for the credibility of the journals who publish them—these trials rarely produce results that are unfavourable to the companies’ products [7,8]. Paula Rochon and others examined in 1994 all the trials funded by manufacturers of nonsteroidal anti-inflammatory drugs for arthritis that they could find [7]. They found 56 trials, and not one of the published trials presented results that were unfavourable to the company that sponsored the trial. Every trial showed the company’s drug to be as good as or better than the comparison treatment. By 2003 it was possible to do a systematic review of 30 studies comparing the outcomes of studies funded by the pharmaceutical industry with those of studies funded from other sources [8]. Some 16 of the studies looked at clinical trials or meta-analyses, and 13 had outcomes favourable to the sponsoring companies. Overall, studies funded by a company were four times more likely to have results favourable to the company than studies funded from other sources. In the case of the five studies that looked at economic evaluations, the results were favourable to the sponsoring company in every case. The evidence is strong that companies are getting the results they want, and this is especially worrisome because between two-thirds and three-quarters of the trials published in the major journals—Annals of Internal Medicine, JAMA, Lancet, and New England Journal of Medicine—are funded by the industry [9]. For the BMJ, it’s only one-third—partly, perhaps, because the journal has less influence than the others in North America, which is responsible for half of all the revenue of drug companies, and partly because the journal publishes more cluster-randomised trials (which are usually not drug trials) [9]. Why Do Pharmaceutical Companies Get the Results They Want? Why are pharmaceutical companies getting the results they want? Why are the peer-review systems of journals not noticing what seem to be biased results? The systematic review of 2003 looked at the technical quality of the studies funded by the industry and found that it was as good—and often better—than that of studies funded by others [8]. This is not surprising as the companies have huge resources and are very familiar with conducting trials to the highest standards. The companies seem to get the results they want not by fiddling the results, which would be far too crude and possibly detectable by peer review, but rather by asking the “right” questions—and there are many ways to do this [10]. Some of the methods for achieving favourable results are listed in the Sidebar, but there are many ways to hugely increase the chance of producing favourable results, and there are many hired guns who will think up new ways and stay one jump ahead of peer reviewers. Then, various publishing strategies are available to ensure maximum exposure of positive results. Companies have resorted to trying to suppress negative studies [11,12], but this is a crude strategy—and one that should rarely be necessary if the company is asking the “right” questions. A much better strategy is to publish positive results more than once, often in supplements to journals, which are highly profitable to the publishers and shown to be of dubious quality [13,14]. Companies will usually conduct multicentre trials, and there is huge scope for publishing different results from different centres at different times in different journals. It’s also possible to combine the results from different centres in multiple combinations. These strategies have been exposed in the cases of risperidone [15] and odansetron [16], but it’s a huge amount of work to discover how many trials are truly independent and how many are simply the same results being published more than once. And usually it’s impossible to tell from the published studies: it’s necessary to go back to the authors and get data on individual patients. Peer Review Doesn’t Solve the Problem

aluminum in vaccines is safe appears to be widely accepted. Experimental research, however, clearly shows that aluminum adjuvants have a potential to induce serious immunological disorders in humans. In particular, aluminum in adjuvant form carries a risk for autoimmunity, long-term brain inflammation and associated neurological complications and may thus have profound and widespread adverse health consequences. In our opinion, the possibility that vaccine benefits may have been overrated and the risk of potential adverse effects underestimated, has not been rigorously evaluated in the medical and scientific community. We hope that the present paper will provide a framework for a much needed and long overdue assessment of this highly contentious medical issue. http://www.meerwetenoverfreek.nl/images/stories/Tomljenovic_Shaw-CMC-published.pdf High reprint orders in medical journals and pharmaceutical industry funding: case-control study http://www.bmj.com/content/344/bmj.e4212 about the author: ”  RS was an editor for the BMJ for 25 years. For the last 13 of those years, he was the editor and chief executive of the BMJ Publishing Group, responsible for the profits of not only the BMJ but of the whole group, which published some 25 other journals. He stepped down in July 2004. He is now a member of the board of the Public Library of Science, a position for which he is not paid.” “Journals have devolved into information laundering operations for the pharmaceutical industry”, wrote Richard Horton, editor of the Lancet, in March 2004 [1]. In the same year, Marcia Angell, former editor of the New England Journal of Medicine, lambasted the industry for becoming “primarily a marketing machine” and co-opting “every institution that might stand in its way” [2]. Medical journals were conspicuously absent from her list of co-opted institutions, but she and Horton are not the only editors who have become increasingly queasy about the power and influence of the industry. Jerry Kassirer, another former editor of the New England Journal of Medicine, argues that the industry has deflected the moral compasses of many physicians [3], and the editors of PLoS Medicine have declared that they will not become “part of the cycle of dependency…between journals and the pharmaceutical industry” [4]. Something is clearly up. The Problem: Less to Do with Advertising, More to Do with Sponsored Trials The most conspicuous example of medical journals’ dependence on the pharmaceutical industry is the substantial income from advertising, but this is, I suggest, the least corrupting form of dependence. The advertisements may often be misleading [5,6] and the profits worth millions, but the advertisements are there for all to see and criticise. Doctors may not be as uninfluenced by the advertisements as they would like to believe, but in every sphere, the public is used to discounting the claims of advertisers. The much bigger problem lies with the original studies, particularly the clinical trials, published by journals. Far from discounting these, readers see randomised controlled trials as one of the highest forms of evidence. A large trial published in a major journal has the journal’s stamp of approval (unlike the advertising), will be distributed around the world, and may well receive global media coverage, particularly if promoted simultaneously by press releases from both the journal and the expensive public-relations firm hired by the pharmaceutical company that sponsored the trial. For a drug company, a favourable trial is worth thousands of pages of advertising, which is why a company will sometimes spend upwards of a million dollars on reprints of the trial for worldwide distribution. The doctors receiving the reprints may not read them, but they will be impressed by the name of the journal from which they come. The quality of the journal will bless the quality of the drug.

Prior to the introduction of vaccines, children who were absent at a village examination had the same mortality as children who were present. During 1984-1987, children receiving DTP at 2-8 months of age had higher mortality over the next 6 months, the mortality rate ratio (MR) being 1.92 (95% CI: 1.04, 3.52) compared with DTP-unvaccinated children, adjusting for age, sex, season, period, BCG, and region. The MR was 1.81 (95% CI: 0.95, 3.45) for the first dose of DTP and 4.36 (95% CI: 1.28, 14.9) for the second and third dose. BCG was associated with slightly lower mortality (MR = 0.63, 95% CI: 0.30, 1.33), the MR for DTP and BCG being significantly inversed. Following subsequent visits and further vaccinations with DTP and measles vaccine, there was no difference in vaccination coverage and subsequent mortality between the DTP-vaccinated group and the initially DTP-unvaccinated group (MR = 1.06, 95% CI: 0.78, 1.44). CONCLUSIONS: In low-income countries with high mortality, DTP as the last vaccine received may be associated with slightly increased mortality. Since the pattern was inversed for BCG, the effect is unlikely to be due to higher-risk children having received vaccination. The role of DTP in high mortality areas needs to be clarified. http://www.ncbi.nlm.nih.gov/pubmed/15082643 Aluminium is the most widely distributed metal in the environment and is extensively used in daily life that provides easy exposure to human beings. The exposure to this toxic metal occurs through air, food and water. However, there is no known physiological role for aluminium within the body and hence this metal may produce adverse physiological effects. Chronic exposure of animals to aluminium is associated with behavioural, neuropathological and neurochemical changes. Among them, deficits of learning and behavioural functions are most evident. Some epidemiological studies have shown poor performance in cognitive tests and a higher abundance of neurological symptoms for workers occupationally exposed to aluminium. http://www.ncbi.nlm.nih.gov/pubmed/19568732 High blood mercury level was associated with ADHD. Whether the relationship is causal requires further studies. http://www.ncbi.nlm.nih.gov/pubmed/?term=17177150 conflicts of interest? Wow..this is from a study that concluded that boys need the HPV vaccine..a vaccine for cervical cancer. You can find this info at the bottom of the article. “Supported by Merck and by grants (M01-RR-00079 and UL1 RR024131, to Dr. Palefsky) from the National Center for Research Resources and by a grant (RO1 CA098803, to Dr. Giuliano) from the National Institutes of Health. Drs. Giuliano, Ferris, Moreira, Penny, and Palefsky report receiving grant support from Merck, either personally or through their institution; Dr. Penny reports receiving grant support from GlaxoSmithKline; Dr. Goldstone reports receiving grant support from Qiagen; Drs. Giuliano, Ferris, Moreira, Hillman, and Chang report receiving speaking fees or fees for board membership from Merck; Dr. Moi reports that his institution has received funding from Merck; Dr. Penny reports having stock or stock options in AstraZeneca; Dr. Palefsky reports receiving consulting fees from GlaxoSmithKline; Drs. Giuliano, Palefsky, Goldstone, Moreira, Moi, and Chang report receiving travel reimbursement from Merck; Dr. Bryan reports having an approved, filed, or pending patent related to subject matter discussed in this article; and Dr. Bryan, Dr. Marshall, Dr. Vuocolo, Dr. Barr, Dr. Haupt, Mr. Radley, and Dr. Guris are employees of Merck and own Merck stock or stock options.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495065/ Abstract: Aluminum is an experimentally demonstrated neurotoxin and the most commonly used vaccine adjuvant. Despite almost 90 years of widespread use of aluminum adjuvants, medical science’s understanding about their mechanisms of action is still remarkably poor. There is also a concerning scarcity of data on toxicology and pharmacokinetics of these compounds. In spite of this, the notion that

