Group( D )

All plasma iron is bound to transferrin and is measurable through plasma iron test

Plasma Iron Only ..... of total iron (50-70 mmol or 3-4 mg) circulates in plasma.

Haemoglobin Holds most circulating iron........in red blood cells for oxygen transport.

....... Store iron in the liver, spleen, and bone marron

.........Transports iron in plasma.

Iron is found in various compartments, with constant exchange between stores and plasma .

The body contains about ...... of iron.

Each haemoglobin molecule consists of ....... haem groups (each containing one iron atom)

Globin proteins are synthesized in ..... and consist of alpha and beta chains

the final step, ferrous iron (Fe2+) is inserted into protoporphyrin IX by the enzyme.......forming heam

Coproporphyrinogen III re-enters the mitochondria and is converted into ......

ALA moves to the cytoplasm, where it undergoes several transformations, eventually forming.......

........ being lipid-soluble, is transported to the liver, where it undergoes further modification for excretion via bile.

Biliverdin :

Iron is released and recycled for future haemoglobin production, conserving the body’s iron stores.

The haem ring structure is opened by the enzyme haem oxidase to form .....

.......The protein component, which is broken down into amino acids and returned to the general protein pool

• The ..... is a primary non-bone-marrow site for haem production.

heam is use to make......a protein that stores oxygen in muscles,