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شرح مادة الصيدلة السريرية clinical pharmacology 🧑🏻⚕️ معرف التلي: mohammedsalim10 Instagram: _a1mh
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The woman at greatest risk for developing breast cancer is:
A. African American aged 53 years with no family history of breast cancer
B. Canadian Caucasian aged 53 years with grandmother having a history of breast cancer
C. Ashkenazi Jew aged 53 years who tested negative for BRCA 1 and 2 mutations
D. Hispanic aged 53 years with a history of atypical hyperplasia and a sister with breast cancer
E. Asian aged 53 years who had taken oral contraceptives between 20 and 30 years of age
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Biologic or Targeted Therapy is one of approach for treatment of breast cancer. Which one of the following regimens is considered first line treatment for HER2 positive breast cancer?
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the common side effect of trastuzumab containing regimens is
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Which of the following independent factors influence the risk for breast cancer recurrence and subsequent metastatic disease
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Explain the concept of "dose intensity" in the context of chemotherapy regimens.
a- Refers to the specific dosage of a single drug used in treatment
b- Represents the total amount of a drug administered over the entire treatment course
c- Describes the concentration of the drug in the bloodstream at peak levels
d- Indicates the intensity of side effects experienced by the patient
e- indicate the amount of drug delivered per unit of time, impacting treatment efficacy
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Therapeutic outcomes of early breast cancer differ from those of advanced breast cancer based on treatment goals. During process of evaluating therapeutic outcomes; the goal of treating early breast cancer is
a- Cure
b- Improving quality of life
c- Palliation
d- Preventing deterioration
e- None of the above
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The following drug is used as a second-ling treatment in hormone receptor-positive metastatic breast cancer, postmenopausal women with disease progression following
antiestrogen therapy
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Sara is a 55 post-menopausal woman having a risk of developing breast cancer. The preferred medication for preventing breast cancer in Sara is
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Regarding stage IV breast cancer. All of the following are true EXCEPT:
a- The tumor is larger than that of the other stages
b- It can NOT be cured
c- It can be metastasized to the lungs
d- It has a positive lymph node involvement
e- Anastrozole is highly recommended to improve the quality of life.
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Which of the following modalities has negligible role in the management of metastatic breast cancer
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J.A. is 48 years old woman with breast cancer. Which factor for breast cancer? of the followings is a risk
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Which genetic mutations significantly increase the lifetime risk of breast cancer?
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A 66 years old woman is suffering from low mineral bone density and strong family history of breast cancer. What would be the best protective agent?
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Regarding the chemotherapy of breast cancer. The adjuvant chemotherapy regimens include all EXCEPT:
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37-year-old woman has a large mass on her left breast confirmed a diagnosis of inflammatory breast cancer, with ER negative, PR weakly positive and HER2 negative, no metastasis. The best neoadjuvant therapy for breast conserving surgery is