Aluminum can cross the blood-brain barrier and accumulate in glial and neural cells [15]. Thus, high intake of Al-containing formula might cause accumulation of Al in the neonatal brain, interfering with appropriate development. In previous studies, exposure to excess dietary Al during gestation and lactation periods had no toxic effects on the mother, but resulted in persistent neurobehavioral deficits in the pups, such as defects in the sensory motor reflexes, locomotor activity, learning capability, and cognitive behavior [16,17]. These behavioral studies, therefore, suggested that Al exposure might cause developmental changes in neonatal brain. Until recently, a marker with which to effectively detect neonatal brain development was lacking. The group’s previous study with Al treatment in neonatal rat hippocampal neurons at concentrations of 37 μM and 74 μM for 14 days significantly reduced NMDAR (N-methyl-D-aspartate receptor) expression which was used as a marker of brain development. This suggested that Al exposure might influence the development of hippocampal neurons in neonatal rats. http://www.jbiomedsci.com/content/19/1/51 The future of measles in highly immunized population. A modeling approach However, despite short-term success in eliminating the disease, long-range projections demonstrate that the proportion of susceptibles in the year 2050 may be greater than in the prevaccine era. Present vaccine technology and public health policy must be altered to deal with this eventuality. http://www.ncbi.nlm.nih.gov/pubmed/6741921 Summary In conclusion, by apparently prioritizing vaccination policy over vaccine safety, the JCVI, the DH and the Committee on Safety of Medicines (CSM) may have shown a disregard for the safety of children. Through selective data reporting, the JCVI in conjunction with the DH, has promulgated information relating to vaccine safety that may be inaccurate and potentially misleading, thereby making it impossible for the parents to make a fully informed consent regarding vaccination. Furthermore, by 1) apparently misleading patients about the true risks of adverse reactions as to gain their consent for the administration of the treatment and 2) seemingly siding with vaccine manufacturers rather than public health interests, the JCVI and the CSM appear to have signally failed their fiduciary duty to protect individuals from vaccines of questionable safety. If these provisional conclusions are indeed correct, then the information presented here may help us in understanding the UK government’s and the JCVI’s official position on vaccine damage, that is, one of persistent denial. http://www.ecomed.org.uk/wp-content/uploads/2011/09/3-tomljenovic.pdf “One way forward that appears to be favoured by most in the medical establishment is to continue to add more and more vaccines indiscriminately to the immunisation schedule in ever larger combinations. Just to question this policy is to be accused of putting children’s lives at risk and of being “anti-vaccine”. I have been called “anti-vaccine” even though I actually run a children’s immunisation clinic! The government can;t bear any suggestion of lack of safety of vaccines. They will not even discuss it. I think they have a policy of suppression of any discussion on safety. This was said by a leading vaccine expert with the Cochrane Collaboration, a widely respected international not-for-profit and independent organisation, dedicated to making up-to-date and accurate information about the effects of health care readily available worldwide. I would advocate another way forward: a more cautious approach incorporating honesty about the true benefits and risks of vaccination to enable parents to make a genuinely informed choice. I would like to see an environment in which parents are able to have a rational discussion without bullying, patronising, condescension and being accused of putting their child at risk.” “Vaccine, Atopy and Allergy: Problems and Solutions” http://www.ecomed.org.uk/wp-content/uploads/2011/09/2-halvorsen.pdf

This protein band, as analyzed with monoclonal anti bodies, was immunopositive for measles hemagglutinin (HA) protein but not for measles nucleoprotein and rubella or mumps viral proteins. Thus the MMR antibody in autistic sera detected measles HA protein, which is unique to the measles subunit of the vaccine. Furthermore, over 90% of MMR antibody-positive autistic sera were also positive for MBP autoantibodies, suggesting a strong association between MMR and CNS autoimmunity in autism. Stemming from this evidence, we suggest that an inappropriate antibody response to MMR, specifically the measles component thereof, might be related to pathogenesis of autism.” http://www.ncbi.nlm.nih.gov/pubmed/12145534 http://vran.org/wp-content/documents/VRAN-Abnormal%20Measles-Mumps-Rubella-Antibodies-CNS-Autoimmunity-Children-Autism-Singh-Lin-Newell-Nelson.pdf “Autoimmune hazards of hepatitis B vaccine” “According to Hippocratic tradition, the safety level of a preventive medicine must be very high, as it is aimed at protecting people against diseases that they may not contract. This paper points out that information on the safety of hepatitis B vaccine (HBV) is biased as compared to classical requirements of evidence-based medicine (EBM), as exemplified by a documented selectivity in the presentation or even publication of available clinical or epidemiological data. Then, a review is made of data suggesting that HBV is remarkable by the frequency, the severity and the variety of its complications, some of them probably related to a mechanism of molecular mimicry leading to demyelinating diseases, and the others reproducing the spectrum of non-hepatic manifestations of natural hepatitis B. To be explained, this unusual spectrum of toxicity requires additional investigations based upon complete release of available data. -More research is necessary and there is a need that the scientific community exerts pressure on health authorities to obtain that all existing data become available for peer-reviewed debate. -There is an impressive convergence of data given credibility to a potential of this vaccine to induce severe and irreversible central demyelinating disorders. -A number of clinical or epidemiological data on the safety hepatitis B vaccine (HBV) have not been published and do not seem to be. -Modern vaccine research and development does not comply with basic requirements of evidence based medicine (EBM).” http://www.ncbi.nlm.nih.gov/pubmed/15722255 FULL TEXT http://sanevax.org/wp-content/uploads/2011/02/autoimmune-hazards-hepB-vaccine1.pdf “We find that ethylmercury not only inhibits mitochondrial respiration leading to a drop in the steady state membrane potential, but also concurrent with these phenomena increases the formation of superoxide, hydrogen peroxide, and Fenton/Haber-Weiss generated hydroxyl radical. These oxidants increase the levels of cellular aldehyde/ketones. Additionally, we find a five-fold increase in the levels of oxidant damaged mitochondrial DNA bases and increases in the levels of mtDNA nicks and blunt-ended breaks.. These mitochondria appear to have undergone a permeability transition, an observation supported by the five-fold increase in Caspase-3 activity observed after Thimerosal treatment.” *the next time someone says that ethylmercury is ok for children ask them to read this article. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395253/ The main route of Al excretion is the urine; therefore, subjects with kidney malfunction or immature kidney, such as nephropathy patients or neonates, might experience toxic accumulation of Al in the body [12]. Infant formula is the primary food source for bottle-fed neonates. The study of Yuan et al reviewed several other studies and reported that most commercial infant formulas contained higher Al (6.5 μM to 87 μM) than human breast milk (0.2 μM to 1.7 μM) [12]. Infants display rapid growth and their brain-blood-barrier, detoxification system (liver), and excretory system (kidney) are not well-developed [13,14].

