GiT Updates and More

🌋Duodenal Ulcers: 🔹Defined as >5 mm disruption of the mucosal integrity leading to a submucosal exposure w/ perceptible depth at endoscopy 🔹Complications: bleeding, perforation, & stricture 🔹Usually located at duodenal bulb 🔹Bleeding ulcer: Forrest I, II, III

✅ Microscopic colitis (MC) is recommended to be ruled out in patients considered to have functional diarrhoea or irritable bowel syndrome with predominant diarrhoea, and all patients with MC should be screened for coeliac disease. ✳️ for details : https://doi.org/10.1177/2050640620945811

Lynch Syndrome (aka HNPCC) 👨🏻‍⚕️ discovered by Henry Lynch 1966 🧬 Gene defect > MLH1, MSH2, MSH6, PMS2 ✳️ 50%➡️👨‍👩‍👧‍👦 🔎 Found in 1/500; 3% of all CRCs ⚠️ Cancers👇 👨🏻‍🏫 Criteria for suspection : Amsterdam criteria (3-2-1 ✅): 3️⃣ 👨‍👩‍👧‍👦 Family with CRC (1x FDR) 2️⃣ generations 1️⃣ 👨‍👩‍👧‍👦 Dx <50yrs 🔦 Screening (50-80%➡️CRC) 🏁 Age 25 (35 if MSH6/PMS2) 🗓 2yrs

The 2020 ESC Guidelines and the addition of Landiolol in management of atrial fibrillation

⭕️ Therapy options for adrenal insufficiency and recommendations for the management of adrenal crisis 2021 ✅

Iron deficiency anemia in details ✅

Furosemide therapy

management of severe COPD Excerbations

acute kidney injury

2020 American College of Rheumatology Guideline for the Management of Gout

Hypertensive Encephalopathy, related to cerebral edema, is characterized by the insidious onset of headache, nausea, and vomiting, followed by nonlocalizing neurologic symptoms such as restlessness, confusion, and, if the hypertension is not treated, seizures and coma

Effect of Crohn’s disease ..

meta-analysis concluded that patients with IBD and taking PPI have increase in hospitalization rather than off ppi http://dx.doi.org/10.1136/gutjnl-2020-321609

✳️ American Gastroenterology Association Recommendations on management of acute diverticulitis