GiT Updates and More

💊Vonoprazan+high-dose amoxicillin is an effective & well-tolerated rescue therapy for persistent H.pylori In a multicenter RCT (n=688), dual therapy was non-inferior to quadruple therapy, with fewer side effects & good tolerance.

🔅Subclinical hypothyroidism can cause a significant increased risk of developing gallbladder stones and common bile duct lithiasis. 🔅Thus screening for SCH is highly recommended in any patient diagnosed with biliary lithiasis

Alteration in Liver Function and Manifestations of liver Failure

❇️ Main Causes of Acute Abdominal Pain by Age : 🔆 SCHOOL AGE (2-13 YEARS) ▪️Acute gastroenteritis or viral syndrome ▪️Urinary tract infection ▪️Appendicitis ▪️Trauma ▪️Constipation ▪️Pneumonia ▪️Sickling syndromes 🔆 ADOLESCENT

Symptoms the suggest causes of abdominal distention

❇️ In patients who have fever and chills it is important to consider the following associations: 🔹The presence of associated Heart murmur raises the possibility of SBE. 🔹The presence Jaundice raises the possibility of biliary infection e.g. ascending cholangitis and cholecystitis. 🔹The presence of associated Hepatomegaly raises the possibility of amoebic live abscess. 🔹The presence of associated Neurological signs raises the possibility of CNS infection.

Endoscopic band ligation for GAVE ( gastric antral vascular ectasia )

Good Algorithm for MASLD diagnosis

❇️ Post Polypectomy Bleeding:  ▫️Occur in 0.3 - 6% ▫️24% in large polyps 🔊 Risk factors :  👉 Polyps > 17 mm 👉 Right colon 👉 Stalks > 5mm 👉 Sessile polyps 👉 Maligant polyps 👉 Hypertension

Recommended elements to be included in an ileocolonoscopy report in patients with inflammatory bowel disease

Biopsy recommendations in the monitoring of IBD disease activity.

🔥Slim therapeutic gastroscope with large working channel - a game changer in upper GI endoscopy - 7.9 mm outer diameter - 3.2 mm working channel (allows for instrument/utensil maneuvering while suctioning water or air )

✳️ Antiemetics: • 5-HT3 antagonists – Ondansetron (post-chemotherapy-post operative ) • D2 antagonists – Metoclopramide, Domperidone (gastroparesis, migraine) • H1 blockers – Diphenhydramine, Meclizine (motion sickness, vertigo) • Neurokinin-1 (NK1)antagonists – Aprepitant (chemo-induced) • Steroids – Dexamethasone-adjunct in CINV (chemotherapy induced nausea and vomiting ) • Others – Benzodiazepines (anticipatory vomiting), Cannabinoids

Acute Pancreatitis