Thus autistic children have a hyperimmune response to measles virus, which in the absence of a wild type of measles infection might be a sign of an abnormal immune reaction to the vaccine strain or virus reactivation.” http://www.ncbi.nlm.nih.gov/pubmed/12849883 We do not vaccinate against yellow fever in the US but this still is of importance because it shows that things like this can and HAVE happened. “However, in 2001, the vaccine was found to cause a serious, frequently fatal, multisystemic illness, called yellow fever vaccine–associated viscerotropic disease (YEL-AVD), which resembles the illness it was designed to prevent (1–3). ” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3310656/ Effectiveness of Influenza Vaccine in the Community-Dwelling Elderly “Most high-risk medical conditions that were measured were more prevalent among vaccinated than among unvaccinated persons.” http://jama.jamanetwork.com/article.aspx?articleid=189023 ” The aim of this study was to compare the number of inactivated-influenza vaccine–related spontaneous abortion and stillbirth (SB) reports in the Vaccine Adverse Event Reporting System (VAERS) database during three consecutive flu seasons beginning 2008/2009 and assess the relative fetal death reports associated with the two-vaccine 2009/2010 season. The VAERS database was searched for reports of fetal demise following administration of the influenza vaccine/vaccines to pregnant women.. reporting bias was too low to explain the magnitude increase in fetal-demise reporting rates in the VAERS database relative to the reported annual trends. Thus, a synergistic fetal toxicity likely resulted from the administration of both the pandemic (A-H1N1) and seasonal influenza vaccines during the 2009/2010 season.” http://het.sagepub.com/content/early/2012/09/12/0960327112455067.abstract Hepatitis B vaccine might be followed by various rheumatic conditions and might trigger the onset of underlying inflammatory or autoimmune rheumatic diseases.. Further epidemiological studies are needed to establish whether hepatitis B vaccination is associated or not with an incidence of rheumatic disorders higher than normal. A few cases of onset or reactivation of SLE after vaccination against hepatitis B have been described. The onset of symptoms occurred within 5 days–1 month after the immunization. Two patients had a lupus nephritis (associated in one with fever and arthralgia), one patient had pericarditis, one had thrombocytopenic purpura.. We observed four patients with myalgia and polyarthralgia, and, in three of them, fatigue following hepatitis B vaccination. These manifestations can be connected to the chronic fatigue syndrome. A few years ago, an independent working group agreed that there was no evidence of a cause–effect relationship between hepatitis B vaccine and chronic fatigue syndrome [37]. However, the number of patients followed up may have been too small to detect a slight increase in the relative risk. Various other conditions following hepatitis B vaccination have been described. They include erythema nodosum and polyarthritis [21], erythema nodosum with arthralgia and Takayasu’s arteritis [38], vasculitis [39–41], polyarthritis associated with hypercalcaemia and lytic bone lesions [29]. http://rheumatology.oxfordjournals.org/content/38/10/978.long “Autoimmunity to the central nervous system (CNS), especially to myelin basic protein (MBP), may play a causal role in autism, a neurodevelopmental disorder. Because many autistic children harbor elevated levels of measles antibodies, we conducted a serological study of measles-mumps-rubella (MMR) and MBP autoantibodies. Using serum samples of 125 autistic children and 92 control children, antibodies were assayed by ELISA or immunoblotting methods. ELISA analysis showed a significant increase in the level of MMR antibodies in autistic children. Immunoblotting analysis revealed the presence of an unusual MMR antibody in 75 of 125 (60%) autistic sera but not in control sera. This antibody specifically detected a protein of 73-75 kD of MMR.

vaccination led to a 40-fold enhancement of B. parapertussis colonization in the lungs of mice.. these data suggest that the vaccine may be contributing to the observed rise in whooping cough incidence over the last decade by promoting B. parapertussis infection.” http://www.cidd.psu.edu/research/synopses/acellular-vaccine-enhancement-b.-parapertussis Despite widespread childhood vaccination against Bordetella pertussis, disease remains prevalent. It has been suggested that acellular vaccine may be less effective than previously believed. During a large outbreak, we examined the incidence of pertussis and effectiveness of vaccination in a well-vaccinated, well-defined community.. Our data suggests that the current schedule of acellular pertussis vaccine doses is insufficient to prevent outbreaks of pertussis. http://cid.oxfordjournals.org/content/early/2012/03/13/cid.cis287.short In the last 3 decades, there has been an unexplained increase in the prevalence of asthma and hay fever. OBJECTIVE: We sought to determine whether there is an association between childhood vaccination and atopic diseases, and we assessed the self-reported prevalence of atopic diseases in a population that included a large number of families not vaccinating their children. RESULTS: The data included 515 never vaccinated, 423 partially vaccinated, and 239 completely vaccinated children. In multiple regression analyses there were significant ( P < .0005) and dose-dependent negative relationships between vaccination refusal and self-reported asthma or hay fever only in children with no family history of the condition and, for asthma, in children with no exposure to antibiotics during infancy. Vaccination refusal was also significantly ( P < .005) and negatively associated with self-reported eczema and current wheeze. A sensitivity analysis indicated that substantial biases would be required to overturn the observed associations. CONCLUSION: Parents who refuse vaccinations reported less asthma and allergies in their unvaccinated children. Although this relationship was independent of measured confounders, it could be due to differences in other unmeasured lifestyle factors or systematic bias. Further research is needed to verify these results and investigate which exposures are driving the associations between vaccination refusal and allergic disease.. http://www.ncbi.nlm.nih.gov/pubmed/15805992 “Unvaccinated children tended to be white, to have a mother who was married and had a college degree, to live in a household with an annual income exceeding $75,000 dollars, and to have parents who expressed concerns regarding the safety of vaccines and indicated that medical doctors have little influence over vaccination decisions for their children.” http://www.ncbi.nlm.nih.gov/pubmed/15231927 Although persons often use vaccination and immunization interchangeably in reference to active immunization, the terms are not synonomous because the administration of an immunobiologic cannot be automatically equated with the development of adequate immunity. http://wonder.cdc.gov/wonder/prevguid/p0000348/p0000348.asp#head002000000000000 “Virus-induced autoimmunity may play a causal role in autism. To examine the etiologic link of viruses in this brain disorder, we conducted a serologic study of measles virus, mumps virus, and rubella virus. Viral antibodies were measured by enzyme-linked immunosorbent assay in the serum of autistic children, normal children, and siblings of autistic children. The level of measles antibody, but not mumps or rubella antibodies, was significantly higher in autistic children as compared with normal children (P = 0.003) or siblings of autistic children (P <or= 0.0001). Furthermore, immunoblotting of measles vaccine virus revealed that the antibody was directed against a protein of approximately 74 kd molecular weight. The antibody to this antigen was found in 83% of autistic children but not in normal children or siblings of autistic children.

