اختبـارات الصيدلـة 💊.

A lower KD indicates a ______ binding affinity between the drug and plasma proteins

Drugs highly bound to proteins have delayed elimination, such as ______.

Increased free drug levels in plasma result in ______ therapeutic effects.

Highly bound drugs, such as ______ anticoagulants, can displace less tightly bound compounds.

Low plasma protein levels may occur in old age, malnutrition, or ______ diseases

Acidic drugs can be administered in the form of a ______ to enhance solubility

. Salts of weak acids and bases exhibit ______ solubility compared to their free forms

The diffusion coefficient (D) decreases as the ______ of the medium increases.

Surfactants in gastric juice increase drug ______ through micellization.

As particle size decreases, the rate of drug ______ generally increases

Gastric and intestinal motility ______ the thickness of the diffusion layer around the drug particles.

Smaller particle size results in a greater ______ area, which enhances the dissolution

A decrease in the thickness of the diffusion layer (h) leads to a ______ dissolution rate.

According to the pH-partition theory, the gastrointestinal epithelia acts as a ______ barrier for drugs absorbed by passive diffusion

The pH of the gastrointestinal tract influences the ______ and absorption of drugs

The absorption of weak electrolytes depends on the extent to which the drug exists in its ______ form at the site of absorption.

Lipid-soluble drugs pass across the barrier, while ionized drugs, which are ______ lipid-soluble, cannot