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كل شي يخص طب الاسنان القناة بيها مصادر و شرحيات و كويزات صاحب القناة :- مصطفى إبراهيم اسماعيل @h4mr2 رابط متجر المستلزمات :- https://t.me/dentalspacesuppiles تاريخ انشاء القناة :- 2022/3/20
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مهمات ملزمة. ١١ و ١٢ بايو كمستري
و ركزوا حيل ع
factors that effect enzymes activity
2 152
Lecture 13 , 14
شرح بسيط ع كل الانزيمات بهاي المحاضرة
🔴 Pancreatic enzyme
1) Alph - amylase
Molecular weight :-
(54 - 62 kDa)
Normal values :-
28-100 U/L = 0.48 - 1.7 i kat/ L
▪️they are the only plasma enzyme physiologically found in urine
2) lipase
Molecular weight :-
48 kDa
Normal values :-
40-200 U/L
▪️ serum amylase increases in mumps , pancreatic disease or other diseases while lipase increase only in pancreatitis
3) trypsin
Normal values :-
25 (+ or -) 5.3 u g/L
▪️Increased in pancreatic 🦠
🔴 liver enzymes
🔹 markers of hepatocellular damage
1) amino-transferases / transaminases
▪️elevated plasma ALT are considered to be relatively specific liver disease 🦠
▪️elevated plasma AST in myocardial fraction , muscle necrosis and renal disease 🦠
▪️ALT level increased more than AST
Normal range
▫️ AST
. male = < 35 U/L = 0.60 mkat/L
.female = <31 U/L = 0.53 mkat/L
▫️ ALT
. Male = <45 U/L = 0.77 mkat/L
. Femal = <34 U/L = 0.58 mkat/L
🔹 marker of cholestasis
1) ALP
Half life = 10 days
▪️ALP are group of enzymes that hydrolyses organic phosphate at high PH
▪️the exact metabolic function of ALP is unknown but it is probably important for classification of bone 🦴
2) gamma- glumly- tranfersase
▪️ Plasma GGT activity is higher in men than in women
Normal values :-
.male = <55 U/L = 0.94 mkat/L
.female = 38 U/L = 0.68 mkat/L
🔴 other enzymes
1) chilineesterase
Normal values :-
4.9 - 11.9 U/mL
▪️ measurement of CHE is used as a indicator of a possible insecticide poisoning
🔴 muscle enzymes
1) creatine kinase (CK)
Normal values :-
.male = 46-171 U/L = 0.78 - 2.90 ukat/L
.female = 34-145 U/L = 0.58 - 2.47 ukat/L
2) lactate dehydrogenase
Molecular weight :- 134 kDa
Normal range :-
180-360 U/L = 3.1 -6.1 ukat/L
▪️ is composed of four petite chains of two types M and H each under separate a genatic control
LD-1 = H4
LD-2 = H3M
LD-3 = H2M2
LD-4 = HM3
LD-5 = M4
2 152
Repost from Dental Space
محاضرة 13-14 (clinical enzymology)
عندكم تروكات ضمنية بيها الي هي 👇🏼:-
1. Glutamate dehydrogenase
2. Acid phosphates
3. Glucose-6- phosphate dehydrogenase
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