Ten to 12 days post 18 month vaccination, the relative incidence was 1.25 (95%, 1.17–1.33) which represented at least one excess event for every 730 children vaccinated. The primary reason for increased events was statistically significant elevations in emergency room visits following all vaccinations. There were non-significant increases in hospital admissions. There were an additional 20 febrile seizures for every 100,000 vaccinated at 12 months. Conclusions There are significantly elevated risks of primarily emergency room visits approximately one to two weeks following 12 and 18 month vaccination. Future studies should examine whether these events could be predicted or prevented http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236196/ “Administration of thimerosal to infant rats increases overflow of glutamate and aspartate in the prefrontal cortex: protective role of dehydroepiandrosterone sulfate.  “ In summary, the present study documents that exposure of infant rats to THIM perturbs the balance between excitatory and inhibitory amino acids in the brain, shifting it toward excessive neuroexcitation. Despite of intrinsic limitations, present findings have important clinical implications, as they provide a plausible mechanism, whereby THIM exerts neurotoxic effects in the brain. It is likely that this mercurial—still present in pediatric vaccines in many countries—causes a similar disturbance of excitatory and inhibitory neurotransmitters in the brains of human infants, leading to neurotoxicity, encephalopaties, and in consequence to neurodevelopmental disorders, including autism..*On the whole, the current study provides further empirical evidence that exposure to THIM leads to neurotoxic changes in the developing brain, arguing for urgent and permanent removal of this preservative from all vaccines for children (and adults) since effective, less toxic and less costly alternatives are available. The stubborn insistence of some vaccine manufacturers and health agencies on continuation of use of this proven neurotoxin in vaccines is testimony of their disregard for both the health of young generations and for the environment.* http://www.ncbi.nlm.nih.gov/pubmed/22015977 “Thus vaccination DOES NOT account for the impressive declines in mortality seen in the first half of the century” http://pediatrics.aappublications.org/content/106/6/1307.abstract Thimerosal, an organomercurial added as a preservative to some vaccines, is a suspected iatrogenic factor, possibly contributing to paediatric neurodevelopmental disorders including autism. We examined the effects of early postnatal administration of thimerosal (four i.m. injections, 12 or 240 μg THIM-Hg/kg, on postnatal days 7, 9, 11 and 15) on brain pathology in Wistar rats. Numerous neuropathological changes were observed in young adult rats which were treated postnatally with thimerosal. They included: ischaemic degeneration of neurons and “dark” neurons in the prefrontal and temporal cortex, the hippocampus and the cerebellum, pathological changes of the blood vessels in the temporal cortex, diminished synaptophysin reaction in the hippocampus, atrophy of astroglia in the hippocampus and cerebellum, and positive caspase-3 reaction in Bergmann astroglia. These findings document neurotoxic effects of thimerosal, at doses equivalent to those used in infant vaccines or higher, in developing rat brain, suggesting likely involvement of this mercurial in neurodevelopmental disorders. http://www.ncbi.nlm.nih.gov/pubmed/21225508 and it’s the unvaccinated that are spreading pertussis? “Despite widespread vaccination, whooping cough incidence is on the rise worldwide, making it the only vaccine-preventable disease associated with increasing deaths in the United States. Although this disease is most often attributed to Bordetella pertussis infection, it is also caused by the closely related pathogen, B. parapertussis. However, B. pertussis has remained the center of attention, whereas B. parapertussis has been greatly overlooked in the development of whooping cough vaccines.

“Furthermore, while India has been polio-free for a year, there has been a huge increase in non-polio acute flaccid paralysis (NPAFP). In 2011, there were an extra 47,500 new cases of NPAFP. Clinically indistinguishable from polio paralysis but twice as deadly, the incidence of NPAFP was directly proportional to doses of oral polio received. Though this data was collected within the polio surveillance system, it was not investigated.” http://www.ncbi.nlm.nih.gov/pubmed/22591873 Detection of fecal shedding of rotavirus vaccine in infants following their first dose of pentavalent rotavirus vaccine. (and how they blame everything on kids that are not vaccinated is beyond me! These vaccines are helping to keep diseases in circulation..) Studies on rotavirus vaccine shedding and its potential transmission within households including immunocompromised individuals are needed to better define the potential risks and benefits of vaccination. We examined fecal shedding of pentavalent rotavirus vaccine (RV5) for 9 days following the first dose of vaccine in infants between 6 and 12 weeks of age. Rotavirus antigen was detected by enzyme immunoassay (EIA), and vaccine-type rotavirus was identified by nucleotide sequencing based on genetic relatedness to the RV5 VP6 gene. Stool from 22 (21.4%) of 103 children contained rotavirus antigen-positive specimens on ≥ 1 post-vaccination days. Rotavirus antigen was detected as early as post-vaccination day 3 and as late as day 9, with peak numbers of shedding on post-vaccination days 6 through 8. Vaccine-type rotavirus was detected in all 50 antigen-positive specimens and 8 of 8 antigen-negative specimens. Nine (75%) of 12 EIA-positive and 1 EIA-negative samples tested culture-positive for vaccine-type rotavirus. Fecal shedding of rotavirus vaccine virus after the first dose of RV5 occurred over a wide range of post-vaccination days not previously studied. These findings will help better define the potential for horizontal transmission of vaccine virus among immunocompromised household contacts of vaccinated infants for future studies http://www.ncbi.nlm.nih.gov/pubmed/21477676 “Effectiveness of trivalent inactivated influenza vaccine in influenza-related hospitalization in children: a case-control study.” “Using the Cochran-Mantel-Haenszel test for asthma status stratification, there was a significant association between hospitalization in asthmatic subjects and TIV (p = 0.001). TIV did not provide any protection against hospitalization in pediatric subjects, especially children with asthma. On the contrary, we found a threefold increased risk of hospitalization in subjects who did get the TIV vaccine. This may be a reflection not only of vaccine effectiveness but also the population of children who are more likely to get the vaccine.” http://www.ncbi.nlm.nih.gov/pubmed/22525386 The odds of having a history of asthma was twice as great among vaccinated subjects than among unvaccinated subjects (adjusted odds ratio, 2.00; 95% confidence interval, 0.59 to 6.74). The odds of having had any allergy-related respiratory symptom in the past 12 months was 63% greater among vaccinated subjects than unvaccinated subjects (adjusted odds ratio, 1.63; 95% confidence interval, 1.05 to 2.54). The associations between vaccination and subsequent allergies and symptoms were greatest among children aged 5 through 10 years. DTP or tetanus vaccination appears to increase the risk of allergies and related respiratory symptoms in children and adolescents. Although it is unlikely that these results are entirely because of any sources of bias, the small number of unvaccinated subjects and the study design limit our ability to make firm causal inferences about the true magnitude of effect. http://www.ncbi.nlm.nih.gov/pubmed/10714532 Four to 12 days post 12 month vaccination, children had a 1.33 (1.29–1.38) increased relative incidence of the combined endpoint compared to the control period, or at least one event during the risk interval for every 168 children vaccinated.

”4 Administering six, seven, or eight vaccine doses to an infant during a single physician visit may certainly be more convenient for parents—rather than making additional trips to the doctor’s office—but evidence of a positive association between infant adverse reactions and the number of vaccine doses administered confirms that vaccine safety must remain the highest priority” http://het.sagepub.com/content/31/10/1012.full “Maternal transfer of mercury to the developing embryo/fetus: is there a safe level?” “This study focused on standardized embryonic and fetal Hg exposures via primary exposure to the pregnant mother of two common Hg sources (dietary fish and parenteral vaccines). Data demonstrated that Hg exposures, particularly during the first trimester of pregnancy, at well-established dose/weight ratios produced severe damage to humans including death. . In light of research suggestive of a mercuric risk factor for childhood conditions such as tic disorders, cerebral palsy, and autism, it is essential that Hg advisories account for secondary prenatal human exposures.” http://www.tandfonline.com/doi/full/10.1080/02772248.2012.724574 Empirical Data Confirm Autism Symptoms Related to Aluminum and Acetaminophen Exposure “Autism is a condition characterized by impaired cognitive and social skills, associated with compromised immune function. The incidence is alarmingly on the rise, and environmental factors are increasingly suspected to play a role. This paper investigates word frequency patterns in the U.S. CDC Vaccine Adverse Events Reporting System (VAERS) database. Our results provide strong evidence supporting a link between autism and the aluminum in vaccines. A literature review showing toxicity of aluminum in human physiology offers further support. Mentions of autism in VAERS increased steadily at the end of the last century, during a period when mercury was being phased out, while aluminum adjuvant burden was being increased. Using standard log-likelihood ratio techniques, we identify several signs and symptoms that are significantly more prevalent in vaccine reports after 2000, including cellulitis, seizure, depression, fatigue, pain and death, which are also significantly associated with aluminum-containing vaccines. We propose that children with the autism diagnosis are especially vulnerable to toxic metals such as aluminum and mercury due to insufficient serum sulfate and glutathione. A strong correlation between autism and the MMR (Measles, Mumps, Rubella) vaccine is also observed, which may be partially explained via an increased sensitivity to acetaminophen administered to control fever.” http://www.mdpi.com/1099-4300/14/11/2227 full text: http://groups.csail.mit.edu/sls/publications/2012/entropy-14-02227.pdf Acetaminophen use after measles-mumps-rubella vaccination was SIGNIFICANTLY associated with autistic disorder when considering children 5 years of age or less, after limiting cases to children with regression in development and when considering only children who had post-vaccination sequelae adjusting for age, gender, mother’s ethnicity, and the presence of illness concurrent with measles-mumps-rubella vaccination. Ibuprofen use after measles-mumps-rubella vaccination was not associated with autistic disorder. This preliminary study found that acetaminophen use after measles-mumps-rubella vaccination was associated with autistic disorder. http://www.ncbi.nlm.nih.gov/pubmed/18445737 A 1% increase in vaccination was associated with an additional 680 children having AUT or SLI. Neither parental behavior nor access to care affected the results, since vaccination proportions were not significantly related (statistically) to any other disability or to the number of pediatricians in a U.S. state. The results suggest that although mercury has been removed from many vaccines, other culprits may link vaccines to autism. Further study into the relationship between vaccines and autism is warranted” http://www.ncbi.nlm.nih.gov/pubmed/21623535

Allison and Steven Council on behalf of Adam Council, Plainfield, Illinois, Court of Federal Claims No: 13-0276V. 41. Maryann Giordano, Lindenhurst, New York, Court of Federal Claims No: 13-0277V. 42. Laura A. Jones, Greensboro, North Carolina, Court of Federal Claims No: 13-0279V. 43. David D. Griffin, Afghanistan, Court of Federal Claims No: 13-0280V. 44. James Demoski, Endicott, New York, Court of Federal Claims No: 13-0286V. 45. Christina N. Steinat, Seattle, Washington, Court of Federal Claims No: 13-0287V. 46. Jessica L. Stone, Baraboo, Wisconsin, Court of Federal Claims No: 13-0289V. 47. Holly Rhew, Wichita, Kansas, Court of Federal Claims No: 13-0293V. 48. Janet DeYear, Dallas, Texas, Court of Federal Claims No: 13-0299V. 49. Cynthia Adkins, Sarasota, Florida, Court of Federal Claims No: 13-0295V. 50. Saurabh V. and Archana Amin on behalf of Sheaa Amin, Linwood, New Jersey, Court of Federal Claims No: 13-0300V. 51. Juliet and Mohamed Edoo on behalf of Justin Edoo, Miami, Florida, Court of Federal Claims No: 13-0302V. 52. James Boyer, Boston, Massachusetts, Court of Federal Claims No: 13-0303V. *these are from March 13, 2013 – April 30, 2013. 48 days. what is the true number that these 52 petitions represent? how many don’t file claims? think about it..its scary. I wish we could see more about these petitions..more about the injury caused.It is impossible for a parent to make a solid risk/benefit analysis when it comes to vaccinations.. I don’t care what anyone may say.. vaccine injury is downplayed and pushed aside, disease rates and risks are over exaggerated and blasted throughout the media via mass scare campaigns (remember those 8 measly cases of the measles in Wales during the month of march 2013?) ..and natural and safe preventative measures and treatments are suppressed. How are we supposed to make an informed medical decision when it comes to our children being injected with almost 50 doses of 16 vaccines before the age of 6? https://www.federalregister.gov/articles/2013/05/24/2013-12347/national-vaccine-injury-compensation-program-list-of-petitions-received?utm_content=next&utm_medium=PrevNext&utm_source=Article “In 1990, infants received a total of 15 vaccine doses prior to their first year of life: 3 DPT injections (9 vaccine doses), 3 polio, and 3 Hib vaccines—5 vaccine doses at 2, 4, and 6 months of age. By 2007, the CDC recommended 26 vaccine doses for infants: 3 DTaP, 3 polio, 3 Hib, 3 hepatitis B, 3 pneumococcal, 3 rotavirus, and 2 influenza vaccines. While each childhood vaccine has individually undergone clinical trials to assess safety, studies have not been conducted to determine the safety (or efficacy) of combining vaccines during a single physician visit as recommended by CDC guidelines. For example, 2-, 4-, and 6-month-old infants are expected to receive vaccines for polio, hepatitis B, diphtheria, tetanus, pertussis, rotavirus, Haemophilus influenzae type B, and pneumococcal, all during a single well-baby visit—even though this combination of 8 vaccine doses was never tested in clinical trials. An article written by Guess, representing a vaccine manufacturer, claimed that it is “impractical to conduct preapproval studies of all combinations [of vaccines] in clinical practice.”1 However, a recent study by Miller and Goldman found that among the developed nations, infant mortality increased with an increase in the number of vaccine doses.2 Similar associations have also been found with respect to other serious adverse outcomes. Delong reported that the higher the proportion of children receiving recommended vaccinations, the higher the prevalence of autism or speech and language impairment.3 A CDC report on mixed exposures to chemical substances and other stressors, including prescribed pharmaceuticals, found that they may produce “increased or unexpected deleterious health effects.” In addition, “exposures to mixed stressors can produce health consequences that are additive, synergistic, antagonistic, or can potentiate the response expected from individual component exposures.

“The Health Resources and Services Administration (HRSA) is publishing this notice of petitions received under the National Vaccine Injury Compensation Program.. A pet…ition may be filed with respect to injuries, disabilities, illnesses, conditions, and deaths resulting from vaccines described in the Vaccine Injury Table… Set forth below is a list of petitions received by HRSA on * March 13, 2013, through April 30, 2013.*” [take note of #7 and #17..] 1. Tory J. and Sarah E. Moody on behalf of Victorya E. Moody, Bedford, Indiana, Court of Federal Claims No: 13-0190V. 2. Pamela Jean Peguess, Memphis, Tennessee, Court of Federal Claims No: 13-0191V. 3. Eileen Goeschel, Sarasota, Florida, Court of Federal Claims No: 13-0199V. 4. Kearsten Demczuk, Park Ridge, Illinois, Court of Federal Claims No: 13-0205V. 5. Howard Reddy and Hanan Tarabay on behalf of Andrew Howard Reddy, Pensacola, Florida, Court of Federal Claims No: 13-0208V. 6. Mona Marie Troup, Everett, Washington, Court of Federal Claims No: 13-0209V. 7. Angel Blackstone on behalf of S.B., Deceased, Trenton, New Jersey, Court of Federal Claims No: 13-0213V. 8. Isidra Durwin, Sarasota, Florida, Court of Federal Claims No: 13-0214V. 9. Nancy and Sandro Giannetta on behalf of A.M.G., Sarasota, Florida, Court of Federal Claims No: 13-0215V. 10. Kimberly Pedersen, West Allis, Wisconsin, Court of Federal Claims No: 13-0216V. 11. Charles and Jeannie Maikish on behalf of S.M., Nyack, New York,Court of Federal Claims No: 13-0217V. 12. Ina Scanlon, Muncie, Indiana, Court of Federal Claims No: 13-0219V. 13. David Stachlewitz on behalf of H.G.S., Glendale, Arizona, Court of Federal Claims No: 13-0220V. 14. Mary E. Thompson, Brookport, Illinois, Court of Federal Claims No: 13-0222V. 15. Matthew Gorski, Wynnewood, Pennsylvania, Court of Federal Claims No: 13-0224V. 16. Woodrow Coffey, Jr., Irvine, California, Court of Federal Claims No: 13-0225V. 17. Stephen Warren on behalf of Taylor Warren, Deceased, New York, New York, Court of Federal Claims No: 13-0226V. 18. Robert Wiggins, Nashville, North Carolina, Court of Federal Claims No: 13-0228V. 19. Peggy Kalmeyer, Depew, New York, Court of Federal Claims No: 13-0230V. 20. Rosemary and Wayne Trezza on behalf of P.T., West Orange, New Jersey, Court of Federal Claims No: 13-0231V. 21. Jane Tomassetti, Woodbury, Minnesota, Court of Federal Claims No: 13-0234V. 22. Everett Johnson, Sr., Ashland, Kentucky, Court of Federal Claims No: 13-0235V. 23. Edwin W. Fockler, Sarasota, Florida, Court of Federal Claims No: 13-0237V. 24. James Cox, Las Cruces, New Mexico, Court of Federal Claims No: 13-0238V. 25. Chanel and Paul A. Monroe on behalf of Angelina Monroe, Las Vegas, Nevada, Court of Federal Claims No: 13-0239V. 26. Noteel Koss, Houston, Texas, Court of Federal Claims No: 13-0240V. 27. Tamika M. Kratzer on behalf of Ian M. Kratzer, Sacramento, California, Court of Federal Claims No: 13-0243V. 28. Rosalie Peck, Boston, Massachusetts, Court of Federal Claims No: 13-0249V. 29. Shannon Keller, Sacramento, California, Court of Federal Claims No: 13-0250V. 30. Edwina Bradshaw, North Myrtle Beach, North Carolina, Court of Federal Claims No: 13-0252V. 31. William and Brenda Lehann Rodriguez on behalf of C.R., Clayton, Georgia, Court of Federal Claims No: 13-0253V. 32. Corrine K. Ibana, Kamuela, Hawaii, Court of Federal Claims No: 13-0257V. 33. Lorel Cubano, San Juan, Puerto Rico, Court of Federal Claims No: 13-0259V. 34. Brittany and Davey Lambert on behalf of Noah Lambert, Memphis, Tennessee, Court of Federal Claims No: 13-0265V. 35. Scott and Caroline VanScoy on behalf of Alyssa VanScoy, Simi Valley, California, Court of Federal Claims No: 13-0266V. 36. Jane Sprecher, Reading, Pennsylvania, Court of Federal Claims No: 13-0271V. 37. Georgia Murdock, Silver Spring, Maryland, Court of Federal Claims No: 13-0273V. 38. Willie Andre Simmons, Augusta, Georgia, Court of Federal Claims No: 13-0274V. 39. Jung Park, M.D., New York, New York, Court of Federal Claims No: 13-0275V. 40.

“Thus the MMR antibody in autistic sera detected measles HA protein, which is unique to the measles subunit of the vaccine. Furthermore, over 90% of MMR antibody-positive autistic sera were also positive for MBP autoantibodies, suggesting a strong association between MMR and CNS autoimmunity in autism. Stemming from this evidence, we suggest that an inappropriate antibody response to MMR, specifically the measles component thereof, might be related to pathogenesis of autism.” http://www.ncbi.nlm.nih.gov/pubmed/12145534  Influenza: marketing vaccine by marketing disease Closer examination of influenza vaccine policies shows that although proponents employ the rhetoric of science, the studies underlying the policy are often of low quality, and do not substantiate officials’ claims. The vaccine might be less beneficial and less safe than has been claimed, and the threat of influenza appears overstated. http://www.bmj.com/content/346/bmj.f3037 An unmasking phenomenon in an observational post-licensure safety study of adolescent girls and young women. Our recent experience in a post-licensure safety study of autoimmune conditions following the quadrivalent human papillomavirus vaccine in 189,629 girls and young women ages 9-26 years led us to question the adequacy of the exclusion of Day 0 events to prevent the erroneous association of prevalent conditions with vaccination. Of the 18 confirmed cases of Graves’ disease diagnosed in days 1-60 following vaccination, only 6 cases appeared to be truly new onset. Among the remaining 12 cases, 2 cases had abnormal thyroid stimulating hormone or thyroxine labs drawn prior to or on Day 0 but had no documented pre-existing symptoms. The other 10 cases had mention of symptoms of hyperthyroidism referencing a period prior to first HPV-4 dose. This ‘unmasking’ phenomenon, due to health care visits that include vaccination and new workups of preexisting symptoms, may not be adequately controlled through the exclusion of Day 0 events. http://www.ncbi.nlm.nih.gov/m/pubmed/22580356/   How aluminum, an intracellular ROS generator promotes hepatic and neurological diseases: the metabolic tale Metal pollutants are a global health risk due to their ability to contribute to a variety of diseases. Aluminum (Al), a ubiquitous environmental contaminant is implicated in anemia, osteomalacia, hepatic disorder, and neurological disorder. In this review, we outline how this intracellular generator of reactive oxygen species (ROS) triggers a metabolic shift towards lipogenesis in astrocytes and hepatocytes. This Al-evoked phenomenon is coupled to diminished mitochondrial activity, anerobiosis, and the channeling of α-ketoacids towards anti-oxidant defense. The resulting metabolic reconfiguration leads to fat accumulation and a reduction in ATP synthesis, characteristics that are common to numerous medical disorders. Hence, the ability of Al toxicity to create an oxidative environment promotes dysfunctional metabolic processes in astrocytes and hepatocytes. These molecular events triggered by Al-induced ROS production are the potential mediators of brain and liver disorders.” Advertisement The Role of Spiritual Enlightenment a... An Analogy with Butterfly Metamorphosis Today’s discourse touches upon the in... http://link.springer.com/article/10.1007%2Fs10565-013-9239-0 Waning of Maternal Antibodies Against Measles, Mumps, Rubella, and Varicella in Communities With Contrasting Vaccination Coverage Conclusions: Children of mothers vaccinated against measles and, possibly, rubella have lower concentrations of maternal antibodies and lose protection by maternal antibodies at an earlier age than children of mothers in communities that oppose vaccination. This increases the risk of disease transmission in highly vaccinated populations. http://jid.oxfordjournals.org/content/early/2013/04/29/infdis.jit143.full “vaccine injury is so rare..don’t worry about it!” who has heard this?

The Refurbished Rogue's Blog the random scribbles and unrestrained convictions of a wayward fool liberated by grace Main menu Skip to content Finding God vaccination my thoughts on true christianity my list of peer reviewed vaccine research what’s wrong with this world! forgiveness thinking free About redemption God is Love The bible is smart my testimony Fluoride is bad for you homeschool stuff SEARCH GO May 3, 2013 my list of peer reviewed vaccine research • 57 Comments This list is just a thrown together list and is pretty helter skelter..but, there are a lot of links to lead you down the research path if you are searching. There are are so many, many, many more out there that haven’t made it to this list. They sit and wait for me to find them..i better get to looking.. May our truth digging be successful! Hypothesis: conjugate vaccines may predispose children to autism spectrum disorders. the potential effects of conjugate vaccines on neural development merit close examination. Conjugate vaccines fundamentally change the manner in which the immune systems of infants and young children function by deviating their immune responses to the targeted carbohydrate antigens from a state of hypo-responsiveness to a robust B2 B cell mediated response. This period of hypo-responsiveness to carbohydrate antigens coincides with the intense myelination process in infants and young children, and conjugate vaccines may have disrupted evolutionary forces that favored early brain development over the need to protect infants and young children from capsular bacteria. http://www.ncbi.nlm.nih.gov/pubmed/21993250 Serological association of measles virus and human herpesvirus-6 with brain autoantibodies in autism. Considering an autoimmunity and autism connection, brain autoantibodies to myelin basic protein (anti-MBP) and neuron-axon filament protein (anti-NAFP) have been found in autistic children. In this current study, we examined associations between virus serology and autoantibody by simultaneous analysis of measles virus antibody (measles-IgG), human herpesvirus-6 antibody (HHV-6-IgG), anti-MBP, and anti-NAFP. We found that measles-IgG and HHV-6-IgG titers were moderately higher in autistic children but they did not significantly differ from normal controls. Moreover, we found that a vast majority of virus serology-positive autistic sera was also positive for brain autoantibody: (i) 90% of measles-IgG-positive autistic sera was also positive for anti-MBP; (ii) 73% of measles-IgG-positive autistic sera was also positive for anti-NAFP; (iii) 84% of HHV-6-IgG-positive autistic sera was also positive for anti-MBP; and (iv) 72% of HHV-6-IgG-positive autistic sera was also positive for anti-NAFP. This study is the first to report an association between virus serology and brain autoantibody in autism; it supports the hypothesis that a virus-induced autoimmune response may play a causal role in autism. http://www.ncbi.nlm.nih.gov/pubmed/9756729 Effectiveness of pertussis vaccines for adolescents and adults: case-control study The adjusted estimate of effectiveness of Tdap vaccination against pertussis was 53.0. http://www.bmj.com/content/347/bmj.f4249 Neurologic Adverse Events Following Vaccination (Progress in Health Sciences Vol. 2(1) 2012•pp 129-141.) “Conclusions: Despite the assurances of the necessity and safety of vaccinations, there are more and more questions and doubts, which both physicians and parents are waiting to be clarified… It seems that it would be worthwhile to apply the precautionary principle – the ethical principle (from 1988) according to which if there is a probable, although poorly known, risk of adverse effects of new technology, it is better not to implement it rather than risk uncertain but potentially very harmful consequences.” http://progress.umb.edu.pl/sites/progress.umb.edu.pl/files/129-141.pdf Abnormal measles-mumps-rubella antibodies and CNS autoimmunity in children with autism.

what’s wrong with this world! THINGS THAT MATTER TO ME Finding God Fluoride is bad for you God is Love homeschool stuff my take on proverbs my testimony my thoughts on true christianity on when God grew skin redemption spiritual warfare The bible is smart the praying parent thinking free To Train Up A Child Uncategorized vaccination what's wrong with this world! FOLLOW BLOG VIA EMAIL Enter your email address to follow this blog and receive notifications of new posts by email. Email Address: Follow REFURBISHED ROGUE – FACEBOOK STYLE I WILL SPEAK FOR THOSE WHO CANNOT. ABOLISH HUMAN ABORTION. May 2013 M T W T F S S   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31   « Apr   Jun » BLOGROLL Discuss Get Inspired Get Polling Get Support Learn WordPress.com Theme Showcase WordPress Planet WordPress.com News Advertisements <img src="https://sb.scorecardresearch.com/p?c1=8&c2=6820648&c3=1&c4=&c5=&c6=&cj=1&rn=1687185779190" /> REPORT THIS AD Top Posts & Pages good blogs Blogroll WordPress.com News Discuss Get Polling Learn WordPress.com WordPress Planet Get Support Theme Showcase Get Inspired Blog at WordPress.com. • Follow Privacy & Cookies: This site uses cookies. By continuing to use this website, you agree to their use. To find out more, including how to control cookies, see here: Cookie Policy <img src="https://pixel.wp.com/b.gif?v=noscript" style="height:1px;width:1px;overflow:hidden;position:absolute;bottom:1px;" alt="" />

Results: It was found in all the cases reported here the response to antigenic stimulation damaged the Beta cells in the Pancreas causing Hypoinsulinaemia which inhibited the cellular uptake of Vitamin C resulting in liver dysfunction, failure of carboxylation of the Vitamin K dependent proteins resulting in haemorrhages and fractures associated with the “triad”. Conclusion: Fractures, retinal and subdural haemorrhages and encephalopathy in children – is an autoimmune response to antigenic stimulation in a genetically susceptible individual. Common antigens are the mandated vaccines, viral bacterial and parasitic infections. ” Interpretation “In all four cases shown here there is evidence that hyperglycaemia followed vaccination and hyperglycaemia implies hypoinsulinism, an autoimmune disorder resulting from the destruction of the Beta cells of the pancreas. Since insulin is required for the transfer of vitamin C into the cells the intracellular vitamin C is reduced[12]. The resulting “tissue scurvy” compromises the function of the Liver by inhibiting carboxylation of the clotting and bone forming factors and is manifested as the signs and symptoms of the “triad”. Both Dr Kalokerinos and Professor Clemetson recommended giving the infant Vitamin C before vaccination but it would seem more appropriate to do an intradermal skin test to test for sensitivity in every case. Both were firmly of the view that a metabolic abnormality of Vitamin C was the essential cause of the signs and symptoms of the alleged “Non-accidental injuries”. ” Michael D Innis. Autoimmunity and Non-Accidental Injury in Children. Clinical Medicine Research. Vol. 2, No. 3, 2013, pp. 40-44. doi: 10.11648/j.cmr.20130203.15 Click to access 10.11648.j.cmr.20130203.15.pdf Reply the referbished rogue August 28, 2014 at 9:43 pm Thank you 🙂 I will add this along with some others. Reply Megan @LivingWhole.org September 6, 2014 at 8:37 pm Wow! You really did your research! I am very impressed and am glad I came across your blog. Keep it up. 🙂 Reply the referbished rogue September 7, 2014 at 11:01 am If this is Megan from the living whole that recently published the article about God not liking vaccines.. wow!! I am honored!! Your website is awesome. Reply Marcella Piper-Terry February 2, 2015 at 11:22 am Thank-you so much for this amazing resource! I would love to share it as a guest blog on VaxTruth.org. Reply the referbished rogue February 2, 2015 at 5:27 pm Oh wow! Thank you thank you! Of course you may! I am tickled right now 🙂 and honored for you to have read my blog!!! I love TTMR! Reply the referbished rogue February 2, 2015 at 5:31 pm I love vax truth as well.. I was so excited I don’t know what I wrote! God bless!! punyahannawilbur February 3, 2015 at 4:55 am Reblogged this on Hanna Wilbur's. Reply Lou July 22, 2015 at 11:08 pm Praise God for this site! Reply Leave a Reply Your email address will not be published. Required fields are marked * Comment * Name * Email * Website Notify me of new comments via email. Notify me of new posts via email. RECENT POSTS Abortion is forever Why we should welcome homosexuals into our churches – the thoughts of an evangelical, pentecostal Christian (no title) On Peace and the Little Girl Who Altered My Heart “Vaccines Saved Us” – Intellectual Dishonesty At Its Most Naked MOST VIEWED RECENT POSTS my list of peer reviewed vaccine research On Peace and the Little Girl Who Altered My Heart Biblical reasons to oppose vaccination Read the back of your toothpaste - fluoride IS poison. if there's doubt - GET IT OUT! WHAT WOULD YOU LIKE TO READ ABOUT? what would you like to read about? Select Category Finding God Fluoride is bad for you God is Love homeschool stuff my take on proverbs my testimony my thoughts on true christianity on when God grew skin redemption spiritual warfare The bible is smart the praying parent thinking free To Train Up A Child Uncategorized vaccination

This is a hard science, called Epigenetics. Reply Judy March 12, 2014 at 6:55 pm So many Newspapers are pushing provax messages – these journalists have not done any research. It is important to add to the comments whenever you can – not only do you educate the journalists but you may help inform the public and give another view. Love your Blog – great information, thank you so much. Reply the referbished rogue March 15, 2014 at 1:56 am Your welcome so much, Judy 🙂 it makes me happy when I get a notification that this post has been viewed by someone referred to it from a comment on a pro vax, propaganda article. God bless 🙂 Reply Chris March 14, 2014 at 2:28 am Keep up the good work!! The world is waking up. .. Reply Gabriel March 19, 2014 at 8:15 pm Thanks for doing all this work. I do have one question. How do you know that the articles are “peer reviewed”? Thanks! Reply the referbished rogue March 30, 2014 at 6:31 pm Your welcome Gabriel.. And thank you. All the links are to articles that have been published in journals that have a panel of medical / science professionals which must approve the data and the integrity of the article before it is allowed to be published. Reply David Fenton December 20, 2015 at 6:13 pm Hi, I’m developing a web site called real-morality and would like to use you list of peer reviewed articles as is, with a credit to you and link. In time I might organise them into some logical groups. My website is still in parking mode. Thanks and appreciation the referbished rogue January 16, 2016 at 9:20 pm Sure, that sounds fine. Thank you for wanting to include it. God bless, briana David September 2, 2015 at 11:00 am Most of these are from NIH. I’ve found these myself as well. You can’t get more peer-reviewed than a government health and technology agency. Reply Chris Robison March 30, 2014 at 6:04 pm bless you for doing this!! but I thought all anti-vaxxers are “anti-science”.. that’s what the science magazines all tell us.. 🙂 Reply Tina "I" April 2, 2014 at 6:48 am Wow! This is wonderful! Thanks so much for the time you have put into this, and especially for “sharing”. Everyone needs to keep getting the word out, so those that blindly follow, might eventually get their wake-up call… Hopefully, before it’s too late. Thank you! Thank you! Thank you! So nice to have it all in one place, as a reference. Reply the referbished rogue April 2, 2014 at 10:47 am Your welcome.. And thank you for commenting (every girl likes to feel special sometimes..ha) God bless! Reply Merideth April 19, 2014 at 8:34 pm Can you add a Pinterest link, so I can pin it, and keep it forever! Thanks Reply the referbished rogue April 21, 2014 at 6:06 pm Yes :)… Once I figure it out and am at my desktop..I will add it. Reply Shane Thepeopleschemist Ellison April 28, 2014 at 6:49 pm Good parent! Reply Lee June 14, 2014 at 5:21 pm Awesome job!!!!! Thanks Reply Kim July 14, 2014 at 8:37 pm Thank you SO VERY MUCH for doing this! I have been helping members of my family research this issue (some of them for the very first time); this will help tremendously. Reply Melinda Blondeaux July 27, 2014 at 12:09 pm You will probably want to add this one too: Abstract: “Background: The Shaken Baby Syndrome conceived by Guthkeltch to explain bruises, fractures, retinal and cerebral haemorrhage and encephalopathy in children, called the “triad”, can be explained by an autoimmune reaction to antigens in a genetically susceptible child. Method: Children diagnosed as suffering from Non-accidental injuries were investigated for evidence of immune response reactions following mandated vaccination and childhood illnesses.

the referbished rogue November 17, 2013 at 10:36 pm I just thought about this post..i wrote this over a year ago but this touches on our discussion and this is from my heart. https://therefurbishedrogue.wordpress.com/2012/07/03/on-the-child-i-lost-the-child-who-waits-for-me/ Pingback: Vaccine Research » My Autistic Muslim Child Pingback: Am I a murderer? | Soul Reflection shanklandfamily September 13, 2013 at 6:11 pm What an amazing list! Thank you SO MUCH for putting this together!! I have been looking for more factual information like this and your list is just what I need to get started in my reading. Your hard work is much appreciated. Reply the referbished rogue September 15, 2013 at 4:27 am So very glad to hear it. God bless! Reply Kathleen E W Bailey September 15, 2013 at 4:14 pm Reblogged this on Soul Kitty and commented: Wow, a wealth of info! Reply Sheri Nakken, former RN, MA, Hahnemannian Homeopath November 17, 2013 at 7:02 pm What an incredible list you have compiled! Wonderful and thank you. Will have to read further and see who you are! Reply the referbished rogue November 17, 2013 at 9:03 pm thank you and your welcome! ohh Lord..im afraid of what you may find. Laugh, laugh. God bless you! Reply puameliaclinic November 17, 2013 at 10:43 pm Reblogged this on The Pua Melia Clinic and commented: A page on getting some papers on Jab research Reply notidlechatter November 18, 2013 at 1:45 pm I love all the titles to your blogs. It seems as if we have been on a similar journey. I also bask in God’s grace and seek to share the truths He teaches me with others. I have a particular interest in health, wellness and avoiding vaccines. I am learning about the technology I need to get the message out more effectively. I’ve started a blog at http://www.journeyboost.com I appreciate all the work you have put in and I wish all my friends and acquaintances who want to convince me that the science supports vaccines would read every article! Thank you. Reply the referbished rogue November 18, 2013 at 4:58 pm Thank you for the encouragement! Seriously..that meant a lot to me. I can’t wait to.check out your blog 🙂 In Christ’s love and maranatha – briana Reply Lou January 7, 2014 at 6:45 am Wonderful – many thanks. In my own years of research, it always bugged me why some children / people were effected and others not (I get this question sometimes). There are a few that I recall which explains why: 1. manufacture conditions can vary and ingredients/contamination occurs in “batches”. 2. temperature control 3. varying levels of toxic additives (e.g. mercury – can be more damaging if the vial is not shaken before injection) 4. the state of the immune system 5. autism is higher in boys because of the way mercury reacts with male hormones. Just to name a few….Certain groups are used more for “guinea pig” testing than other groups. Reply the referbished rogue January 7, 2014 at 9:59 am Very good reasoning! I agree with you. It’s a shame that an industry that affects ( I really hope i used the right one there. . I always question myself ha) isn’t more aware and looking to fix these issues for the sake of the millions of children who, by blind faith, are subjected to these things. God bless you. – briana Reply David September 2, 2015 at 10:58 am It’s about genetics. Some people have gene combinations that don’t allow them to methylate the toxins in Vaccines (along with other genes that contribute to adverse reactions in other ways). Meaning, their body doesn’t detect the toxins and therefore doesn’t get rid of them, so you have Aluminum, Mercury and other carcinogenics circulating in the system or burying into cells. There are therapies such as Chelation which flush these toxins, so there is hope. The problem is that NO ONE does genetic testing prior to Vaccination to determine if this is a problem. This is why some people have adverse reactions to Vaccines and some do not.

CARMEN WHITE May 4, 2013 at 10:35 pm This is so AWESOME!!!! Thank you for taking the time to put this together. Hopefully with more people like you, we can continue to educate more parents about the harmful effects of vaccines. Reply sandy fleming May 5, 2013 at 1:53 am I am really curious, how did you find these? I thought I was pretty good at googling, but never came across so much hard science when I did my research, instead I’d come across something on “Natural News” but never able to find these peer reviewed studies. If you don’t mind sharing, can you tell me how you found most of these? Reply Pingback: my response to a friend who fears vaccination and is unsure what to do. | The Refurbished Rogue's Blog myautisticmuslimchild June 1, 2013 at 1:24 am Thank you for this post. i will be posting this link on my blog. I researched a lot, bc my son’s problem started after his 13 months vaccine (rather 12 but i was late for 1 month). i always swear by that his autism has something to do with his vaccination since he got so sick after 4 combination shots. We are still struggling, but if I can help other families to make a better decision about vaccination ut will worth all the fight. Reply the referbished rogue June 1, 2013 at 1:57 am thank you for the kind words. I don’t know how God decides which children will become autistic..but I do know that he chooses strong families who are not broken by this condition and he chooses parents like yourself who search to help others even through their own challenges. Thank you for allowing others to enter into your world and learn from your experiences. Keep fighting the good fight -briana Reply Sheri Nakken, former RN, MA, Hahnemannian Homeopath November 17, 2013 at 7:03 pm I really don’t think God decides this…………….my God doesn’t cause injury or harm or pain. It is humans who do this. the referbished rogue November 17, 2013 at 9:09 pm You are right..evil does not come from God but from sinful man. I do, however, believe that God allows bad things to happen at times for a higher purpose. For a purpose that only He knows. He allows bad things to happen only when the outcome from them will do good things. example: a Christian lady has cancer but while she is in the hospital, she witnesses to her roommate and her roommate becomes a follower of Jesus Christ. There could be two endings to this story..both good, one – the lady could receive healing and go on to live a long life. or two – the Lord could take her to spend an eternity with Him. Sheri Nakken, former RN, MA, Hahnemannian Homeopath November 17, 2013 at 9:13 pm those outcomes could happen, but a perfect loving God could NOT cause these things, or even allow these things (if allowed them, is not the perfect God). I have a different view on this. If God allows or causes, then God is not a perfect loving being. Yes, those outcomse could happen, but not because God uses us in this way. the referbished rogue November 17, 2013 at 10:06 pm The world that God intented for us to live was perfect..no pain..no sadness. But because God gave us freewill and is not a dictator..man chose to go against God and sin entered this world. From that point on..man has had to toil to eat..women scream out in pain during childbirth. But out of these hardships do you not still see love? Food to fill our bellies and children to love. The ultimate reason that I know that God is love through all the darkness..is that He sent his son Jesus Christ to die for our sins so that we may have life. Nothing that happens to us on this earth matters when you realize that heaven is ours because of what Jesus did on behalf of His Father. Just one example I would like for you look into if you like, is the book of Job. Regardless that we may see some things differently..let us keep our eyes on what really matters. Let us keep our eyes on Jesus. http://www.gotquestions.org/God-allow-Satan-attack.html